Early communication deficits in the Shank1 knockout mouse model for autism spectrum disorder: Developmental aspects and effects of social context

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Autism Research

• Publication date

  2016-06-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1002/aur.1564PMID 26419918
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism

  2015cited by this paper
• Mice lacking the cerebral cortex develop normal song: Insights into the foundations of vocal learning

  2015cited by this paper
• Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear.

  2015cited by this paper
• Reduced isolation-induced pup ultrasonic communication in mouse pups lacking brain serotonin

  2015cited by this paper
• Shank mutant mice as an animal model of autism

  2014cited by this paper
• The emerging role of SHANK genes in neuropsychiatric disorders

  2014cited by this paper
• Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.

  2014cited by this paper
• Ultrasonic vocalizations in Shank mouse models for autism spectrum disorders: detailed spectrographic analyses and developmental profiles.

  2014influential reference
• Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: developmental aspects and effects of social context.

  2014cited by this paper
• De novo mutations in schizophrenia implicate synaptic networks

  2014cited by this paper
• Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

  2014influential reference
• Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

  2013cited by this paper
• Monogenic mouse models of social dysfunction: implications for autism.

  2013cited by this paper
• Behavioural methods used in rodent models of autism spectrum disorders: current standards and new developments.

  2013cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders

  2013cited by this paper
• The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers.

  2013cited by this paper
• The Autism ProSAP1/Shank2 mouse model displays quantitative and structural abnormalities in ultrasonic vocalisations.

  2013influential reference
• Modeling autism by SHANK gene mutations in mice.

  2013cited by this paper
• Mouse vocal communication system: are ultrasounds learned or innate?

  2013cited by this paper
• Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

  2012influential reference
• BTBR T+tf/J mice: autism-relevant behaviors and reduced fractone-associated heparan sulfate.

  2012cited by this paper
• Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent Shank3 Null Mutant Mice

  2012cited by this paper
• A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis

  2012cited by this paper
• SHANK1 Deletions in Males with Autism Spectrum Disorder.

  2012influential reference
• Cellular and synaptic network defects in autism.

  2012cited by this paper
• Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor.

  2012cited by this paper
• Mice do not require auditory input for the normal development of their ultrasonic vocalizations

  2012cited by this paper
• Functional consequences of mutations in postsynaptic scaffolding proteins and relevance to psychiatric disorders.

  2012cited by this paper
• Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

  2012cited by this paper
• Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

  2012cited by this paper
• The autism diagnosis in translation: shared affect in children and mouse models of ASD

  2011cited by this paper
• Maternal care differs in mice bred for high vs. low trait anxiety: Impact of brain vasopressin and cross-fostering

  2011cited by this paper
• Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior

  2011influential reference
• Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

  2011cited by this paper
• Evo-devo, deep homology and FoxP2: implications for the evolution of speech and language

  2011cited by this paper
• Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.

  2011influential reference
• Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication

  2011cited by this paper
• Sociability and motor functions in Shank1 mutant mice.

  2011influential reference
• Lay abstracts

  2011cited by this paper
• Behavioural phenotyping assays for mouse models of autism

  2010cited by this paper
• Functional impact of global rare copy number variation in autism spectrum disorders

  2010influential reference
• Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

  2010influential reference
• Social cognition and the evolution of language: constructing cognitive phylogenies.

  2010cited by this paper
• Novel de novo SHANK3 mutation in autistic patients

  2009influential reference
• A synaptic trek to autism.

  2009cited by this paper
• Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders.

  2009cited by this paper
• Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

  2008influential reference
• Effects of Genetic Background, Gender, and Early Environmental Factors on Isolation-Induced Ultrasonic Calling in Mouse Pups: An Embryo-Transfer Study

  2008cited by this paper
• Minimal aberrant behavioral phenotypes of neuroligin‐3 R451C knockin mice

  2008cited by this paper
• Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism

  2008cited by this paper
• Maternal care, isolation-induced infant ultrasonic calling, and their relations to adult anxiety-related behavior in the rat.

  2008cited by this paper
• Contribution of SHANK3 mutations to autism spectrum disorder.

  2007cited by this paper
• Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

  2007cited by this paper
• Contribution of SHANK 3 Mutations to Autism Spectrum Disorder

  2007cited by this paper
• PDZ domain proteins of synapses

  2004influential reference
• Ultraschall-Laute bei jungen Mäusen

  2004cited by this paper
• Terminal 22q deletion syndrome: a newly recognized cause of speech and language disability in the autism spectrum.

  2004cited by this paper
• Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor Gene

  2004cited by this paper
• Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

  2003cited by this paper
• Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth

  2002cited by this paper
• 22q13 deletion syndrome.

  2001cited by this paper
• Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome.

  2001cited by this paper
• A clinical study of 57 children with fetal anticonvulsant syndromes

  2000cited by this paper
• Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin.

  1999cited by this paper
• Ultrasonic vocalizations by infant laboratory mice: a preliminary spectrographic characterization under different conditions.

  1998cited by this paper
• Aggression, anxiety and vocalizations in animals: GABAA and 5-HT anxiolytics

  1995cited by this paper
• Effects of age, sex, and odours from conspecific adult males on ultrasonic vocalizations of infant CS1 mice.

  1994cited by this paper
• Responses of infant mice to odors of urine from infanticidal, noninfanticidal, and paternal male mice.

  1990cited by this paper
• Chronic exposure to a novel odor increases pups' vocalizations, maternal care, and alters dopaminergic functioning in developing mice.

  1987cited by this paper
• Ultrasound recognition in house mice: Key-Stimulus configuration and recognition mechanism

  1982cited by this paper
• Ultrasounds in neonatal rats: novel, predator and conspecific odor cues.

  1982cited by this paper
• Neonatal ultrasounds elicited by odor cues.

  1978cited by this paper
• Responses of adult mice to models of infant calls.

  1976cited by this paper
• Ultrasonic Communication in Rodents

  1970cited by this paper
• CLINICAL STUDY The

  year unknowncited by this paper

• Unraveling mGluR5 dysfunction in autism spectrum disorder: a multi-level analysis of genetic, molecular, and neurobiological mechanisms.

  2026cites this paper
• Autism-Related Phenotypes in a Heterozygous Scn2aR854Q Mouse Model and Their Partial Rescue via a Potassium Channel Opener.

  2026cites this paper
• Potential Mechanism Connecting Preeclampsia to Autism Spectrum Disorder in Offspring: The Role of Microglial Abnormalities.

  2025cites this paper
• Tph2 deficiency leads to alterations in social adjustment and socio-affective communication in neonatal rats: No rescue effect of communal nesting.

  2025cites this paper
• Distinct early development trajectories in Nf1± and Tsc2± mouse models of autism

  2025cites this paper
• Methods for Assessing Neurodevelopmental Disorders in Mice: A Critical Review of Behavioral Tests and Methodological Considerations Searching to Improve Reliability

  2025cites this paper
• Developmental Disturbances in Animal Models of Autism Spectrum Disorder

  2025cites this paper
• Glutamate synaptic pathway plays an important role in neodymium oxide-incduced oxidative stress and inflammation of the brain

  2025cites this paper
• Involvement and regulation of the left anterior cingulate cortex in the ultrasonic communication deficits of autistic mice

  2024cites this paper
• Socio-affective communication in Tph2-deficient rat pups: communal nesting aggravates growth retardation despite ameliorating maternal affiliation deficits

  2024cites this paper
• Autistic‐relevant behavioral phenotypes of a mouse model of cyclin‐dependent kinase‐like 5 deficiency disorder

  2024cites this paper
• Gene Expression at the Tripartite Synapse: Bridging the Gap Between Neurons and Astrocytes.

  2024cites this paper
• Altered socio-affective communication and amygdala development in mice with protocadherin10-deficient interneurons

  2024influential citation
• Altered Socio-Affective Communication and Amygdala Development in mice with Protocadherin10-deficient Interneurons

  2024cites this paper
• Characterizing maternal isolation‐induced ultrasonic vocalizations in a gene–environment interaction rat model for autism

  2023cites this paper
• A review of ultrasonic vocalizations in mice and how they relate to human speech.

  2023cites this paper
• Mouse and rat ultrasonic vocalizations in neuroscience and neuropharmacology: State of the art and future applications

  2023cites this paper
• BAMBI: A new method for automated assessment of bidirectional early-life interaction between maternal behavior and pup vocalization in mouse dam-pup dyads

  2023cites this paper
• Prenatal low-dose methylmercury exposure causes premature neuronal differentiation and autism-like behaviors in a rodent model

  2023cites this paper
• Myt1l haploinsufficiency leads to obesity and multifaceted behavioral alterations in mice

  2022cites this paper
• Valproic acid exposure decreases neurogenic potential of outer radial glia in human brain organoids

  2022cites this paper
• Synaptic genes and neurodevelopmental disorders: From molecular mechanisms to developmental strategies of behavioral testing.

  2022cites this paper
• In utero exposure to cannabidiol disrupts select early-life behaviors in a sex-specific manner

  2022cites this paper
• Shank postsynaptic scaffolding proteins in autism spectrum disorder: mouse models and their dysfunctions in behaviors, synapses, and molecules.

  2022cites this paper
• Reconsidering animal models used to study autism spectrum disorder: Current state and optimizing future

  2022cites this paper
• Association of SHANK Family with Neuropsychiatric Disorders: An Update on Genetic and Animal Model Discoveries

  2021cites this paper
• Automatic classification of mice vocalizations using Machine Learning techniques and Convolutional Neural Networks

  2021cites this paper
• Lactobacillus reuteri effects on maternal separation stress in newborn mice

  2021cites this paper
• Vocal and physical phenotypes of calsyntenin2 knockout mouse pups model early-life symptoms of the autism spectrum disorder.

  2021cites this paper
• Communication and social interaction in the cannabinoid‐type 1 receptor null mouse: Implications for autism spectrum disorder

  2021influential citation
• Social behavior in prepubertal neurexin 1α deficient rats: A model of neurodevelopmental disorders.

  2021cites this paper
• Alteration of the Early Development Environment by Maternal Diet and the Occurrence of Autistic-like Phenotypes in Rat Offspring

  2021cites this paper
• Astroglia in Autism Spectrum Disorder

  2021cites this paper
• miR‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination

  2021cites this paper
• Ultrasonic vocalizations in mice: relevance for ethologic and neurodevelopmental disorders studies

  2020influential citation
• Assessing the developmental trajectory of mouse models of neurodevelopmental disorders: social and communication deficits in the Neurexin 1α Knockout Mouse

  2020cites this paper
• Behavioral neuroscience of autism.

  2020cites this paper
• Tau Reduction Prevents Key Features of Autism in Mouse Models.

  2020cites this paper
• Ultrasonic vocalizations as a fundamental tool for early and adult behavioral phenotyping of Autism Spectrum Disorder rodent models.

  2020cites this paper
• Effects of prenatal exposure to valproic acid or poly(I:C) on ultrasonic vocalizations in rat pups: the role of social cues.

  2020cites this paper
• Single cell 3’UTR analysis identifies changes in alternative polyadenylation throughout neuronal differentiation and in autism

  2020cites this paper
• Btbd3 expression regulates compulsive-like and exploratory behaviors in mice

  2019cites this paper
• Specific profile of ultrasonic communication in a mouse model of neurodevelopmental disorders

  2019cites this paper
• Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder

  2019cites this paper
• Assessing the developmental trajectory of mouse models of neurodevelopmental disorders: Social and communication deficits in mice with Neurexin 1α deletion

  2019cites this paper
• Translating preclinical findings in clinically relevant new antipsychotic targets: focus on the glutamatergic postsynaptic density. Implications for treatment resistant schizophrenia.

  2019cites this paper
• Ultrasonic vocalizations as a tool in studying emotional states in rodent models of social behavior and brain disease.

  2019cites this paper
• Cognitive impairment and autistic-like behaviour in SAPAP4-deficient mice

  2019cites this paper
• Social communication disorder: a narrative review on current insights

  2018cites this paper
• Social communication disorder: a narrative review on current insights

  2018cites this paper
• Social communication disorder: a narrative review on current insights

  2018cites this paper
• SHANK1 is differentially expressed during development in CA1 hippocampal neurons and astrocytes

  2018influential citation
• Computational Analysis of Neonatal Mouse Ultrasonic Vocalization

  2018cites this paper
• Rodent Vocalization Studies in Animal Models of the Autism Spectrum Disorder

  2018cites this paper
• Quantitative and Qualitative Features of Neonatal Vocalizations in Mice

  2018cites this paper
• Synaptopathology Involved in Autism Spectrum Disorder

  2018cites this paper
• A placental mammal‐specific microRNA cluster acts as a natural brake for sociability in mice

  2018cites this paper
• Reduced Efficacy of d-Amphetamine and 3,4-Methylenedioxymethamphetamine in Inducing Hyperactivity in Mice Lacking the Postsynaptic Scaffolding Protein SHANK1

  2018cites this paper
• Isolation‐induced ultrasonic vocalizations in pups: A comparison between Long‐Evans, Sprague–Dawley, and Wistar rats

  2018cites this paper
• Impaired Object Recognition but Normal Social Behavior and Ultrasonic Communication in Cofilin1 Mutant Mice

  2018cites this paper
• High-throughput mouse phenomics for characterizing mammalian gene function

  2018cites this paper
• 17-β estradiol increases parvalbumin levels in Pvalb heterozygous mice and attenuates behavioral phenotypes with relevance to autism core symptoms

  2018cites this paper
• Immunity and ultrasonic vocalization in rodents

  2018cites this paper
• Genetic variability in scaffolding proteins and risk for schizophrenia and autism-spectrum disorders: a systematic review.

  2018cites this paper
• Molecular basis of autism-like behavior in SAPAP3-deficient mice

  2017cites this paper
• Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post‐synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder

  2017cites this paper
• Altered ultrasonic vocalization in neonatal SAPAP3-deficient mice

  2017cites this paper
• Behavioral phenotypes and neurobiological mechanisms in the Shank1 mouse model for autism spectrum disorder: A translational perspective

  2017influential citation
• Relationship between ST8SIA2, polysialic acid and its binding molecules, and psychiatric disorders.

  2016cites this paper
• Genetic and non-genetic animal models for autism spectrum disorders (ASD).

  2016cites this paper