Acute Methotrexate-Induced Crystal Nephropathy.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  New England Journal of Medicine

• Publication date

  2015-12-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJMc1507547PMID 26716929
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A case of crystalline nephropathy.

  2015cited by this paper
• Methotrexate in the urine.

  2011cited by this paper
• Understanding and managing methotrexate nephrotoxicity.

  2006cited by this paper
• Temporary remissions in acute leukemia in children produced by folic acid antagonist, 4-aminopteroyl-glutamic acid.

  1948cited by this paper

• Prevention and Treatment of Acute Kidney Injury Associated with High-Dose Methotrexate

  2025cites this paper
• Idiopathic Granulomatous Mastitis: Immune-Pathogen Imbalance in a Treatment-Resistant Benign Inflammatory Disease

  2025cites this paper
• Predictive factors for delayed high-dose methotrexate elimination: A practical issue for diffuse large B-cell lymphoma patients.

  2025cites this paper
• Consensus on managing delayed methotrexate elimination in high-dose therapy: insights from the Middle East

  2025cites this paper
• A European consensus recommendation on the management of delayed methotrexate elimination: supportive measures, leucovorin rescue and glucarpidase treatment

  2024influential citation
• Simplified preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase

  2024cites this paper
• The Effect of Dextrose Hypotonic vs Saline Hydration on Methotrexate-Induced Nephrotoxicity in Male and Female Rats

  2024cites this paper
• Serum Methotrexate Level Predicts Acute Kidney Injury After High-Dose Methotrexate: A Case Report and Single-Center Experience

  2024cites this paper
• Clinical Risk Factors for High‐Dose Methotrexate‐Induced Oral Mucositis Following Individualized Dosing

  2024cites this paper
• Methotrexate Crystals on Electron Microscopy of Kidney Biopsy for Acute Kidney Injury

  2024cites this paper
• Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

  2024cites this paper
• Acute Kidney Injury with SARS-CoV-2 Infection in Pediatric Patients Receiving High-Dose Methotrexate Chemotherapy: A Report of Three Cases

  2023cites this paper
• Late administration of glucarpidase in methotrexate intoxication: Do we have more time than we thought?

  2023cites this paper
• Early clinical indicators of acute kidney injury caused by administering high-dose methotrexate therapy to juvenile pigs

  2023cites this paper
• External Evaluation of Population Pharmacokinetic Models for High‐Dose Methotrexate in Adult Patients with Hematological Tumors

  2023influential citation
• Acute kidney injury following methotrexate treatment

  2023cites this paper
• Acute Interstitial Nephritis and Crystalline Nephropathies

  2022cites this paper
• Acute Kidney Injury in Critically Ill Patients with Cancer.

  2022cites this paper
• Rescue Therapies for AKI in Onconephrology: Rasburicase and Glucarpidase.

  2022cites this paper
• Current Status of Therapeutic Drug Monitoring for Methotrexate, Imatinib, Paclitaxel in China.

  2022cites this paper
• Crystalline Nephropathy With High-Dose Methotrexate in a Patient With Primary CNS Lymphoma: A Case Report

  2022cites this paper
• A Systematic Review of Population Pharmacokinetic Models of Methotrexate

  2022cites this paper
• A pharmacologically-based approach to high dose methotrexate administration to investigate nephrotoxicity and acute kidney injury biomarkers in children and adolescents with newly diagnosed osteosarcoma

  2021cites this paper
• CP-25 ameliorates methotrexate induced nephrotoxicity via improving renal apoptosis and methotrexate excretion.

  2021cites this paper
• Half-dose glucarpidase as efficient rescue for toxic methotrexate levels in patients with acute kidney injury

  2021cites this paper
• Role of Salvia officinalis Silver Nanoparticles in Attenuation Renal Damage in Rabbits Exposed to Methotrexate.

  2021cites this paper
• Conventional Chemotherapy Nephrotoxicity.

  2021cites this paper
• Kidney injury and disease in patients with haematological malignancies

  2021cites this paper
• Low-dose oral methotrexate-induced crystalluria

  2020cites this paper
• The use of low doses of methotrexate during peri-cell infusion period may be a risk factor for acute kidney injury in patients subjected to hematopoietic stem cell transplantation

  2020cites this paper
• A diagnostician's field guide to crystalline nephropathies.

  2020cites this paper
• Risk factors for high‐dose methotrexate associated acute kidney injury in patients with hematological malignancies

  2020cites this paper
• High-dose methotrexate in ICU patients: a retrospective study

  2020cites this paper
• A second administration of glucarpidase in a different cycle of high-dose methotrexate: Is it safe and effective in adults?

  2020cites this paper
• Polymeric Nanoscale Drug Carriers Mediate the Delivery of Methotrexate for Developing Therapeutic Interventions Against Cancer and Rheumatoid Arthritis

  2020cites this paper
• Life-threatening complications after high-dose methotrexate and the benefits of glucarpidase as salvage therapy: a cohort study of 468 patients

  2020cites this paper
• Delayed Methotrexate Elimination after Administration of a Medium Dose of Methotrexate in a Patient with Genetic Variants Associated with Methotrexate Clearance.

  2020cites this paper
• Conventional chemotherapy

  2020cites this paper
• Effective Rescue of High Dose Methotrexate-Induced Acute Kidney Injury Using Combined Extracorporeal Modalities in a Patient with Osteosarcoma

  2020cites this paper
• ROLE OF PHARMACIST IN MANAGEMENT OF DRUG INDUCED NEPHROTOXICITY

  2020cites this paper
• i g h

  2020cites this paper
• [Methotrexate induced crystalline nephropathy: A rare histological finding on renal biopsy].

  2019cites this paper
• Lésions élémentaires des tubules rénaux

  2019cites this paper
• Methotrexate-associated toxicity in children with Down syndrome and acute lymphoblastic leukemia during consolidation therapy with high dose methotrexate according to ALL-BFM treatment regimen

  2019cites this paper
• The Iraqi Journal of Veterinary Medicine, 42(2):7-20

  2019cites this paper
• A guide to crystal‐related and nano‐ or microparticle‐related tissue responses

  2019cites this paper
• Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

  2019cites this paper
• Time course effects of methotrexate on renal handling of water and electrolytes in rats. Role of aquaporin-2 and Na-K-2Cl-cotransporter.

  2019cites this paper
• Recherche de facteurs de risque de toxicité du méthotrexate haute dose chez les patients adultes traités pour une hémopathie lymphoïde

  2019cites this paper
• Drug-induced tubulointerstitial nephritis: hypersensitivity and necroinflammatory pathways

  2019cites this paper
• Simultaneous determination of plasma methotrexate and 7‐hydroxy methotrexate by UHPLC–MS/MS in patients receiving high‐dose methotrexate therapy

  2018cites this paper
• Drug-Induced Kidney Stones and Crystalline Nephropathy: Pathophysiology, Prevention and Treatment

  2018cites this paper
• Evaluation, Identification, and Management of Acute Methotrexate Toxicity in High-dose Methotrexate Administration in Hematologic Malignancies

  2018cites this paper
• 2,4-Diamino-N10-methylpteroic acid (DAMPA) crystalluria in a patient with osteosarcoma treated with carboxypeptidase-G2 rescue after high-dose methotrexate-induced nephrotoxicity.

  2018cites this paper
• Acute kidney injury, agranulocytosis, drug-induced liver injury, and posterior reversible encephalopathy syndrome caused by high-dose methotrexate—possible role of low activity ABC and SLC drug transporters

  2018cites this paper
• Non-infectious chemotherapy-associated acute toxicities during childhood acute lymphoblastic leukemia therapy

  2017cites this paper
• Effect of single agent high-dose methotrexate-related acute kidney injury on length of hospitalization and relative dose intensity in adult patients with central nervous system lymphoma

  2017influential citation
• Clinical pharmacokinetics of methotrexate in oncology

  2017cites this paper
• Pharmacokinetics, Pharmacodynamics and Pharmacogenetics of Antileukemic Drugs

  2017cites this paper
• Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance

  2017cites this paper
• Antineoplastic Treatment and Renal Injury: An Update on Renal Pathology Due to Cytotoxic and Targeted Therapies

  2016cites this paper
• Simpli fi ed preanalytical laboratory procedures for therapeutic drug monitoring (TDM) in patients treated with high-dose methotrexate (HD-MTX) and glucarpidase

  year unknowncites this paper
• World Journal of Nephrology

  year unknowncites this paper
• A Life-Threatening Methotrexate Intoxication Associated with End-Stage Renal Disease Resolved by Late Administration of Glucarpidase: Case Report

  year unknowninfluential citation