Comparative p53 mutational analysis of multiple primary cancers of the upper aerodigestive tract.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Surgery

• Publication date

  1996-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0039-6060(96)80240-6PMID 8693422
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1988cited by this paper
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  1980cited by this paper
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  1946cited by this paper
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  1946cited by this paper
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