Cyclosporin A for Immunosuppression: Observations in Rat Heart, Pancreas, and Islet Allograft Models and in Human Renal and Pancreas Transplantation

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Diabetes

• Publication date

  1982-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2337/diab.31.4.S92PMID 6819969
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biological effects of cyclosporin A: A new antilymphocytic agent

  2005cited by this paper
• Technical aspects of segmental pancreatic grafting in rats

  1983cited by this paper
• Effect of cyclosporin A on allotransplanted pancreatic fragments to the spleen of totally pancreatectomized dogs.

  1982cited by this paper
• COMBINED IMMUNOSUPPRESSIVE THERAPY WITH CYCLOSPORIN A AND AZATHIOPRINE: A SYNERGISTIC EFFECT IN THREE OF FOUR EXPERIMENTAL MODELS

  1982cited by this paper
• Report of International Human Pancreas and Islet Transplantation Registry Cases Through 1981

  1982cited by this paper
• Total lymphoid irradiation in rat heart allografts: dose, fractionation, and combination with cyclosporin-A.

  1981cited by this paper
• The effects of cyclosporin A on the immune system.

  1981cited by this paper
• Cyclosporin-A in clinical organ grafting.

  1981cited by this paper
• Hormonal and metabolic effects of a pancreatic endocrine graft. Vascularized segmental transplantation in insulin-dependent diabetic patients.

  1981cited by this paper
• Properties of cyclosporin--A-induced graft acceptance.

  1981cited by this paper
• Total lymphoid irradiation: critical timing and combination with cyclosporin A for immunosuppression in a rat heart allograft model.

  1981cited by this paper
• A study of eleven drug regimens using cyclosporin-A to suppress renal allograft rejection in the dog.

  1981cited by this paper
• Cyclosporin A.

  1981cited by this paper
• Effect of cyclosporin A on human lymphocyte responses in vitro. II. Induction of specific alloantigen unresponsiveness mediated by a nylon wool adherent suppressor cell.

  1981cited by this paper
• Cyclosporin-A--present experimental status.

  1981cited by this paper
• Segmental pancreas transplantation from living related and cadaver donors: a clinical experience.

  1981cited by this paper
• The specificity of post-cyclosporin "tolerance".

  1981cited by this paper
• A TECHNIQUE FOR TRANSPLANTING PANCREATIC ISLETS AS A VASCULARIZED GRAFT AND PREVENTION OF REJECTION WITH CYCLOSPORIN A

  1981cited by this paper
• Results of a prospective randomized study on the effect of splenectomy versus no splenectomy in renal transplant patients.

  1981cited by this paper
• Differential effects of cyclosporin-A on lymphocyte subpopulations.

  1981cited by this paper
• Effect of cyclosporin A on rejection of pancreatic islets transplanted under the renal capsule.

  1981cited by this paper
• Dominant effect of transfusions on kidney graft survival.

  1980cited by this paper
• Effect of cyclosporin A on human lymphocyte responses in vitro. I. CsA allows for the expression of alloantigen-activated suppressor cells while preferentially inhibiting the induction of cytolytic effector lymphocytes in MLR.

  1980cited by this paper
• Suppression of Rejection of Allogeneic Islet Tissue in the Rat

  1980cited by this paper
• STUDIES ON THE IMMUNOSUPPRESSIVE PROPERTIES OF CYCLOSPORIN A IN RATS RECEIVING RENAL ALLOGRAFTS

  1980cited by this paper
• Detrimental effect of steroids on cyclosporin-A-induced prolonged allograft survival.

  1980cited by this paper
• Prolongation of heterotopic cardiac allografts in rats by cyclosporin A.

  1980cited by this paper
• Transplantation of Dispersed Pancreatic Islet Tissue in Humans: Autografs and Allografts

  1980cited by this paper
• The use of cyclosporin A and prednisone in cadaver kidney transplantation.

  1980cited by this paper
• Selective effects of cyclosporin A on functional B cell subsets in the mouse.

  1980cited by this paper
• Prolongation of canine pancreas allografts with cyclosporin A.

  1980cited by this paper
• Vascularized pancreas versus isolated islet allografts: an immunological comparison.

  1980cited by this paper
• The effect of cyclosporin A on experimental pancreas allografts in the rat.

  1980cited by this paper
• Cyclosporin A prolongation of segmental pancreatic and islet allograft function in rats.

  1980cited by this paper
• Studies on the mechanism of action of cyclosporin A.

  1980cited by this paper
• Human islet autotransplantation following pancreatectomy.

  1979cited by this paper
• Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers.

  1979cited by this paper
• Transplantation of the pancreas.

  1979cited by this paper
• CYCLOSPORIN A: AN IMMUNOSUPPRESSIVE AGENT PREFERENTIALLY ACTIVE AGAINST PROLIFERATING T CELLS

  1979cited by this paper
• Induction of specific tolerance in rabbits by kidney allografting and short periods of cyclosporin-A treatment.

  1979cited by this paper
• Ten Year Experience with Renal Transplantation in Juvenile Onset Diabetics

  1979cited by this paper
• Pancreatic transplantation in man: a new method of pancreas preparation and results on diabetes correction.

  1979cited by this paper
• DL‐ethionine Treatment of Adult Pancreatic Donors Amelioration of Diabetes in Multiple Recipients with Tissue From a Single Donor

  1979cited by this paper
• Cyclosporin A in patients receiving renal allografts from cadaver donors.

  1978cited by this paper
• Synergistic effect of donor-specific soluble membrane antigen injection and antithymocyte serum administration on the survival of islet allografts in rats.

  1978cited by this paper
• [Transplantation of the pancreas].

  1978cited by this paper
• THE COURSE OF PANCREAS ALLOGRAFTS IN RATS CONDITIONED BY SPLEEN ALLOGRAFTS1

  1978cited by this paper
• Transplantation tolerance in adult rats using total lymphoid irradiation: permanent survival of skin, heart, and marrow allografts

  1978cited by this paper
• Effects of the new anti-lymphocytic peptide cyclosporin A in animals.

  1977cited by this paper
• Calculations on long-term graft and patient survival in human kidney transplantation.

  1977cited by this paper
• Transplantation of the pancreas.

  1976cited by this paper
• Improved technique of heart transplantation in rats.

  1969cited by this paper

• In Vitro Studies of Squalene‐Gusperimus Nanoparticles in Islet‐Containing Alginate Microcapsules to Regulate the Immune Response in the Immediate Posttransplant Period

  2021cites this paper
• Glucose Intolerance in Myotonic Dystrophy

  2018cites this paper
• Polyclonal and monoclonal antibodies for induction therapy in kidney transplant recipients.

  2017cites this paper
• Pushing the envelope: living donor pancreas transplantation

  2012cites this paper
• A cross-sectional study for glucose intolerance of myotonic dystrophy.

  2009cites this paper
• Functional and morphological study of cultured pancreatic islets treated with cyclosporine.

  2007cites this paper
• Immunosuppression for pancreas transplantation

  2005cites this paper
• Evaluation of factors to decrease bioavailability of cyclosporin A in rats with gentamicin-induced acute renal failure.

  2004cites this paper
• Living Donor Pancreas Transplantation

  2002cites this paper
• Use of antilymphocyte induction therapy in liver transplantation: A European perspective.

  1999cites this paper
• Relationship between erythrocyte-to-plasma distribution ratio of cyclosporin and lymphocyte proliferation in renal transplant patients

  1997cites this paper
• Effect of streptozotocin-induced diabetes on cyclosporin A disposition in rats.

  1996cites this paper
• Osmotic separation of pancreatic exocrine cells from crude islet cell preparations.

  1996cites this paper
• Osmotic Separation of Pancreatic Exocrine Cells from Crude Islet Cell Preparations

  1996cites this paper
• Relationship between apparent total body clearance of cyclosporin A and its erythrocyte-to-plasma distribution ratio in renal transplant patients.

  1995cites this paper
• Inhibitory effects of cyclosporin A on rat insulinoma cell proliferation, polyamine content and insulin secretion.

  1994cites this paper
• A simple method for predicting the cyclosporin A erythrocyte-to-plasma distribution ratio in blood, and its clinical assessment.

  1994cites this paper
• Lymphatic transport of cyclosporin A from the abdominal cavity

  1994cites this paper
• Preferential rejection of the kidney in a simultaneous kidney-pancreas transplant.

  1994cites this paper
• DESCRIPTION OF THE NEPHROLOGY TRAINING PROGRAM UNIVERSITY OF ALABAMA AT BIRMINGHAM SCHOOL OF MEDICINE

  1994cites this paper
• Pharmacokinetics of cyclosporin A after intravenous administration to rats in various disease states.

  1993cites this paper
• Erythrocyte uptake and protein binding of cyclosporin A (CyA) in human blood: factors affecting CyA concentration in erythrocytes.

  1993cites this paper
• Evolution of kidney, pancreas, and islet transplantation for patients with diabetes at the University of Minnesota.

  1993cites this paper
• Effects of cyclosporin A immunosuppression on pancreaticoduodenal transplantation in alloxan-diabetic rats.

  1992cites this paper
• Transplantation of Purified Islet Cells in Diabetic Rats: III. Immunosuppressive Effect of Cyclosporin

  1991cites this paper
• A model to account for the blood-to-plasma distribution of cyclosporin A in human blood.

  1990cites this paper
• Glucose Homeostasis and Insulin Secretion During Chronic Treatment With Cyclosporin in Nondiabetic Humans

  1989cites this paper
• A comparison of canine renal and islet transplantation with cyclosporine: assessment of islet immunogenicity.

  1989cites this paper
• The influence of cyclosporin A on T cell activation, cytokine gene expression and cell-mediated immunity

  1989cites this paper
• CYCLOSPORINE'S EFFECT ON CANINE PANCREATIC ENDOCRINE FUNCTION

  1988cites this paper
• Cyclosporin-induced inhibition of insulin release. Possible role of voltage-dependent calcium transport channels.

  1988cites this paper
• Effect of cyclosporine on glucose metabolism in kidney transplant recipients.

  1988cites this paper
• Biological and pharmaceutical factors affecting the absorption and lymphatic delivery of ciclosporin A from gastrointestinal tract.

  1988cites this paper
• Cyclosporin A and islet function.

  1988cites this paper
• Daily and alternate-day cyclosporine immunosuppressive regimens and synergism with azathioprine.

  1987cites this paper
• Pancreas transplantation.

  1987cites this paper
• Pancreas transplantation at the University of Minnesota: donor and recipient selection, operative and postoperative management, and outcome.

  1987cites this paper
• New Treatment Concepts for Insulin-Dependent Diabetes Mellitus

  1987cites this paper
• Pancreas transplantation.

  1986cites this paper
• COMPARISON OF THE IMMUNOGENICITY OF PURIFIED AND UNPURIFIED MURINE ISLET ALLOGRAFTS

  1986cites this paper
• Release of serotonin from human carcinoid tumor cells In Vitro nd grown in the anterior eye chamber of the rat

  1986cites this paper
• Pancreas transplantation.

  1986cites this paper
• Early change of myocardial water during acute cardiac allograft rejection.

  1986cites this paper
• Cyclosporin-Induced Inhibition of Insulin Secretion in Isolated Rat Islets and HIT Cells

  1986cites this paper
• Limb Allotransplantation in the Rat: Extended Survival and Return of Nerve Function with Continuous Cyclosporin/Prednisone Immunosuppression

  1986cites this paper
• Circadian stage-dependent prolongation by cyclosporine of segmental pancreatic allograft function in the rat.

  1986cites this paper
• Pancreas Transplants in Diabetic Nephropathy

  1986cites this paper
• Canine pancreatic fragment allotransplantation with cyclosporine A.

  1985cites this paper
• Promotion of the selective lymphatic delivery of cyclosporin A by lipid-surfactant mixed micelles.

  1985cites this paper
• Effect of cyclosporine on host defence.

  1985cites this paper
• Total Lymphoid Irradiation for Immunosuppression

  1985cites this paper
• A New Approach to Experimental Pancreatic Islet Transplatation: Ultraviolet Irradiation

  1985cites this paper
• One institution's experience with pancreas transplantation.

  1985cites this paper
• Cyclosporin A enhances the survivability of mouse cerebral cortex grafted into the third ventricle of rat brain.

  1985cites this paper
• A Single Institution, Randomized, Prospective Trial of Cyclosporine Versus Azathioprine‐Antilymphocyte Globulin for Immunosuppression in Renal Allograft Recipients

  1985cites this paper
• Islet cell transplantation.

  1985cites this paper
• Microsurgical Models in Rats for Transplantation Research

  1985cites this paper
• Monoclonal antibody radioimmunodetection of transplant rejection.

  1985cites this paper
• Long-term effects of cyclosporin A on cultured mouse pancreatic islets

  1984cites this paper
• Immunology of Clinical and Experimental Diabetes

  1984cites this paper
• Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine.

  1984cites this paper
• Transplantation of Pancreas and Islets

  1984cites this paper
• One Hundred Pancreas Transplants at a Single Institution

  1984cites this paper
• [Indefinite survival of pancreatic allografts under cyclosporin A treatment in rats].

  1984cites this paper
• [Pancreas transplantation].

  1984cites this paper
• 膵ラ島のmicroencapsulation―Hamster・Rat間異種移殖への応用―

  1984cites this paper
• Total lymphoid irradiation.

  1983cites this paper
• Cold storage preservation of islet and pancreas grafts as assessed by in vivo function after transplantation to diabetic hosts.

  1983cites this paper
• Deterioration in glucose metabolism in pancreatic transplant recipients given cyclosporin.

  1983cites this paper
• The course of combined pancreas and spleen allografts in rats.

  1982cites this paper
• Increased Ia-antigen-bearing T cells in type I diabetes mellitus.

  1982cites this paper