Fibroblast‐specific adipocyte enhancer binding protein 1 is a potential pathological trigger and prognostic marker for liver fibrosis independent of etiology

Wen Zhang,Yujia Li,Ning Zhang,Shuyan Chen,X. Tong,Bingqiong Wang,Tao Huang,Hong You,Wei Chen

Published 2023 in Journal of Digestive Diseases

ABSTRACT

Aortic carboxypeptidase‐like protein (ACLP) is an extracellular protein involved in adipogenesis, epithelial‐mesenchymal transition, epithelial cell hyperplasia, and collagen fibrogenesis. This study mainly aimed to analyze the potential role of adipocyte enhancer binding protein 1 (AEBP1), the ACLP‐encoding gene, as a pathological target or prognostic marker for liver fibrosis regardless of etiology.

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