Vitamin C intake and colorectal cancer survival according to KRAS and BRAF mutation: a prospective study in two US cohorts

No abstract is available for this paper.

• Publication year

  2023

• Venue

  British Journal of Cancer

• Publication date

  2023-09-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/s41416-023-02452-2PMID 37775523PMCID PMC10667518
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Randomized, Open-Label, Multicenter, Phase 3 Study of High-Dose Vitamin C Plus FOLFOX ± Bevacizumab versus FOLFOX ± Bevacizumab in Unresectable Untreated Metastatic Colorectal Cancer (VITALITY Study)

  2022cited by this paper
• Are exposure-disease relationships assessed in cohorts of health professionals generalizable?: a comparative analysis based on WCRF/AICR systematic literature reviews

  2022cited by this paper
• Vitamin C activates pyruvate dehydrogenase (PDH) targeting the mitochondrial tricarboxylic acid (TCA) cycle in hypoxic KRAS mutant colon cancer

  2021cited by this paper
• KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases

  2021cited by this paper
• The role of vitamin C in epigenetic cancer therapy.

  2021cited by this paper
• Dietary and Supplemental Vitamin C Intake and Risk of Breast Cancer: Results from the Nurses' Health Studies.

  2021cited by this paper
• OUP accepted manuscript

  2021cited by this paper
• High-Dose Vitamin C Exerts Its Anti-cancer Effects in a Xenograft Model of Colon Cancer by Suppressing Angiogenesis.

  2021cited by this paper
• Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study

  2020cited by this paper
• Association Between Healthy Eating Patterns and Risk of Cardiovascular Disease.

  2020cited by this paper
• High-Dose Vitamin C Tends to Kill Colorectal Cancer with High MALAT1 Expression

  2020cited by this paper
• High-dose vitamin C enhances cancer immunotherapy

  2020cited by this paper
• Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers

  2020cited by this paper
• On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence

  2020cited by this paper
• Vitamin C deficiency in Australian hospitalised patients: an observational study

  2019cited by this paper
• Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies

  2018cited by this paper
• Fiber Intake and Survival After Colorectal Cancer Diagnosis

  2018cited by this paper
• Dietary Vitamin C in Human Health.

  2018cited by this paper
• Utility of inverse probability weighting in molecular pathological epidemiology

  2018cited by this paper
• Targeting the RAS-dependent chemoresistance: The Warburg connection.

  2018cited by this paper
• Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells

  2017cited by this paper
• Validity of a Dietary Questionnaire Assessed by Comparison With Multiple Weighed Dietary Records or 24-Hour Recalls

  2017cited by this paper
• The Eighth Edition AJCC Cancer Staging Manual: Continuing to build a bridge from a population‐based to a more “personalized” approach to cancer staging

  2017cited by this paper
• Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer

  2016cited by this paper
• Marine ω-3 polyunsaturated fatty acid intake and survival after colorectal cancer diagnosis

  2016cited by this paper
• Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer *

  2016cited by this paper
• Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH

  2015cited by this paper
• High-Dose Intravenous Vitamin C Combined with Cytotoxic Chemotherapy in Patients with Advanced Cancer: A Phase I-II Clinical Trial

  2015cited by this paper
• Analyses of clinicopathological, molecular, and prognostic associations of KRAS codon 61 and codon 146 mutations in colorectal cancer: cohort study and literature review

  2014cited by this paper
• Ascorbate as a Co-Factor for Fe- and 2-Oxoglutarate Dependent Dioxygenases: Physiological Activity in Tumor Growth and Progression

  2014cited by this paper
• The SLC2 (GLUT) family of membrane transporters.

  2013cited by this paper
• Bias due to left truncation and left censoring in longitudinal studies of developmental and disease processes.

  2011cited by this paper
• Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer.

  2008cited by this paper
• K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

  2008cited by this paper
• Targeting the mitogen-activated protein kinase cascade to treat cancer

  2004cited by this paper
• Levels of Plasma Vitamin E, Vitamin C, TBARS, and Cholesterol in Male Patients with Colorectal Tumors

  2003cited by this paper
• Vitamin C function and status in chronic disease.

  2002cited by this paper
• A new recommended dietary allowance of vitamin C for healthy young women

  2001cited by this paper
• Dietary reference intakes for the antioxidant nutrients: vitamin C, vitamin E, selenium, and carotenoids.

  2000cited by this paper
• Reproducibility and Validity of Food-Frequency Questionnaires

  1998cited by this paper
• The Nurses' Health Study: 20-Year Contribution to the Understanding of Health Among Women

  1997cited by this paper
• Test of the National Death Index and Equifax Nationwide Death Search.

  1994cited by this paper
• Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire.

  1993cited by this paper
• Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals.

  1992cited by this paper
• Prospective study of alcohol consumption and risk of coronary disease in men.

  1991cited by this paper
• Flexible regression models with cubic splines.

  1989cited by this paper
• Total energy intake: implications for epidemiologic analyses.

  1986cited by this paper
• Test of the National Death Index.

  1984cited by this paper
• Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/sim.2174 Adjusted Kaplan–Meier estimator and log-rank test with inverse probability of treatment weighting for survival data

  year unknowncited by this paper

• Vitamin C in the Treatment of Colorectal Cancer: Between Hope and Despair.

  2026cites this paper
• Comprehensive metabolomic and epigenomic characterization of microsatellite stable BRAF-mutated colorectal cancer

  2025cites this paper
• High-dose vitamin C: A promising anti-tumor agent, insight from mechanisms, clinical research, and challenges

  2025cites this paper
• Glucose Metabolic Reprogramming in Colorectal Cancer: From Mechanisms to Targeted Therapy Approaches

  2025cites this paper
• TET methylcytosine dioxygenases in cancer: Orchestrators of pathogenesis, immunity, immunotherapy, and chemoresistance.

  2025cites this paper
• Ascorbic Acid Analog 6-Deoxy-6-18F-Fluoro-l-Ascorbic Acid PET Imaging of 23 Various Cancer Types.

  2025cites this paper
• Association of pre- and post-diagnosis dietary total antioxidant capacity (TAC) and composite dietary antioxidant index (CDAI) with overall survival in patients with ovarian cancer: a prospective cohort study

  2025cites this paper
• Comparison of Serum Vitamins C, D, and E in Iraqi Colorectal Cancer Patients with and without Non-Alcoholic Fatty Liver Disease to Healthy Individuals

  2024cites this paper
• High-dose vitamin C as a metabolic treatment of cancer: a new dimension in the era of adjuvant and intensive therapy

  2024cites this paper
• Association Between Vitamin Intake and Colorectal Cancer: Evidence from NHANES Data

  2024cites this paper
• The Role of Dietary Vitamins and Antioxidants in Preventing Colorectal Cancer: A Systematic Review

  2024cites this paper