Comparative Analysis of the Escherichia coli Ketopantoate Hydroxymethyltransferase Crystal Structure Confirms that It Is a Member of the (βα)8 Phosphoenolpyruvate/Pyruvate Superfamily

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Journal of Bacteriology

• Publication date

  2003-07-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1128/JB.185.14.4163-4171.2003PMID 12837791PMCID PMC164873
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biosynthesis of riboflavin, folic acid, thiamine, and pantothenic acid.

  2006cited by this paper
• Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites.

  2003cited by this paper
• INSIGHT INTO CHIRAL DISCRIMINATION, MECHANISM, AND SPECIFICITY OF CLASS II ALDOLASES*

  2002cited by this paper
• Pyruvate site of pyruvate phosphate dikinase: crystal structure of the enzyme-phosphonopyruvate complex, and mutant analysis.

  2002cited by this paper
• Structure of Tagatose-1,6-bisphosphate Aldolase

  2002cited by this paper
• The structure of L-ribulose-5-phosphate 4-epimerase: an aldolase-like platform for epimerization.

  2001cited by this paper
• FUGUE: sequence-structure homology recognition using environment-specific substitution tables and structure-dependent gap penalties.

  2001cited by this paper
• The structure and domain organization of Escherichia coli isocitrate lyase.

  2001cited by this paper
• The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli.

  2001cited by this paper
• Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis

  2000cited by this paper
• Crystal structures of the metal‐dependent 2‐dehydro‐3‐deoxy‐galactarate aldolase suggest a novel reaction mechanism

  2000cited by this paper
• Enhanced genome annotation using structural profiles in the program 3D-PSSM.

  2000cited by this paper
• The crystal structure and active site location of isocitrate lyase from the fungus Aspergillus nidulans.

  2000cited by this paper
• Three-dimensional structure of phosphoenolpyruvate carboxylase: a proposed mechanism for allosteric inhibition.

  1999cited by this paper
• Helix swapping between two α/β barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg2+–oxalate

  1999cited by this paper
• Conserved residues in the mechanism of the E. coli Class II FBP-aldolase.

  1999cited by this paper
• The crystal structure of Escherichia coli class II fructose-1, 6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity.

  1999cited by this paper
• Helix swapping between two alpha/beta barrels: crystal structure of phosphoenolpyruvate mutase with bound Mg(2+)-oxalate.

  1999cited by this paper
• Plausible phosphoenolpyruvate binding site revealed by 2.6 Å structure of Mn2+‐bound phosphoenolpyruvate carboxylase from Escherichia coli

  1999cited by this paper
• JOY: protein sequence-structure representation and analysis

  1998cited by this paper
• Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel.

  1998cited by this paper
• Raster3D: photorealistic molecular graphics.

  1997cited by this paper
• Catalytic mechanism of the metal-dependent fuculose aldolase from Escherichia coli as derived from the structure.

  1996cited by this paper
• Swiveling-domain mechanism for enzymatic phosphotransfer between remote reaction sites.

  1996cited by this paper
• Phosphoenolpyruvate mutase catalysis of phosphoryl transfer in phosphoenolpyruvate: kinetics and mechanism of phosphorus-carbon bond formation.

  1996cited by this paper
• SCOP: a structural classification of proteins database for the investigation of sequences and structures.

  1995cited by this paper
• Crystal structure of Escherichia coli pyruvate kinase type I: molecular basis of the allosteric transition.

  1995influential reference
• A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A

  1995cited by this paper
• Protein structure comparison by alignment of distance matrices.

  1993cited by this paper
• A program to produce both detailed and schematic plots of protein structures

  1991cited by this paper
• From comparisons of protein sequences and structures to protein modelling and design.

  1990cited by this paper
• Knowledge based modelling of homologous proteins, Part I: Three-dimensional frameworks derived from the simultaneous superposition of multiple structures.

  1987cited by this paper
• [45] Phosphoenolpyruvate carboxylase from Escherichia coli

  1969cited by this paper

• Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages

  2025cites this paper
• Module engineering coupled with omics strategies for enhancing D-pantothenate production in Escherichia coli.

  2022cites this paper
• Structure function insights into elusive Mycobacterium tuberculosis protein Rv1916.

  2019cites this paper
• Identification and characterization of an archaeal ketopantoate reductase and its involvement in regulation of coenzyme A biosynthesis

  2013cites this paper
• Comparison of two metal-dependent pyruvate aldolases related by convergent evolution: substrate specificity, kinetic mechanism, and substrate channeling.

  2010cites this paper
• Characterization of an aldolase-dehydrogenase complex that exhibits substrate channeling in the polychlorinated biphenyls degradation pathway.

  2009cites this paper
• Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution.

  2005cites this paper
• Purification and biochemical characterization of a pyruvate-specific class II aldolase, HpaI.

  2005cites this paper
• Biosynthesis of pantothenate.

  2004cites this paper