Lung-specific induction of heme oxygenase-1 and hyperoxic lung injury.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  American Journal of Physiology

• Publication date

  1998-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1152/ajplung.1998.274.4.L582PMID 9575877
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural and biochemical changes in rat lungs occurring during exposures to lethal and adaptive doses of oxygen.

  2015cited by this paper
• Hypothesis: Iron chelation plays a vital role in neutrophilic inflammation

  1997cited by this paper
• Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury.

  1996cited by this paper
• Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury.

  1996cited by this paper
• Differences in basal and hyperoxia-associated HO expression in oxidant-resistant hamster fibroblasts.

  1996cited by this paper
• Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia.

  1996cited by this paper
• Acquired resistance to acute oxidative stress. Possible role of heme oxygenase and ferritin.

  1995cited by this paper
• Endothelial cell heme oxygenase and ferritin induction in rat lung by hemoglobin in vivo.

  1995influential reference
• Induction of heme oxygenase in toxic renal injury: a protective role in cisplatin nephrotoxicity in the rat.

  1995cited by this paper
• Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1.

  1995influential reference
• Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity.

  1995cited by this paper
• Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts.

  1994cited by this paper
• Heme oxygenase does not protect human cells against oxidant stress.

  1994cited by this paper
• Heme oxygenase does not protect human cells against oxidant stress.

  1994cited by this paper
• Measurement of plasma hydroperoxide concentrations by the ferrous oxidation-xylenol orange assay in conjunction with triphenylphosphine.

  1994cited by this paper
• Tolerance of rats to hyperoxia. Lung antioxidant enzyme gene expression.

  1993cited by this paper
• Lipid peroxidation: its mechanism, measurement, and significance.

  1993cited by this paper
• Induction of heme oxygenase is a rapid, protective response in rhabdomyolysis in the rat.

  1992cited by this paper
• Ferritin: a cytoprotective antioxidant strategem of endothelium.

  1992cited by this paper
• Role of inflammatory cells in the metabolic activation of polycyclic aromatic hydrocarbons in mouse skin.

  1987cited by this paper
• Bilirubin is an antioxidant of possible physiological importance.

  1987cited by this paper
• Protection against lethal hyperoxia by tracheal insufflation of erythrocytes: role of red cell glutathione.

  1985cited by this paper
• Free radicals in biology and medicine

  1985influential reference
• Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker.

  1982cited by this paper
• Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

  1979cited by this paper
• Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

  1979cited by this paper
• Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism.

  1971cited by this paper
• Microsomal heme oxygenase. Characterization of the enzyme.

  1969cited by this paper
• The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

  1968cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Transcriptional Regulation of HMOX1 Gene in Hezuo Tibetan Pigs: Roles of WT1, Sp1, and C/EBPα

  2020cites this paper
• Association of Nrf2 with airway pathogenesis: lessons learned from genetic mouse models

  2015cites this paper
• Tissue heme oxygenase-1 exerts anti-inflammatory effects on LPS-induced pulmonary inflammation

  2015cites this paper
• Effects of Two Different Exogenous Surfactant Preparations on Serial Peripheral Perfusion Index and Tissue Carbon Monoxide Measurements in Preterm Infants with Severe Respiratory Distress Syndrome.

  2015cites this paper
• The role of red blood cells and cell-free hemoglobin in the pathogenesis of ARDS

  2015cites this paper
• Suppression of heme oxygenase-1 activity reduces airway hyperresponsiveness and inflammation in a mouse model of asthma

  2015cites this paper
• Intranasal administration with recombinant Lactococcus lactis expressing heme oxygenase-1 reduces hyperoxia-induced lung inflammation in rat pups

  2015cites this paper
• Anti-Inflammatory and Cell Signalling Effects of Biliverdin and Biliverdin Reductase

  2014cites this paper
• Suppression of inflammatory cell trafficking and alveolar simplification by the heme oxygenase-1 product carbon monoxide.

  2014cites this paper
• Inhibitory Effects of Palm Tocotrienol-Rich Fraction Supplementation on Bilirubin-Metabolizing Enzymes in Hyperbilirubinemic Adult Rats

  2014cites this paper
• Heme oxygenase-1 attenuates acute pulmonary inflammation by decreasing the release of segmented neutrophils from the bone marrow.

  2014cites this paper
• Unraveling the Role of Hemeoxygenase-1/Carbon Monoxide in Pulmonary and Cardiovascular Diseases.

  2013cites this paper
• Epithelium from Oxidant-Mediated Death Lung Injury by Protecting the Alveolar TLR Signaling Prevents Hyperoxia-Induced

  2012cites this paper
• TLR Signaling Prevents Hyperoxia-Induced Lung Injury by Protecting the Alveolar Epithelium from Oxidant-Mediated Death

  2012cites this paper
• Isoflurane Preconditioning at Clinically Relevant Doses Induce Protective Effects of Heme Oxygenase-1 on Hepatic Ischemia Reperfusion in Rats

  2011cites this paper
• Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system

  2011cites this paper
• Expression of haem oxygenase-1 and inducible nitric oxide synthase in horses with lower airway inflammation

  2011cites this paper
• Nrf2 protects against airway disorders.

  2010cites this paper
• Heme Oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome

  2009cites this paper
• Ischemia/reperfusion Lung Injury Increases Serum Ferritin and Heme Oxygenase-1 in Rats.

  2009cites this paper
• Genetic ablation of the Bach1 gene reduces hyperoxic lung injury in mice: role of IL-6.

  2009cites this paper
• A Phosphodiesterase III Inhibitor Protects Rat Liver From Sinusoidal Obstruction Syndrome Through Heme Oxygenase-1 Induction

  2009cites this paper
• Mitochondrial Biogenesis in the Pulmonary Vasculature During Inhalational Lung Injury and Fibrosis

  2008influential citation
• Similar but not the same: normobaric and hyperbaric pulmonary oxygen toxicity, the role of nitric oxide.

  2007cites this paper
• Repopulation genetisch veränderter Kupffer-Zellen und Evaluation deren Effekte in einem akuten hepatischen Schädigungsmodell

  2007influential citation
• Genetic mechanisms of susceptibility to oxidative lung injury in mice.

  2007cites this paper
• Heme, Heme Oxygenase, and Ferritin: How the Vascular Endothelium Survives (and Dies) in an Iron-Rich Environment

  2007cites this paper
• VEGF‐induced heme oxygenase‐1 confers cytoprotection from lethal hyperoxia in vivo

  2007cites this paper
• Heme Oxygenase-1 : A Multifaceted Triple-Threat Molecule The Role of Heme Oxygenase-1 in Pulmonary Disease

  2007cites this paper
• oxygen toxicity—the role of nitric oxide

  2007cites this paper
• Dual Role of VEGF-Induced Heme-Oxygenase-1 in Angiogenesis

  2006cites this paper
• (CAVEOLIN-1: A CRITICAL REGULATOR OF INFLAMMATION AND FIBROSIS)

  2006cites this paper
• Monóxido de carbono: dos caras de un mismo personaje

  2006cites this paper
• Oxidant and antioxidant balance in the airways and airway diseases.

  2006cites this paper
• Nrf2 Defends the Lung from Oxidative Stress

  2006cites this paper
• [Carbon monoxide: two sides to the same coin].

  2006cites this paper
• Heme oxygenase-1 expression in disease states.

  2005cites this paper
• Differential effects of anesthetics on endotoxin-induced liver injury.

  2005cites this paper
• Cytoprotection of heme oxygenase-1/carbon monoxide in lung injury.

  2005cites this paper
• State of the Art Heme Oxygenase-1 From Bench to Bedside

  2005cites this paper
• Heme oxygenase-1: from bench to bedside.

  2005cites this paper
• Prevention of hemorrhagic shock-induced lung injury by heme arginate treatment in rats.

  2005cites this paper
• Lung heme oxygenase-1 is elevated in acute respiratory distress syndrome

  2004cites this paper
• Heme oxygenase does not contribute to control of basal vascular tone in isolated blood-perfused rat lung.

  2004cites this paper
• HEME OXYGENASE-1 MEDIATED CYTOPROTECTION IN ACUTE LUNG INJURY

  2004cites this paper
• Heme Oxygenase-1 and Transplantation

  2004cites this paper
• Analysis of pulmonary heme oxygenase-1 and nitric oxide synthase alterations in experimental hepatopulmonary syndrome.

  2003cites this paper
• Preconditioning with tin-protoporphyrin IX attenuates ischemia/reperfusion injury in the rat kidney.

  2003influential citation
• Heme oxygenase-1: unleashing the protective properties of heme.

  2003cites this paper
• Investigations on the mechanism of hyperbaric oxygen (HBO)-induced adaptive protection against oxidative stress.

  2002cites this paper
• Up-regulation of heme oxygenase-I in alveolar macrophages of newly diagnosed asthmatics.

  2002cites this paper
• EXPRESSION OF OXIDANT AND ANTIOXIDANT ENZYMES IN HUMAN LUNG AND INTERSTITIAL LUNG DISEASES

  2002cites this paper
• Selective Regulation of Blood Pressure by Heme Oxygenase-1 in Hypertension

  2002cites this paper
• Pro-oxidant and cytotoxic effects of circulating heme.

  2002cites this paper
• Données actuelles sur la toxicité de l’oxygène

  2002cites this paper
• Carbon monoxide promotes hypoxic pulmonary vascular remodeling.

  2002cites this paper
• Expression and regulation of hemeoxygenase 1 in healthy human lung and interstitial lung disorders.

  2001cites this paper
• Effect of nitric oxide on shock‐induced hepatic heme oxygenase‐1 expression in the rat

  2001cites this paper
• Inhaled carbon monoxide and hyperoxic lung injury in rats.

  2001cites this paper
• Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

  2001cites this paper
• Increased expression of heme oxygenase (HO)-1 in alveolar spaces and HO-2 in alveolar walls of smokers.

  2001cites this paper
• Iron signalling regulated directly and through oxygen: implications for sepsis and the acute respiratory distress syndrome.

  2001cites this paper
• Expression of heme oxygenase in human airway epithelial cells.

  2001cites this paper
• Renal vasodilatory influence of endogenous carbon monoxide in chronically hypoxic rats.

  2000cites this paper
• Involvement of haemoxygenase-1 in ozone-induced airway inflammation and hyperresponsiveness.

  2000cites this paper
• Heme oxygenase: colors of defense against cellular stress.

  2000cites this paper
• Tin-protoporphyrin potentiates arsenite-induced DNA strand breaks, chromatid breaks and kinetochore-negative micronuclei in human fibroblasts.

  2000cites this paper
• Effects of hemoglobin on heme oxygenase gene expression and viability of cultured smooth muscle cells.

  2000cites this paper
• Signal transduction pathways in hyperoxia-induced lung cell death.

  2000cites this paper
• HO-1 expression in type II pneumocytes after transpulmonary gene delivery.

  2000cites this paper
• Ferriporphyrins and endothelium: a 2-edged sword-promotion of oxidation and induction of cytoprotectants.

  2000cites this paper
• Oxygen Therapy in Intensive Care Patients: A Vital Poison?

  1999cites this paper
• Protective effects of heme oxygenase-1 against oxidant-induced injury in the cultured human tracheal epithelium.

  1999cites this paper
• Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury.

  1999cites this paper
• Protective effects of heme oxygenase-1 in acute lung injury.

  1999cites this paper
• Heme Oxygenase and Acute Lung Injury: The Functional Significance of Heme Oxygenase Induction

  1999cites this paper
• Iron overload upregulates haem oxygenase 1 in the lung more rapidly than in other tissues

  1999cites this paper
• Haem oxygenase shows pro-oxidant activity in microsomal and cellular systems: implications for the release of low-molecular-mass iron.

  1999cites this paper
• Introduction: Acute Lung Injury

  1999cites this paper
• Induction of ferritin and heme oxygenase-1 by endotoxin in the lung.

  1998cites this paper
• Effects of Two Different Exogenous Surfactant Preparations on Serial Peripheral Perfusion Index and Tissue Carbon Monoxide Measurements in Preterm Infants with Severe Respiratory Distress Syndrome y

  year unknowncites this paper