Src activation and translocation from focal adhesions to membrane ruffles contribute to formation of new adhesion sites

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Cellular and Molecular Life Sciences

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00018-008-8424-4PMID 19066724PMCID PMC11131495
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Src kinase activity and SH2 domain regulate the dynamics of Src association with lipid and protein targets

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• Src SH2 Arginine 175 Is Required for Cell Motility: Specific Focal Adhesion Kinase Targeting and Focal Adhesion Assembly Function

  2006cited by this paper
• Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreading.

  2006cited by this paper
• Two distinct pools of Src family tyrosine kinases regulate PDGF-induced DNA synthesis and actin dorsal ruffles

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• Tyrosine phosphatase SHP‐2 regulates IL‐1 signaling in fibroblasts through focal adhesions

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• The Src-Induced Mesenchymal State in Late-Stage Colon Cancer Cells

  2005cited by this paper
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  2005cited by this paper
• Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397

  2005cited by this paper
• Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior.

  2005cited by this paper
• Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization

  2004cited by this paper
• New insights into FAK signaling and localization based on detection of a FAT domain folding intermediate.

  2004cited by this paper
• The focal adhesion targeting domain of focal adhesion kinase contains a hinge region that modulates tyrosine 926 phosphorylation.

  2004cited by this paper
• Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C betaII are mediated by Src-family tyrosine kinases in porcine neutrophils.

  2004cited by this paper
• FAK–Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

  2004cited by this paper
• Src-Mediated Phosphorylation of Focal Adhesion Kinase Couples Actin and Adhesion Dynamics to Survival Signaling

  2004cited by this paper
• Periodic lamellipodial contractions correlate with rearward actin waves.

  2004cited by this paper
• Hierarchical assembly of cell-matrix adhesion complexes.

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• Targeting Membrane-localized Focal Adhesion Kinase to Focal Adhesions

  2003cited by this paper
• Src family kinases in tumor progression and metastasis

  2003cited by this paper
• v-Src Rescues Actin-based Cytoskeletal Architecture and Cell Motility and Induces Enhanced Anchorage Independence during Oncogenic Transformation of Focal Adhesion Kinase-null Fibroblasts*

  2003cited by this paper
• Differential regulation of cell motility and invasion by FAK

  2003cited by this paper
• Live-cell monitoring of tyrosine phosphorylation in focal adhesions following microtubule disruption

  2003cited by this paper
• Differential involvement of Src family kinases in pervanadate-mediated responses in rat myometrial cells.

  2002cited by this paper
• Src Catalytic but Not Scaffolding Function Is Needed for Integrin-Regulated Tyrosine Phosphorylation, Cell Migration, and Cell Spreading

  2002cited by this paper
• v-Src SH3-enhanced Interaction with Focal Adhesion Kinase at β1 Integrin-containing Invadopodia Promotes Cell Invasion*

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• Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity.

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  1999cited by this paper
• SH2- and SH3-mediated Interactions between Focal Adhesion Kinase and Src*

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  1998cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
• Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase.

  1992cited by this paper
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  1991cited by this paper
• Disintegration of adhesion plaques in chicken embryo fibroblasts upon Rous sarcoma virus-induced transformation: different dissociation rates for talin and vinculin.

  1990cited by this paper
• Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.

  1987cited by this paper
• Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src.

  1987cited by this paper

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