Retroevolution of lambda Cro toward a stable monomer.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 12598646PMCID PMC151343
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fold change in evolution of protein structures.

  2001cited by this paper
• Coupled energetics of lambda cro repressor self-assembly and site-specific DNA operator binding I: analysis of cro dimerization from nanomolar to micromolar concentrations.

  2000cited by this paper
• An evolutionary bridge to a new protein fold

  2000cited by this paper
• Thermodynamic analysis of the structural stability of phage 434 Cro protein.

  1999cited by this paper
• A thermodynamic study of the 434-repressor N-terminal domain and of its covalently linked dimers.

  1999cited by this paper
• Evolution of a protein fold in vitro.

  1999cited by this paper
• Refined structure of Cro repressor protein from bacteriophage lambda suggests both flexibility and plasticity.

  1998cited by this paper
• Crystal structure of an engineered cro monomer bound nonspecifically to DNA: Possible implications for nonspecific binding by the wild‐type protein

  1998cited by this paper
• How far divergent evolution goes in proteins.

  1998cited by this paper
• Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution.

  1998cited by this paper
• Three-dimensional solution structure and stability of phage 434 Cro protein.

  1997cited by this paper
• A folded monomeric intermediate in the formation of lambda Cro dimer-DNA complexes.

  1997cited by this paper
• Heat and cold denatured states of monomeric lambda repressor are thermodynamically and conformationally equivalent.

  1996cited by this paper
• Three-dimensional dimer structure of the lambda-Cro repressor in solution as determined by heteronuclear multidimensional NMR.

  1995cited by this paper
• Structure and stability of monomeric lambda repressor: NMR evidence for two-state folding.

  1995cited by this paper
• One-step evolution of a dimer from a monomeric protein

  1995cited by this paper
• Determination of the nuclear magnetic resonance structure of the DNA-binding domain of the P22 c2 repressor (1 to 76) in solution and comparison with the DNA-binding domain of the 434 repressor.

  1994cited by this paper
• P22 Arc repressor: Enhanced expression of unstable mutants by addition of polar C‐terminal sequences

  1993cited by this paper
• Refined 1.8 A crystal structure of the lambda repressor-operator complex.

  1992cited by this paper
• Determination of the nuclear magnetic resonance solution structure of the DNA-binding domain (residues 1 to 69) of the 434 repressor and comparison with the X-ray crystal structure.

  1992cited by this paper
• Different interactions of Cro repressor dimer with the left and right halves of OR3 operator DNA.

  1991cited by this paper
• The phage 434 Cro/OR1 complex at 2.5 A resolution.

  1991cited by this paper
• Stable, monomeric variants of lambda Cro obtained by insertion of a designed beta-hairpin sequence.

  1990cited by this paper
• Structure of the amino-terminal domain of phage 434 repressor at 2.0 A resolution.

  1989cited by this paper
• Structure of phage 434 Cro protein at 2.35 A resolution.

  1989cited by this paper
• Amino acid substitutions that increase the thermal stability of the lambda Cro protein.

  1989cited by this paper
• Structure of a phage 434 Cro/DNA complex

  1988cited by this paper
• Structure of the represser–operator complex of bacteriophage 434

  1987cited by this paper
• Dimerization of the operator binding domain of phage lambda repressor.

  1987cited by this paper
• Bacteriophage P22 Cro protein: sequence, purification, and properties.

  1986cited by this paper
• The operator-binding domain of lambda repressor: structure and DNA recognition.

  1982cited by this paper
• Areas, volumes, packing and protein structure.

  1977cited by this paper

• In silico insights into the dimer structure and deiodinase activity of type III iodothyronine deiodinase from bioinformatics, molecular dynamics simulations, and QM/MM calculations

  2022cites this paper
• A high‐throughput predictive method for sequence‐similar fold switchers

  2021cites this paper
• Extreme divergence between one-to-one orthologs: the structure of N15 Cro bound to operator DNA and its relationship to the λ Cro complex

  2019cites this paper
• Multistep mutational transformation of a protein fold through structural intermediates

  2018cites this paper
• Foldability of a Natural De Novo Evolved Protein.

  2017cites this paper
• Studying protein fold evolution with hybrids of differently folded homologs.

  2015cites this paper
• Substrate-Induced Dimerization of Engineered Monomeric Variants of Triosephosphate Isomerase from Trichomonas vaginalis

  2015cites this paper
• Antibody repertoire deep sequencing reveals antigen-independent selection in maturing B cells

  2014cites this paper
• Structural and thermodynamic folding characterization of triosephosphate isomerases from Trichomonas vaginalis reveals the role of destabilizing mutations following gene duplication

  2014cites this paper
• Controlling Allosteric Networks in Proteins.

  2013cites this paper
• Observed octameric assembly of a Plasmodium yoelii peroxiredoxin can be explained by the replacement of native “ball‐and‐socket” interacting residues by an affinity tag

  2013cites this paper
• A role for indels in the evolution of Cro protein folds

  2013cites this paper
• Protein Dimerization and Oligomerization in Biology

  2012cites this paper
• The relationship between oligomeric state and protein function.

  2012cites this paper
• Measuring 1HN temperature coefficients in invisible protein states by relaxation dispersion NMR spectroscopy

  2011cites this paper
• Evolutionary bridges to new protein folds: design of C-terminal Cro protein chameleon sequences.

  2011cites this paper
• Determinants of gas-phase disassembly behavior in homodimeric protein complexes with related yet divergent structures.

  2011cites this paper
• Reengineering Cro protein functional specificity with an evolutionary code.

  2011cites this paper
• Biochemical Characterization of the Transcriptional Regulator BzdR from Azoarcus sp. CIB*

  2010cites this paper
• A simple method for measuring signs of 1HN chemical shift differences between ground and excited protein states

  2010cites this paper
• Mécanismes de transposition et de régulation de la transposase de l'élément mariner Mos1

  2009cites this paper
• Cross-Over between Discrete and Continuous Protein Structure Space: Insights into Automatic Classification and Networks of Protein Structures

  2009cites this paper
• Effect of interdomain linker length on an antagonistic folding-unfolding equilibrium between two protein domains.

  2009cites this paper
• Moderately thermostable phage Phi11 Cro repressor has novel DNA-binding capacity and physicochemical properties.

  2009cites this paper
• Functional Adhesiveness of the CX3CL1 Chemokine Requires Its Aggregation

  2008cites this paper
• Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds

  2008cites this paper
• Two structures of a lambda Cro variant highlight dimer flexibility but disfavor major dimer distortions upon specific binding of cognate DNA.

  2008cites this paper
• PROTEIN DESIGNABILITY AND ENGINEERING

  2008cites this paper
• N15 Cro and λ Cro: Orthologous DNA‐binding domains with completely different but equally effective homodimer interfaces

  2008cites this paper
• A quantitative study of lambda-phage SWITCH and its components.

  2007cites this paper
• A Quantitative Study of l -Phage SWITCH and Its Components

  2007influential citation
• Role of the lytic repressor in prophage induction of phage lambda as analyzed by a module-replacement approach.

  2006cites this paper
• Relationship between sequence determinants of stability for two natural homologous proteins with different folds.

  2006cites this paper
• A trade between similar but nonequivalent intrasubunit and intersubunit contacts in Cro dimer evolution.

  2006cites this paper
• Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping.

  2005cites this paper
• A survey of flexible protein binding mechanisms and their transition states using native topology based energy landscapes.

  2005cites this paper
• Switches in bacteriophage lambda development.

  2005cites this paper
• Mariner Mos1 transposase dimerizes prior to ITR binding.

  2005cites this paper
• A novel member of the YchN‐like fold: Solution structure of the hypothetical protein Tm0979 from Thermotoga maritima

  2005cites this paper
• Genome sequence of bacteriophage ΦAR29: a basis for integrative plasmid vectors

  2005cites this paper
• Positive Autoregulation of cI Is a Dispensable Feature of the Phage λ Gene Regulatory Circuitry

  2005cites this paper
• Assembly of the mariner Mos1 Synaptic Complex

  2005cites this paper
• Positive autoregulation of cI is a dispensable feature of the phage lambda gene regulatory circuitry.

  2005cites this paper
• Secondary structure switching in Cro protein evolution.

  2004cites this paper
• Repertoire selection of variant single-chain Cro: toward directed DNA-binding specificity of helix-turn-helix proteins.

  2004cites this paper