An ultra-low dose of tetrahydrocannabinol provides cardioprotection.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Biochemical Pharmacology

• Publication date

  2013-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bcp.2013.03.014PMID 23537701
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Long-term behavioral and biochemical effects of an ultra-low dose of Δ9-tetrahydrocannabinol (THC): neuroprotection and ERK signaling

  2012cited by this paper
• Pre- and post-conditioning treatment with an ultra-low dose of Δ9-tetrahydrocannabinol (THC) protects against pentylenetetrazole (PTZ)-induced cognitive damage.

  2011cited by this paper
• A physiological concentration of glucocorticoid inhibits the pro‐inflammatory cytokine‐induced proliferation of adult rat cardiac fibroblasts: Roles of extracellular signal‐regulated kinase 1/2 and nuclear factor‐κB

  2011cited by this paper
• Reperfusion Injury Salvage Kinase and Survivor Activating Factor Enhancement Prosurvival Signaling Pathways in Ischemic Postconditioning: Two Sides of the Same Coin

  2011cited by this paper
• Themed Issue: Cannabinoids in Biology and Medicine, Part I

  2011cited by this paper
• When are pro-inflammatory cytokines SAFE in heart failure?

  2011cited by this paper
• UTP reduces infarct size and improves mice heart function after myocardial infarct via P2Y2 receptor.

  2011cited by this paper
• Acute administration of cannabidiol in vivo suppresses ischaemia‐induced cardiac arrhythmias and reduces infarct size when given at reperfusion

  2010cited by this paper
• CB(2) cannabinoid receptor activation is cardioprotective in a mouse model of ischemia/reperfusion.

  2009cited by this paper
• Activation of the protective Survivor Activating Factor Enhancement (SAFE) pathway against reperfusion injury: Does it go beyond the RISK pathway?

  2009cited by this paper
• Preconditioning and postconditioning: underlying mechanisms and clinical application.

  2009cited by this paper
• The cannabinoid receptor type 2 promotes cardiac myocyte and fibroblast survival and protects against ischemia/reperfusion‐induced cardiomyopathy

  2009cited by this paper
• The immune system and cardiac repair.

  2008cited by this paper
• Role of cannabinoid receptors in regulation of cardiac tolerance to ischemia and reperfusion

  2008cited by this paper
• Endocannabinoids and cannabinoid receptors in ischaemia–reperfusion injury and preconditioning

  2008cited by this paper
• Bax deficiency reduces infarct size and improves long-term function after myocardial infarction

  2007cited by this paper
• Cannabidiol, a nonpsychoactive Cannabis constituent, protects against myocardial ischemic reperfusion injury.

  2007cited by this paper
• Endothelial CB1-receptors limit infarct size through NO formation in rat isolated hearts.

  2007cited by this paper
• Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia via CB2 receptor activation and nitric oxide production

  2006cited by this paper
• Ischemic preconditioning-induced activation of ERK1/2 in the rat hippocampus.

  2006cited by this paper
• Cannabinoid CB2 receptor activation reduces mouse myocardial ischemia‐reperfusion injury: involvement of cytokine/chemokines and PMN

  2004cited by this paper
• Endocannabinoids protect the rat isolated heart against ischaemia

  2003cited by this paper
• Preconditioning the myocardium: from cellular physiology to clinical cardiology.

  2003cited by this paper
• Bax ablation protects against myocardial ischemia-reperfusion injury in transgenic mice.

  2003cited by this paper
• Contribution of endocannabinoids in the endothelial protection afforded by ischemic preconditioning in the isolated rat heart.

  2003cited by this paper
• Activation of Cannabinoid Receptors Decreases the Area of Ischemic Myocardial Necrosis

  2002cited by this paper
• Extracellular signal-regulated kinase and c-Jun N-terminal protein kinase in ischemic tolerance

  2001cited by this paper
• Activation of Type II Cannabinoid Receptors Improves Myocardial Tolerance to Arrhythmogenic Effects of Coronary Occlusion and Reperfusion

  2001cited by this paper
• Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice.

  2000cited by this paper
• Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs.

  2000cited by this paper
• Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study.

  1997cited by this paper
• Mortality by cause for eight regions of the world: Global Burden of Disease Study

  1997cited by this paper
• Development of cell injury in sustained acute ischemia.

  1990cited by this paper
• Sarcoplasmic reticulum function in the "stunned" myocardium.

  1989cited by this paper
• Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

  1986cited by this paper

• Unmasking the cannabis paradox: in-hospital outcomes of cannabis users admitted with acute myocardial infarction over a 20-year period in the United States

  2024cites this paper
• Phytocannabinoids as Chemotherapy Adjuncts—A Review for Users

  2024cites this paper
• Re-evaluation of the cardioprotective effects of cannabinoids against ischemia-reperfusion injury according to the IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria

  2024cites this paper
• Cardiotoxic effects of common and emerging drugs: role of cannabinoid receptors.

  2024cites this paper
• How do phytocannabinoids affect cardiovascular health? An update on the most common cardiovascular diseases

  2023cites this paper
• Effects of Δ9-Tetrahydrocannabinol and the Aminoalkylindole K2/Spice Constituent JWH-073 on Cardiac Tissue and Mesenteric Vascular Reactivity

  2023cites this paper
• Why Do Marijuana and Synthetic Cannabimimetics Induce Acute Myocardial Infarction in Healthy Young People?

  2022cites this paper
• Δ9-cis-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology.

  2021cites this paper
• Pharmacological Properties of the Plant-Derived Natural products Cannabinoids and Implications for Cardiovascular Health.

  2021cites this paper
• Applications of Cannabis Sativa L. in Food and Its Therapeutic Potential: From a Prohibited Drug to a Nutritional Supplement

  2021cites this paper
• Cannabis, e-cigarettes and anesthesia.

  2020cites this paper
• Cannabinoid-sensitive receptors in cardiac physiology and ischaemia.

  2020cites this paper
• Pharmacology of Endocannabinoids and Their Receptors

  2020cites this paper
• Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol.

  2019cites this paper
• The Role of Heme Oxygenase 1 in the Protective Effect of Caloric Restriction against Diabetic Cardiomyopathy

  2019cites this paper
• Cannabinoid CB_1 and CB_2 receptors antagonists AM251 and AM630 differentially modulate the chronotropic and inotropic effects of isoprenaline in isolated rat atria

  2019cites this paper
• Beneficial and deleterious effects of cannabinoids in the brain: the case of ultra-low dose THC

  2019cites this paper
• Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly

  2018cites this paper
• Regulation of diabetic cardiomyopathy by caloric restriction is mediated by intracellular signaling pathways involving ‘SIRT1 and PGC-1α’

  2018cites this paper
• PARP‐1 inhibition protects the diabetic heart through activation of SIRT1‐PGC‐1&agr; axis☆

  2018cites this paper
• Uncovering the psychoactivity of a cannabinoid from liverworts associated with a legal high

  2018cites this paper
• The Role of Δ9-Tetrahydrocannabinol in Diabetes Mellitus

  2017cites this paper
• The current status of artisanal cannabis for the treatment of epilepsy in the United States.

  2017cites this paper
• Caloric restriction ameliorates cardiomyopathy in animal model of diabetes

  2017cites this paper
• Role of cannabis in cardiovascular disorders.

  2017cites this paper
• The Psychoneuroimmunological Influences of Recreational Marijuana

  2017cites this paper
• Cannabinoid CB1/CB2 Receptors in the Heart: Expression, Regulation, and Function

  2016cites this paper
• From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology.

  2016cites this paper
• Coronary thrombosis and marijuana smoking: a case report and narrative review of the literature.

  2016cites this paper
• Complications vasculaires périphériques, cardiaques et cérébrales associées à l’utilisation du cannabis

  2016cites this paper
• Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction

  2016cites this paper
• Prospects for Creation of Cardioprotective Drugs Based on Cannabinoid Receptor Agonists

  2016cites this paper
• Cannabinoids Production by Hairy Root Cultures of Cannabis sativa L.

  2015cites this paper
• Copyright Medinews (Cardiology) Limited Reproduction Prohibited Copyright Medinews (Cardiology) Limited Reproduction Prohibited Copyright Medinews (Cardiology) Limited Reproduction Prohibited Copyright Medinews (Cardiology) Limited Reproduction Prohibited Synthetic and natural cannabinoids: the card

  2015cites this paper
• A labdane diterpene exerts ex vivo and in vivo cardioprotection against post-ischemic injury: involvement of AKT-dependent mechanisms.

  2015cites this paper
• Long-Lived αMUPA Mice Show Attenuation of Cardiac Aging and Leptin-Dependent Cardioprotection

  2015influential citation
• Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury

  2015cites this paper
• A new face of endocannabinoids in pharmacotherapy. Part I: protective role of endocannabinoids in hypertension and myocardial infarction.

  2014cites this paper
• Biochemical and immunohistochemical changes in delta-9-tetrahydrocannabinol-treated type 2 diabetic rats.

  2014influential citation
• Ultralow doses of cannabinoid drugs protect the mouse brain from inflammation‐induced cognitive damage

  2014cites this paper
• HORMESIS EFFECT AND THE INFLUENCE OF ULTRA-LOW GLYCOSIDES DOSES ON THE BONE MARROW CELLS PROLIFERATIVE ACTIVITY

  year unknowncites this paper