Lactose intolerance: A common childhood digestive problem

R. Alam,M. Rukunuzzaman,K. Nahid,Fahmida Begum

Published 2023 in Paediatric Nephrology Journal of Bangladesh

ABSTRACT

Intolerance to lactose-containing foods is not so uncommon. Clinical symptoms of lactose intolerance in children include abdominal pain, flatulence, and diarrhea after ingesting milk or milk-containing products. These symptoms have been attributed to lactose malabsorption, which results from low levels of small intestinal lactase. Reduced lactase level may be due to mucosal injury or, much more commonly, reduced genetic expression of the enzyme lactase-phlorizin hydrolase. However, lactose intolerance cannot be cured. Still, it can be adequately managed by using lactose-reduced milk and milk products and over-the-counter supplements of lactase, lactose-depleted products, and other essential milk nutrients such as calcium. This article will review the clinical manifestations, diagnosis, and management of lactose intolerance in children.

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