What can we learn about age-related macular degeneration from other retinal diseases?

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Molecular Vision

• Publication date

  1999-11-03

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10562654
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Retinal Stimulates ATP Hydrolysis by Purified and Reconstituted ABCR, the Photoreceptor-specific ATP-binding Cassette Transporter Responsible for Stargardt Disease*

  1999cited by this paper
• A mutation in NRL is associated with autosomal dominant retinitis pigmentosa

  1999cited by this paper
• Leber congenital amaurosis caused by a homozygous mutation (R90W) in the homeodomain of the retinal transcription factor CRX: direct evidence for the involvement of CRX in the development of photoreceptor function.

  1999cited by this paper
• Retinitis pigmentosa caused by a homozygous mutation in the Stargardt disease gene ABCR

  1998cited by this paper
• Mapping of the rod photoreceptor ABC transporter (ABCR) to 1p21–p22.1 and identification of novel mutations in Stargardt’s disease

  1998cited by this paper
• Cysteine residues of photoreceptor peripherin/rds: role in subunit assembly and autosomal dominant retinitis pigmentosa.

  1998cited by this paper
• Allelic variation in ABCR associated with Stargardt disease but not age-related macular degeneration

  1998cited by this paper
• Identification of the gene responsible for Best macular dystrophy

  1998cited by this paper
• A pineal regulatory element (PIRE) mediates transactivation by the pineal/retina-specific transcription factor CRX.

  1998cited by this paper
• Autosomal recessive retinitis pigmentosa and cone-rod dystrophy caused by splice site mutations in the Stargardt's disease gene ABCR.

  1998cited by this paper
• Spectrum of ABCR gene mutations in autosomal recessive macular dystrophies

  1998cited by this paper
• De novo mutations in the CRX homeobox gene associated with Leber congenital amaurosis

  1998cited by this paper
• A range of clinical phenotypes associated with mutations in CRX, a photoreceptor transcription-factor gene.

  1998cited by this paper
• Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle

  1998cited by this paper
• The 220-kDa Rim Protein of Retinal Rod Outer Segments Is a Member of the ABC Transporter Superfamily*

  1997cited by this paper
• A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Starqardt macular dystrophy

  1997cited by this paper
• Identification of a Gene That Causes Primary Open Angle Glaucoma

  1997cited by this paper
• Mutations in RPE65 cause autosomal recessive childhood–onset severe retinal dystrophy

  1997cited by this paper
• Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor.

  1997cited by this paper
• Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration.

  1997cited by this paper
• Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.

  1997cited by this paper
• Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes.

  1997cited by this paper
• Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration.

  1997cited by this paper
• Mutations in RPE65 cause Leber's congenital amaurosis

  1997cited by this paper
• Mutation of the gene encoding cellular retinaldehyde–binding protein in autosomal recessive retinitis pigmentosa

  1997cited by this paper
• Tissue inhibitor of metalloproteinases-3 is a component of Bruch's membrane of the eye.

  1997cited by this paper
• Stargardt's ABCR is localized to the disc membrane of retinal rod outer segments

  1997cited by this paper
• Discrete expression and distribution pattern of TIMP-3 in the human retina and choroid.

  1997cited by this paper
• Subunit composition of the peripherin/rds-rom-1 disk rim complex from rod photoreceptors: hydrodynamic evidence for a tetrameric quaternary structure.

  1996cited by this paper
• A mouse model of gyrate atrophy of the choroid and retina. Early retinal pigment epithelium damage and progressive retinal degeneration.

  1996cited by this paper
• A second independent Tyr168Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy.

  1996cited by this paper
• Defective subunit assembly underlies a digenic form of retinitis pigmentosa linked to mutations in peripherin/rds and rom-1.

  1996cited by this paper
• Molecular characterization of the human gene encoding an abundant 61 kDa protein specific to the retinal pigment epithelium.

  1995cited by this paper
• A novel Ser156Cys mutation in the tissue inhibitor of metalloproteinases-3 (TIMP3) in Sorsby's fundus dystrophy with unusual clinical features.

  1995cited by this paper
• Mice lacking ornithine-delta-aminotransferase have paradoxical neonatal hypoornithinaemia and retinal degeneration.

  1995cited by this paper
• Heterologous expression of photoreceptor peripherin/rds and Rom-1 in COS-1 cells: assembly, interactions, and localization of multisubunit complexes.

  1995cited by this paper
• Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby's fundus dystrophy

  1994cited by this paper
• Rapid and efficient molecular analysis of gyrate atrophy using denaturing gradient gel electrophoresis.

  1994cited by this paper
• Digenic retinitis pigmentosa due to mutations at the unlinked peripherin/RDS and ROM1 loci.

  1994cited by this paper
• The gene for the retinal pigment epithelium-specific protein RPE65 is localized to human 1p31 and mouse 3.

  1994cited by this paper
• Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro.

  1993cited by this paper
• Ornithine delta-aminotransferase mutations in gyrate atrophy. Allelic heterogeneity and functional consequences.

  1992cited by this paper
• A conserved retina-specific gene encodes a basic motif/leucine zipper domain.

  1992cited by this paper
• Sorsby's fundus dystrophy. A light and electron microscopic study.

  1989cited by this paper
• An initiator codon mutation in ornithine-delta-aminotransferase causing gyrate atrophy of the choroid and retina.

  1988cited by this paper

• Retinal toxicities of Systemic Anticancer Drugs.

  2021cites this paper
• Title of Dissertation

  2019cites this paper
• Retinal Cell Degeneration in Animal Models

  2016cites this paper
• Animal Models in Biomedical Research

  2015cites this paper
• Retinal pigment epithelium response to oxidant injury in the pathogenesis of early age-related macular degeneration.

  2012cites this paper
• The physiological impact of microRNA gene regulation in the retina

  2012cites this paper
• Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies

  2011cites this paper
• Retinal ultrastructure of murine models of dry age-related macular degeneration (AMD).

  2010cites this paper
• Effects of long-term administration of 9-cis-retinyl acetate on visual function in mice.

  2009cites this paper
• Identification of photoreceptor genes affected by PRPF31 mutations associated with autosomal dominant retinitis pigmentosa.

  2007cites this paper
• The challenge of modeling macular degeneration in mice.

  2007cites this paper
• Critical role of AGEs/ALEs in age-related dysfunction of the retinal pigment epithelium

  2007cites this paper
• Localization of septin 8 in murine retina, and spatiotemporal expression of septin 8 in a murine model of photoreceptor cell degeneration.

  2007cites this paper
• Génétique de la dégénérescence maculaire liée à l’âge

  2007cites this paper
• A clinician's view of the molecular genetics of age-related maculopathy.

  2007cites this paper
• Indocyanine green angiography features of malattia leventinese

  2006cites this paper
• A 76-year-old man with macular degeneration.

  2006cites this paper
• A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride.

  2006cites this paper
• The role of inflammation in the pathogenesis of age-related macular degeneration.

  2006cites this paper
• Analysis of Hemicentin-1, hOgg1, and E-selectin single nucleotide polymorphisms in age-related macular degeneration.

  2005influential citation
• UvA-DARE ( Digital Academic Repository ) Spare the rod and spoil the eye

  2005cites this paper
• Aberrant accumulation of fibulin-3 in the endoplasmic reticulum leads to activation of the unfolded protein response and VEGF expression.

  2005cites this paper
• Factors affecting statistical power in the detection of genetic association.

  2005cites this paper
• Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases.

  2005cites this paper
• Genetics Diseases of the Eye in India

  2004cites this paper
• Late-onset autosomal dominant macular dystrophy with choroidal neovascularization and nonexudative maculopathy associated with mutation in the RDS gene.

  2003cites this paper
• Neural remodeling in retinal degeneration.

  2003cites this paper
• Tissue inhibitor of metalloproteinases-3 and Sorsby fundus dystrophy.

  2003cites this paper
• Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases.

  2003cites this paper
• Ophthalmic drug discovery

  2003cites this paper
• Molecular characterization of the skate peripherin/rds gene: relationship to its orthologues and paralogues.

  2003cites this paper
• Animal Model Progressive Age-Related Changes Similar to Age-Related Macular Degeneration in a Transgenic Mouse Model

  2002cites this paper
• Gene therapy for genetic and acquired retinal diseases.

  2002cites this paper
• Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model.

  2002cites this paper
• Gene expression profile of native human retinal pigment epithelium.

  2002cites this paper
• Dbest1, a drosophila homolog of human bestrophin, is not required for viability or photoreceptor integrity

  2001cites this paper
• Autosomal dominant Stargardt-like macular dystrophy.

  2001cites this paper
• Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes.

  2001cites this paper
• Ribozyme rescue of photoreceptor cells in P23H transgenic rats: long-term survival and late-stage therapy.

  2000cites this paper
• Calorie restriction modulates age-dependent changes in the retinas of Brown Norway rats.

  2000cites this paper
• A brief review of retinitis pigmentosa and the identified retinitis pigmentosa genes.

  2000influential citation