Molecular cloning of monkey liver cytochrome P-450 cDNAs: similarity of the primary sequences to human cytochromes P-450.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Biochimica et Biophysica Acta

• Publication date

  1992-12-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0167-4781(92)90113-EPMID 1282830
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular cloning of monkey P450 1A1 cDNA and expression in yeast.

  1992cited by this paper
• cDNA and deduced amino acid sequences of a dog liver cytochrome P-450 of the IIIA gene subfamily.

  1991cited by this paper
• The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

  1991cited by this paper
• Isolation of cDNAs coding for three different forms of liver microsomal cytochrome P-450 from polychlorinated biphenyl-treated beagle dogs.

  1990cited by this paper
• Comparative study of cytochrome P-450 in liver microsomes: A form of monkey cytochrome P-450, P-450-MK1, immunochemically cross-reactive with antibodies to rat P-450-male

  1989cited by this paper
• Purification of cytochrome P-450 from polychlorinated biphenyl-treated crab-eating monkeys: high homology to a form of human cytochrome P-450.

  1989cited by this paper
• Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450.

  1989cited by this paper
• Isolation of a new human fetal liver cytochrome P450 cDNA clone: evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers.

  1989cited by this paper
• Comparative study of cytochrome P-450 in liver microsomes. A form of monkey cytochrome P-450, P-450-MK1, immunochemically cross-reactive with antibodies to rat P-450-male.

  1989cited by this paper
• Effects of serum testosterone level with buserelin on the activities of drug and testosterone hydroxylase and on the content of a male-specific form of cytochrome P-450 in male rats.

  1989cited by this paper
• Complete Sequence of Cytochrome P450 3c cDNA and Presence of Two mRNA Species with 3′ Untranslated Regions of Different Lengths

  1988cited by this paper
• The non-human primate: a possible model for human genetically determined polymorphisms in oxidative drug metabolism.

  1988cited by this paper
• Characterization of multiple human cytochrome P-450 1 cDNAs. The chromosomal localization of the gene and evidence for alternate RNA splicing.

  1987cited by this paper
• Structural analysis and specific expression of microsomal cytochrome P-450(M-1) mRNA in male rat livers.

  1987cited by this paper
• Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase.

  1987cited by this paper
• cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC).

  1987cited by this paper
• Structural analysis of cloned cDNAs for polycyclic hydrocarbon-inducible forms of rabbit liver microsomal cytochrome P-450.

  1987cited by this paper
• Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

  1986cited by this paper
• Isolation and sequence determination of a cDNA clone related to human cytochrome P-450 nifedipine oxidase.

  1986cited by this paper
• Complete cDNA and protein sequence of a pregnenolone 16 alpha-carbonitrile-induced cytochrome P-450. A representative of a new gene family.

  1985cited by this paper
• Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1.

  1985cited by this paper
• Human dioxin-inducible cytochrome P1-450: complementary DNA and amino acid sequence.

  1985cited by this paper
• Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC.

  1984cited by this paper
• The murine Ah locus. Comparison of the complete cytochrome P1-450 and P3-450 cDNA nucleotide and amino acid sequences.

  1984cited by this paper
• Structural characteristics of cytochrome P-450. Possible location of the heme-binding cysteine in determined amino-acid sequences.

  1983cited by this paper
• Amino acid sequence of an analogous peptide from two forms of cytochrome P-450.

  1981cited by this paper
• Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.

  1980cited by this paper
• Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

  1979cited by this paper
• Screening lambdagt recombinant clones by hybridization to single plaques in situ.

  1977cited by this paper

• The impact of induced pluripotent stem cells in animal conservation

  2024cites this paper
• Long-acting reversible contraception with etonogestrel implants in female macaques (Macaca mulatta and Macaca fascicularis)

  2024cites this paper
• Preclinical Pharmacokinetics and in vitro Metabolism of FHND5071, a Novel Selective RET Kinase Inhibitor

  2023cites this paper
• Elimination of tucatinib, a small molecule kinase inhibitor of HER2, is primarily governed by CYP2C8 enantioselective oxidation of gem-dimethyl

  2022cites this paper
• CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate

  2021cites this paper
• Comparative Pharmacokinetics of Puerarin Alone and in Pueraria mirifica Extract in Female Cynomolgus Monkeys

  2020cites this paper
• Efficient Generation of Cynomolgus Monkey Induced Pluripotent Stem Cell-Derived Intestinal Organoids with Pharmacokinetic Functions

  2018cites this paper
• In Vitro-In Vivo Extrapolation of Intestinal Availability for Carboxylesterase Substrates Using Portal Vein-Cannulated Monkey.

  2017cites this paper
• Identification of cytochrome P450 isoforms involved in the metabolism of Syl930, a selective S1PR1 agonist acting as a potential therapeutic agent for autoimmune encephalitis.

  2017cites this paper
• A new approach to predicting human hepatic clearance of CYP3A4 substrates using monkey pharmacokinetic data

  2013influential citation
• Comparison of p450 enzymes between cynomolgus monkeys and humans: p450 identities, protein contents, kinetic parameters, and potential for inhibitory profiles.

  2013cites this paper
• Cytochrome P450 CYP3A in marsupials: cloning and identification of the first CYP3A subfamily member, isoform 3A70 from Eastern gray kangaroo (Macropus giganteus).

  2012cites this paper
• Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function

  2011influential citation
• Newly Identified CYP2C93 Is a Functional Enzyme in Rhesus Monkey, but Not in Cynomolgus Monkey

  2011cites this paper
• Genetic Variants of CYP 3 A 4 and CYP 3 A 5 in Cynomolgus and Rhesus Macaques

  2010cites this paper
• Functional characterization of CYP3As-humanized mice constructed by human artificial chromosome vector system and their application to drug-drug interaction study

  2010cites this paper
• Prediction of the Intestinal First-Pass Metabolism of CYP3A Substrates in Humans Using Cynomolgus Monkeys

  2010cites this paper
• Mechanism-Based Inactivation of Human CYP2E1 by Diethyldithocarbamate

  2010cites this paper
• Identification and characterization of CYP2C18 in the cynomolgus macaque (Macaca fascicularis).

  2010cites this paper
• Genetic Variants of CYP3A4 and CYP3A5 in Cynomolgus and Rhesus Macaques

  2010cites this paper
• Pregnancy Does Not Increase CYP3A or P-Glycoprotein Activity in the Non-Human Primate, Macaca nemestrina

  2009cites this paper
• A Null Allele Impairs Function of CYP2C76 Gene in Cynomolgus Monkeys: A Possible Genetic Tool for Generation of a Better Animal Model in Drug Metabolism

  2009cites this paper
• In Vivo Evaluation of Drug-Drug Interaction via Mechanism-Based Inhibition by Macrolide Antibiotics in Cynomolgus Monkeys

  2009cites this paper
• Effect of Oral Ketoconazole on Oral and Intravenous Pharmacokinetics of Simvastatin and Its Acid in Cynomolgus Monkeys

  2009cites this paper
• Cynomolgus monkey CYPs: a comparison with human CYPs

  2009influential citation
• Tissue-specific mRNA expression profiles of drug-metabolizing enzymes and transporters in the cynomolgus monkey.

  2009cites this paper
• Differentiation of monkey embryonic stem cells into hepatocytes and mRNA expression of cytochrome p450 enzymes responsible for drug metabolism: comparison of embryoid body formation conditions and matrices.

  2009cites this paper
• Cloning, expression, and characterization of CYP3A43 cDNA in cynomolgus macaque (Macaca fascicularis).

  2009cites this paper
• Biotransformation of Xenobiotics

  2009cites this paper
• Species differences in in vitro and in vivo small intestinal metabolism of CYP3A substrates.

  2008cites this paper
• Important amino acid residues that confer CYP2C19 selective activity to CYP2C9.

  2008cites this paper
• Effect of Oral Ketoconazole on Intestinal First-Pass Effect of Midazolam and Fexofenadine in Cynomolgus Monkeys

  2007cites this paper
• CYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans

  2007cites this paper
• Functional characterization of human and cynomolgus monkey cytochrome P450 2E1 enzymes.

  2007cites this paper
• Characterization of cynomolgus monkey cytochrome P450 (CYP) cDNAs: is CYP2C76 the only monkey-specific CYP gene responsible for species differences in drug metabolism?

  2007cites this paper
• Cynomolgus monkey cytochrome P450 2C43: cDNA cloning, heterologous expression, purification and characterization.

  2006cites this paper
• Species and strain differences in drug metabolism in liver and intestine

  2006cites this paper
• tolbutamide and testosterone.

  2006cites this paper
• Marked species differences in the bioavailability of midazolam in cynomolgus monkeys and humans

  2006cites this paper
• In Vivo and in Vitro Characterization of Chlorzoxazone Metabolism and Hepatic CYP2E1 Levels in African Green Monkeys: Induction by Chronic Nicotine Treatment

  2006cites this paper
• Species and strain differences in drug metabolism in liver and intestine

  2006cites this paper
• The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies.

  2006cites this paper
• CYP2C76, a Novel Cytochrome P450 in Cynomolgus Monkey, Is a Major CYP2C in Liver, Metabolizing Tolbutamide and Testosterone

  2006cites this paper
• Characterization of the Rhesus Monkey CYP3A64 Enzyme: Species Comparisons of CYP3A Substrate Specificity and Kinetics Using Baculovirus-Expressed Recombinant Enzymes

  2006influential citation
• Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction

  2006cites this paper
• Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism.

  2006cites this paper
• Species and strain differences in drug metabolism in liver and intestine

  2006cites this paper
• Molecular Cloning and Functional Analyses of OAT1 and OAT3 from Cynomolgus Monkey Kidney

  2005cites this paper
• [High throughput screening of pharmacokinetics and metabolism in drug discovery (II)--investigation on in vitro and in vivo correlation in drug metabolism screening].

  2005cites this paper
• Stimulatory Effects of Testosterone and Progesterone on the NADH-and NADPH-dependent Oxidation of 7β-Hydroxy-Δ8-tetrahydrocannabinol to 7-Oxo-Δ8-tetrahydrocannabinol in Monkey Liver Microsomes

  2005cites this paper
• Stimulatory effects of testosterone and progesterone on the NADH- and NADPH-dependent oxidation of 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol in monkey liver microsomes.

  2005cites this paper
• No regional differences of cytochrome P450 expression in the liver of Cynomolgus monkeys (Macaca fascicularis).

  2005cites this paper
• Human and animal hepatocytes in vitro with extrapolation in vivo.

  2004cites this paper
• Intravenous Pharmacokinetics and Metabolism of the Reactive Oxygen Scavenger α-Phenyl-N-Tert-Butyl Nitrone (PBN) in the Cynomolgus Monkey

  2004cites this paper
• Functional characterization of three human cytochrome P450 2E1 variants with amino acid substitutions

  2003cites this paper
• Monkey hepatic microsomal alcohol oxygenase: purification and characterization of a cytochrome P450 enzyme catalyzing the stereoselective oxidation of 7alpha- and 7beta-hydroxy-delta8-tetrahydrocannabinol to 7-oxo-delta8-tetrahydrocannabinol.

  2002cites this paper
• Cytochromes P450 and experimental models of drug metabolism

  2002cites this paper
• Species difference in nisoldipine oxidation activity in the small intestine.

  2002cites this paper
• Monkey Hepatic Microsomal Alcohol Oxygenase: Purification and Characterization of a Cytochrome P450 Enzyme Catalyzing the Stereoselective Oxidation of 7α- and 7β-Hydroxy-Δ8-tetrahydrocannabinol to 7-Oxo-Δ8-tetrahydrocannabinol

  2002cites this paper
• A novel cytochrome P450 enzyme responsible for the metabolism of ebastine in monkey small intestine.

  2001influential citation
• HISTORY OF DRUG METABOLISM RESEARCH IN JAPAN*

  2000cites this paper
• Cloning of canine cytochrome P450 2E1 cDNA: identification and characterization of two variant alleles.

  2000cites this paper
• Metabolic activity of fresh and cryopreserved cynomolgus monkey (Macaca fascicularis) hepatocytes

  2000cites this paper
• Molecular cloning, expression, and characterization of CYP2D17 from cynomolgus monkey liver.

  1999cites this paper
• A comparison of basal and induced hepatic microsomal cytochrome P450 monooxygenase activities in the cynomolgus monkey (Macaca fascicularis) and man.

  1999cites this paper
• Molecular cloning and functional analysis of cynomolgus monkey CYP1A2.

  1998cites this paper
• Function and its Application of Cytochrome P450: To Achieve Drug Metabolism Studies for Humans

  1998cites this paper
• Identification of CYP2E1 in marmoset monkey.

  1998cites this paper
• Nucleotide and amino acid sequences of the monkey P450 2B gene subfamily.

  1998cites this paper
• Chlorzoxazone 6-hydroxylase and p-nitrophenol hydroxylase as the most suitable activities for assaying cytochrome P450 2E1 in cynomolgus monkey liver.

  1998cites this paper
• Overview of experimental approaches for study of drug metabolism and drug-drug interactions.

  1997cites this paper
• Isolation of a bovine full length cytochrome P450 (CYP3A) cDNA sequence and its functional expression in V79 cells.

  1997cites this paper
• Marmoset liver cytochrome P450s: study for expression and molecular cloning of their cDNAs.

  1997cites this paper
• Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans

  1997cites this paper
• An Islet-Cell Protein Tyrosine Phosphatase Is a Likely Precursor to the 37-kDa Autoantigen in Type 1 Diabetes: Human and Macaque Sequences, Tissue Distribution, Unique and Shared Epitopes, and Predictive Autoantibodies

  1997cites this paper
• Genetic polymorphism of human CYP2E1: characterization of two variant alleles.

  1997cites this paper
• Baculovirus expression and purification of human and rat cytochrome P450 2E1.

  1996cites this paper
• Sex-dependent pharmacokinetics of indinavir: in vivo and in vitro evidence.

  1996cites this paper
• Perinatal Regulation of a Novel Mouse Cytochrome P450 Induced by Pregnancy

  1995cites this paper
• Induction of cytochrome P-450 isoenzymes in cultured monkey hepatocytes.

  1995cites this paper
• Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).

  1995cites this paper
• Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.

  1995cites this paper
• [Molecular toxicology of cytochrome P450: focusing on interspecies homology].

  1995cites this paper
• Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.

  1995cites this paper
• Evidence for the existence of two human CYP2E1 cDNAs using different polyadenylation signals.

  1995cites this paper
• Molecular cloning and functional expression of a mouse cytochrome P-450 (Cyp3a-13): examination of Cyp3a-13 enzyme to activate aflatoxin B1 (AFB1).

  1994cites this paper
• Purification and characterization of cytochrome P450 3A enzyme from hepatic microsomes of untreated doguera baboons.

  1994cites this paper
• Characterization of monkey cytochrome P450, P450 CMLd, responsible for S-mephenytoin 4-hydroxylation in hepatic microsomes of cynomolgus monkeys.

  1994cites this paper
• A comparative study of constitutive and induced alkoxyresorufin O-dealkylation and individual cytochrome P450 forms in cynomolgus monkey (Macaca fascicularis), human, mouse, rat and hamster liver microsomes.

  1994cites this paper
• Molecular cloning and sequence analysis of hamster CYP2E1.

  1994cites this paper
• Induction of drug metabolizing enzymes by polychlorinated biphenyl in the parotid gland and relation to changes in vitamin A content and morphological changes.

  1994cites this paper
• A novel form of mouse cytochrome P450 3A (Cyp3a-16). Its cDNA cloning and expression in fetal liver.

  1994cites this paper
• Purification and characterization of two forms of hepatic microsomal cytochrome P450 from untreated cynomolgus monkeys.

  1993cites this paper
• Characterization of cytochrome P-450 2B6 in human liver microsomes.

  1993cites this paper
• The P450 Superfamily: Update on New Sequences, Gene Mapping, and Recommended Nomenclature

  1991cites this paper