Towards an asymmetric synthesis of the bacterial peptide deformylase (PDF) inhibitor fumimycin.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Organic and biomolecular chemistry

• Publication date

  2009-11-25

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/b916372gPMID 20024097
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chemistry and biology of mycotoxins and related fungal metabolites.

  2009cited by this paper
• A short history of SHELX.

  2008cited by this paper
• Determination of absolute structure using Bayesian statistics on Bijvoet differences

  2008cited by this paper
• Recent approaches towards the asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids.

  2007cited by this paper
• Fumimycin: a peptide deformylase inhibitor with an unusual skeleton produced by Aspergillus fumisynnematus.

  2007cited by this paper
• Sulfamidation of 2-arylaldehydes and ketones with chloramine-T.

  2006cited by this paper
• Therapeutic potential of peptide deformylase inhibitors

  2005cited by this paper
• Total synthesis of LFA-1 antagonist BIRT-377 via organocatalytic asymmetric construction of a quaternary stereocenter.

  2005cited by this paper
• Bacterial Peptide deformylase inhibitors: a new class of antibacterial agents.

  2005cited by this paper
• Organocatalytic enantioselective synthesis of metabotropic glutamate receptor ligands.

  2005cited by this paper
• A novel class of inhibitors of peptide deformylase discovered through high-throughput screening and virtual ligand screening.

  2004cited by this paper
• Alpha-substituted hydroxamic acids as novel bacterial deformylase inhibitor-based antibacterial agents.

  2003cited by this paper
• Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain.

  2003cited by this paper
• Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives.

  2003cited by this paper
• Proline-catalysed asymmetric amination of alpha,alpha-disubstituted aldehydes: synthesis of configurationally stable enantioenriched alpha-aminoaldehydes.

  2003cited by this paper
• Structure-based design of a macrocyclic inhibitor for peptide deformylase.

  2003cited by this paper
• Novel approaches to antimicrobial therapy: peptide deformylase.

  2002cited by this paper
• Direct catalytic asymmetric alpha-amination of aldehydes.

  2002cited by this paper
• Direct organo-catalytic asymmetric alpha-amination of aldehydes--a simple approach to optically active alpha-amino aldehydes, alpha-amino alcohols, and alpha-amino acids.

  2002cited by this paper
• Deformylase as a novel antibacterial target.

  2001cited by this paper

• Oxone-mediated Dakin reaction of benzaldehydes to phenols

  2024cites this paper
• Total synthesis of 14-membered ring β-resorcylic acid lactone (+)-monocillin II.

  2024cites this paper
• Organocatalytic Enantioselective α-Nitrogenation of α,α-Disubstituted Aldehydes in the Absence of a Solvent

  2022cites this paper
• Molecular design of potent, hydrophilic tyrosinase inhibitors based on the natural dihydrooxyresveratrol skeleton.

  2019cites this paper
• Total synthesis of (±)-fumimycin and analogues for biological evaluation as peptide deformylase inhibitors.

  2019cites this paper
• Chemoselective room temperature E1cB N-N cleavage of oxazolidinone hydrazides from enantioselective aldehyde α-hydrazination: synthesis of (+)-1,4-dideoxyallonojirimycin.

  2016cites this paper
• Isomerization of allylbenzenes.

  2015cites this paper
• Toluene dioxygenase-catalyzed synthesis and reactions of cis-diol metabolites derived from 2- and 3-methoxyphenols.

  2015cites this paper
• Heterogeneous Dipeptide-Catalyzed α-Amination of Aldehydes in a Continuous-Flow Reactor: Effect of Residence Time on Enantioselectivity

  2015cites this paper
• Asymmetric Organocatalytic Functionalization of α,α-Disubstituted Aldehydes Through Enamine Activation

  2014cites this paper
• Alpha‐Heteroatom Functionalization of Carbonyl Compounds

  2013cites this paper
• Novel synthesis of various orthogonally protected Cα-methyllysine analogues and biological evaluation of a vapreotide analogue containing (S)-α-methyllysine.

  2013cites this paper
• International Evaluation of Research and Doctoral Training at the University of Helsinki 2005-2010: RC-Specific Evaluation of LIC - Laboratory of Inorganic Chemistry

  2012cites this paper
• Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents

  2011cites this paper
• Rapid construction of the tricyclic cores of the abietane- and icetexane-type diterpenoids

  2011cites this paper
• The total synthesis of (±)-fumimycin.

  2010cites this paper
• Synthesis of methoxyfumimycin with 1,2-addition to ketimines.

  2010cites this paper
• Enantioselective synthesis of stimulus-responsive amino acid via asymmetric α-amination of aldehyde

  2010cites this paper
• Organocatalyzed Asymmetric α-Oxidation, α-Aminoxylation and α-Amination of Carbonyl Compounds

  2010cites this paper