Toxicological effects of paracetamol on the clam Ruditapes philippinarum: exposure vs recovery.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Aquatic Toxicology

• Publication date

  2017-11-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/j.aquatox.2017.09.015PMID 28982071
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Toxic effects of the antihistamine cetirizine in mussel Mytilus galloprovincialis.

  2017cited by this paper
• The influence of salinity on the toxicity of selected sulfonamides and trimethoprim towards the green algae Chlorella vulgaris.

  2016cited by this paper
• General stress, detoxification pathways, neurotoxicity and genotoxicity evaluated in Ruditapes philippinarum exposed to human pharmaceuticals.

  2016influential reference
• Occurrence of pharmaceuticals and cocaine in a Brazilian coastal zone.

  2016cited by this paper
• Caffeine impacts in the clam Ruditapes philippinarum: Alterations on energy reserves, metabolic activity and oxidative stress biomarkers.

  2016cited by this paper
• Native and introduced clams biochemical responses to salinity and pH changes.

  2016cited by this paper
• Occurrence of pharmaceutical compounds and pesticides in aquatic systems.

  2015influential reference
• Evaluation of ecotoxicological effects of drugs on Daphnia magna using different enzymatic biomarkers.

  2015cited by this paper
• Chronic toxicity of the antiepileptic carbamazepine on the clam Ruditapes philippinarum.

  2015influential reference
• Seasonal distribution of pharmaceuticals in marine water and sediment from a Mediterranean coastal lagoon (SE Spain).

  2015cited by this paper
• Fate of pharmaceuticals in full-scale source separated sanitation system.

  2015cited by this paper
• Biochemical effects of the pharmaceutical drug paracetamol on Anguilla anguilla

  2015influential reference
• Occurrence of pharmaceuticals, hormones, and perfluorinated compounds in groundwater in Taiwan

  2015influential reference
• A 3-year study on occurrence of emerging contaminants in an urban stream of São Paulo State of Southeast Brazil

  2015influential reference
• Inhibitory effects of pain relief drugs on neurological enzymes: implications on their potential neurotoxicity to aquatic animals.

  2015cited by this paper
• Oxidative pathways of chemical toxicity and oxidative stress biomarkers in marine organisms.

  2014influential reference
• Effect of acetaminophen exposure in Oncorhynchus mykiss gills and liver: detoxification mechanisms, oxidative defence system and peroxidative damage.

  2014influential reference
• Physiological and biochemical responses of the Polychaete Diopatra neapolitana to organic matter enrichment.

  2014influential reference
• The impact of paracetamol on selected biomarkers of the mollusc species Corbicula fluminea

  2014cited by this paper
• Presence of the pharmaceutical drug carbamazepine in coastal systems: effects on bivalves.

  2014influential reference
• Biochemical and standard toxic effects of acetaminophen on the macrophyte species Lemna minor and Lemna gibba

  2014influential reference
• Toxic potential of paracetamol to freshwater organisms: a headache to environmental regulators?

  2014influential reference
• Biochemical effects of acetaminophen in aquatic species: edible clams Venerupis decussata and Venerupis philippinarum

  2013influential reference
• Removal of emerging contaminants in sewage water subjected to advanced oxidation with ozone.

  2013influential reference
• Development of a simple analytical method for the simultaneous determination of paracetamol, paracetamol-glucuronide and p-aminophenol in river water.

  2013influential reference
• Application of a Biomarker Response Index for Ranking the Toxicity of Five Pharmaceutical and Personal Care Products (PPCPs) to the Bivalve Dreissena polymorpha

  2013cited by this paper
• Identification of biomarkers responsive to chronic exposure to pharmaceuticals in target tissues of Carcinus maenas.

  2013influential reference
• Fármacos em Uma Estação de Tratamento de Esgoto na Região Centro-Oeste do Brasil e os Riscos aos Recursos Hídricos

  2012cited by this paper
• Effect of chronic exposure to acetaminophen and lincomycin on Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa, and potential mechanisms of endocrine disruption.

  2012influential reference
• Fast and comprehensive multi-residue analysis of a broad range of human and veterinary pharmaceuticals and some of their metabolites in surface and treated waters by ultra-high-performance liquid chromatography coupled to quadrupole-linear ion trap tandem mass spectrometry.

  2012influential reference
• Microsomal oxidative damage promoted by acetaminophen metabolism.

  2011cited by this paper
• Guanidino compounds inhibit acetylcholinesterase and butyrylcholinesterase activities: Effect neuroprotector of vitamins E plus C

  2010cited by this paper
• Effects on feeding rate and biomarker responses of marine mussels experimentally exposed to propranolol and acetaminophen

  2010influential reference
• Occurrence and fate of human pharmaceuticals in the environment.

  2010cited by this paper
• Determination of multiple pharmaceutical classes in surface and ground waters by liquid chromatography-ion trap-tandem mass spectrometry.

  2009influential reference
• PERMANOVA+ for PRIMER. Guide to software and statistical methods

  2008cited by this paper
• Analysis of ecologically relevant pharmaceuticals in wastewater and surface water using selective solid-phase extraction and UPLC-MS/MS.

  2008influential reference
• Seasonal variations of several pharmaceutical residues in surface water and sewage treatment plants of Han River, Korea.

  2008influential reference
• Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea.

  2007cited by this paper
• Pilot survey monitoring pharmaceuticals and related compounds in a sewage treatment plant located on the Mediterranean coast.

  2007influential reference
• Ocorrência de Interferentes Endócrinos e Produtos Farmacêuticos em Águas Superficiais da Região de Campinas (SP, Brasil)

  2007influential reference
• Oxidative stress in Perna perna and other bivalves as indicators of environmental stress in the Brazilian marine environment: antioxidants, lipid peroxidation and DNA damage.

  2007cited by this paper
• New insights into the mechanism of action of acetaminophen: Its clinical pharmacologic characteristics reflect its inhibition of the two prostaglandin H2 synthases

  2006cited by this paper
• Predicted and measured concentrations for selected pharmaceuticals in UK rivers: implications for risk assessment.

  2006influential reference
• Development of a multi-residue analytical methodology based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) for screening and trace level determination of pharmaceuticals in surface and wastewaters.

  2006influential reference
• Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method

  2006cited by this paper
• Ecotoxicology of human pharmaceuticals.

  2006cited by this paper
• Consequences of treated water recycling as regards pharmaceuticals and drugs in surface and ground waters of a medium-sized Mediterranean catchment.

  2006influential reference
• Cellular energy allocation in zebra mussels exposed along a pollution gradient: linking cellular effects to higher levels of biological organization.

  2004cited by this paper
• Effects of chlorpyrifos on the endogenous rhythm of the Manila clam, Ruditapes philippinarum (Bivalvia: Veneridae).

  2004cited by this paper
• Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.

  2002influential reference
• Casarett and Doull's toxicology : the basic science of poisons

  2001cited by this paper
• Hypoxia, hyperoxia and exposure to potassium dichromate or fenitrothion alter the energy metabolism in Chironomus riparius Mg. (Diptera: Chironomidae) larvae.

  2001cited by this paper
• Human pharmaceuticals in the aquatic environment a review.

  2001cited by this paper
• Effects of salinity on endogenous rhythm of the Manila clam, Ruditapes philippinarum (Bivalvia: Veneridae)

  2001cited by this paper
• Pharmaceuticals and personal care products in the environment: agents of subtle change?

  1999cited by this paper
• The use of biomarkers in Daphnia magna toxicity testing. IV. Cellular Energy Allocation: a new methodology to assess the energy budget of toxicant-stressed Daphnia populations

  1997cited by this paper
• Series: current issues in mutagenesis and carcinogenesis, No. 65. The genotoxicity and carcinogenicity of paracetamol: a regulatory (re)view.

  1996cited by this paper
• Oxidative stress transforms acetylcholinesterase to a molten-globule-like state.

  1994cited by this paper
• A textbook of modern toxicology

  1987influential reference
• Assays of glutathione peroxidase.

  1984cited by this paper
• Mechanism of action of N-acetylcysteine in the protection against the hepatotoxicity of acetaminophen in rats in vivo.

  1983cited by this paper
• Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

  1979influential reference
• Microsomal lipid peroxidation.

  1978cited by this paper
• Respiration and the activity of the respiratory electron transport system in marine zooplankton1

  1975cited by this paper
• Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.

  1974influential reference
• Superoxide dismutase: improved assays and an assay applicable to acrylamide gels.

  1971cited by this paper
• A new and rapid colorimetric determination of acetylcholinesterase activity.

  1961influential reference
• COLORIMETRIC METHOD FOR DETER-MINATION OF SUGAR AND RELATED SUBSTANCE

  1956influential reference
• THE BIURET REACTION IN THE DETERMINATION OF SERUM PROTEINS I. A STUDY OF THE CONDITIONS NECESSARY FOR THE PRODUCTION OF A STABLE COLOR WHICH BEARS A QUANTITATIVE RELATIONSHIP TO THE PROTEIN CONCENTRATION

  1940cited by this paper

• Acclimation and recovery dynamics of behavioral and coloration responses of a common fish (Squalius cephalus) to paracetamol exposure.

  2025cites this paper
• Cellular Responses of Ruditapes philippinarum Clams to Global Changes: Assessing the Risks of Rising Temperatures and E-Waste

  2025cites this paper
• Biochemical and molecular stress responses to enrofloxacin in Mytilus galloprovincialis: transient or lasting effects?

  2025cites this paper
• Paracetamol environmental remediation and ecotoxicology: a review

  2024cites this paper
• A multi-approach analysis of the toxicity of a commercial formulation of monensin on Rhinella arenarum embryos and larvae.

  2024cites this paper
• Assessing the ecological impact of pesticides/herbicides on algal communities: A comprehensive review.

  2024cites this paper
• Combined effects of fluoroquinolone antibiotic enrofloxacin and rising sea temperatures on the health of the Mediterranean mussel (Mytilus galloprovincialis): exploring physiological, biochemical, and energetic balance dynamics.

  2024cites this paper
• Microalgae as potential agents for biochar production: Future of industrial wastewater treatment

  2024cites this paper
• Recoverability of zebrafish from decabromodiphenyl ether exposure: The persisted interference with extracellular matrix production and collagen synthesis and the enhancement of arrhythmias.

  2024cites this paper
• Toxic effects of a mixture of pharmaceuticals in Mytilus galloprovincialis: The case of 17α-ethinyl estradiol and salicylic acid.

  2023cites this paper
• Sublethal effects of acetaminophen exposure on benthic aquatic animal (Hydra magnipapillata)

  2023influential citation
• Can temperature influence the impacts induced in Mytilus galloprovincialis by neodymium? Comparison between exposure and recovery periods.

  2022cites this paper
• NON-CONVENTIONAL PROCESSES APPLIED FOR THE REMOVAL OF PHARMACEUTICS COMPOUNDS IN WATERS: A REVIEW

  2022cites this paper
• How will different scenarios of rising seawater temperature alter the response of marine species to lithium?

  2022cites this paper
• Time- and dose-dependent biological effects of a sub-chronic exposure to realistic doses of salicylic acid in the gills of mussel Mytilus galloprovincialis

  2022cites this paper
• Biochemical alterations caused by lanthanum and gadolinium in Mytilus galloprovincialis after exposure and recovery periods.

  2022cites this paper
• Insights into the sulfite activation by cobalt(II) sulfide for acetaminophen removal: A synergistic catalysis and DFT calculations

  2022cites this paper
• Assessment of Paracetamol Toxic Effects under Varying Seawater pH Conditions on the Marine Polychaete Hediste diversicolor Using Biochemical Endpoints

  2022influential citation
• Understanding the bioaccumulation of pharmaceutical active compounds by clams Ruditapes decussatus exposed to a UWWTP discharge.

  2022cites this paper
• Low concentrations of ciprofloxacin alone and in combination with paracetamol induce oxidative stress, upregulation of apoptotic-related genes, histological alterations in the liver, and genotoxicity in Danio rerio.

  2022cites this paper
• Microbiota dysbiosis influences immune system and muscle pathophysiology of dystrophin‐deficient mice

  2022cites this paper
• Long-term exposure of marine mussels to paracetamol: is time a healer or a killer?

  2021cites this paper
• The behavioral and antioxidant response of the bivalve Gomphina veneriformis to sediment burial effect

  2021cites this paper
• Survival and malformations rates, oxidative status in early life stages of Cyprinus carpio due to exposure to environmentally realistic concentrations of paracetamol.

  2021cites this paper
• Behavioral, physiological and biochemical responses and differential gene expression in Mytilus galloprovincialis exposed to 17 alpha-ethinylestradiol and sodium lauryl sulfate.

  2021cites this paper
• Effective biomarkers to assess the toxicity of pharmaceutical residues on marine bivalves

  2021cites this paper
• Effects of paracetamol on the polychaete Hediste diversicolor: occurrence of oxidative stress, cyclooxygenase inhibition and behavioural alterations

  2021cites this paper
• Dangerous connections: biochemical and behavioral traits in Daphnia magna and Daphnia longispina exposed to ecologically relevant amounts of paracetamol

  2021cites this paper
• Nanoadsorbents in focus for the remediation of environmentally-related contaminants with rising toxicity concerns.

  2021cites this paper
• Influence of surface hydrophobicity/hydrophilicity of biochar on the removal of emerging contaminants

  2020cites this paper
• Combined effects of salinity changes and salicylic acid exposure in Mytilus galloprovincialis.

  2020cites this paper
• Innovative spherical biochar for pharmaceutical removal from water: Insight into adsorption mechanism.

  2020cites this paper
• Antioxidative and neurotoxicity effects of acute and chronic exposure of the estuarine polychaete Hediste diversicolor to paracetamol.

  2020cites this paper
• Anti-inflammatory drugs in the marine environment: Bioconcentration, metabolism and sub-lethal effects in marine bivalves.

  2020cites this paper
• Reynoutria japonica, an invasive herb as a source of activated carbon for the removal of xenobiotics from water.

  2020cites this paper
• Biochemical and physiological responses of two clam species to Triclosan combined with climate change scenario.

  2020cites this paper
• Biological uptake, depuration and biochemical effects of diclofenac and carbamazepine in Carassius carassius.

  2020cites this paper
• Biomarker Responses of the Clam Ruditapes decussatus Exposed to a Complex Mixture of Environmental Stressors under the Influence of an Urban Wastewater‐Treatment Plant

  2020cites this paper
• Introduction and Historical Findings That Focused Nonsteroidal Anti-Inflammatory Drugs as Emerging Pollutant

  2020cites this paper
• The Antioxidant defense Responses of Sea cucumber Holothuria polii Against Rickettsia-like organism (RLOs) Infection and Heavy Metal Pollution in Alexandria coast

  2020cites this paper
• The influence of climate change related factors on the response of two clam species to diclofenac.

  2019cites this paper
• Pharmaceuticals in freshwater aquatic environments: A comparison of the African and European challenge.

  2019cites this paper
• Nanostructured Materials for Treating Aquatic Pollution

  2019influential citation
• Evidences of metabolic alterations and cellular damage in mussels after short pulses of Ti contamination.

  2019cites this paper
• Effects of common pharmaceutical drugs (paracetamol and acetylsalicylic acid) short term exposure on biomarkers of the mussel Mytilus spp.

  2019cites this paper
• Recovery period of Folsomia candida influence the impact of nonylphenol and phenanthrene on the tolerance of drought and heat shock.

  2019cites this paper
• Biochemical and physiological responses induced in Mytilus galloprovincialis after a chronic exposure to salicylic acid.

  2019cites this paper
• Ecotoxicological responses of Chironomus riparius to Eucalyptus and Alnus leaf leachates: from biochemical to life-history effects

  2019cites this paper
• Integrated biomarker response index to assess toxic effects of environmentally relevant concentrations of paracetamol in a neotropical catfish (Rhamdia quelen).

  2019cites this paper
• Effects of commonly used therapeutic drugs, paracetamol, and acetylsalicylic acid, on key physiological traits of the sea snail Gibbula umbilicalis

  2019cites this paper
• Removal of Diclofenac, Paracetamol and Metronidazole using a carbon-polymeric membrane

  2019cites this paper
• Toxic Effects of Metal Nanoparticles in Marine Invertebrates

  2019cites this paper
• Effects of acetaminophen in oxidative stress and neurotoxicity biomarkers of the gastropod Phorcus lineatus

  2019cites this paper
• Evaluation of pharmaceutical toxic effects of non-standard endpoints on the macrophyte species Lemna minor and Lemna gibba.

  2019cites this paper
• Phytoremediation: green technology for the removal of mixed contaminants of a water supply reservoir

  2019cites this paper
• Assessment of biochemical alterations in the neotropical fish species Phalloceros harpagos after acute and chronic exposure to the drugs paracetamol and propranolol

  2018cites this paper
• Influence of temperature rise on the recovery capacity of Mytilus galloprovincialis exposed to mercury pollution

  2018cites this paper
• Acute and chronic effects of paracetamol exposure on Daphnia magna: how oxidative effects may modulate responses at distinct levels of organization in a model species

  2018cites this paper
• Gene expression and genotoxicity in Manila clam (Ruditapes philippinarum) modulated by sediment contamination and lagoon dynamics in the Po river delta.

  2018cites this paper
• Emerging Pollutants–Part I: Occurrence, Fate and Transport

  2018cites this paper
• Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review.

  2018cites this paper
• Novel approach for evaluating pharmaceuticals toxicity using Daphnia model: analysis of the mode of cytochrome P450-generated metabolite action after acetaminophen exposure.

  2018cites this paper
• Long-term exposure of Mytilus galloprovincialis to diclofenac, Ibuprofen and Ketoprofen: Insights into bioavailability, biomarkers and transcriptomic changes.

  2018cites this paper