Direct Modulation of the Guard Cell Outward-Rectifying Potassium Channel (GORK) by Abscisic Acid.

Abscisic acid (ABA) induces turgor loss and hence stomatal closure by promoting rapid net K+ efflux from guard cells (GCs) through outward-rectifying K+ (K+out) channels (Schroeder et al., 1987; Blatt, 1990). The mechanisms of ABA signaling in GCs are detailed elsewhere (see Munemasa et al., 2015; Weiner et al., 2010; Pandey et al., 2007). Briefly, ABA binds to the PYR/PYL/RCARs, a family of soluble steroidogenic acute regulatory-related lipid transfer (START) proteins, and, in turn, inactivates the downstream PP2C (type 2C protein phosphatase), leading to the activation of SnRK2.6 (SNF1 [sucrose non-fermenting-1-related protein kinase]/OST1 [open stomata 1]) protein kinases.

• Publication year

  2017

• Venue

  Molecular Plant

• Publication date

  2017-11-06

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.molp.2017.08.010PMID 28844521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Early Responses to Severe Drought Stress in the Arabidopsis thaliana Cell Suspension Culture Proteome

  2018cited by this paper
• Discovery of Novel Functional Centers With Rationally Designed Amino Acid Motifs

  2018cited by this paper
• The Arabidopsis AtPP2CA Protein Phosphatase Inhibits the GORK K+ Efflux Channel and Exerts a Dominant Suppressive Effect on Phosphomimetic-activating Mutations*

  2016cited by this paper
• Mechanisms of abscisic acid-mediated control of stomatal aperture.

  2015cited by this paper
• Clustering of the K+ channel GORK of Arabidopsis parallels its gating by extracellular K+

  2014cited by this paper
• Structural and functional insights into core ABA signaling.

  2010cited by this paper
• A Gate-Latch-Lock Mechanism for Hormone Signaling by Abscisic Acid Receptors

  2009cited by this paper
• Two novel GPCR-type G proteins are abscisic acid receptors in Arabidopsis.

  2009cited by this paper
• Roles of ion channels and transporters in guard cell signal transduction

  2007cited by this paper
• The Arabidopsis outward K+ channel GORK is involved in regulation of stomatal movements and plant transpiration

  2003cited by this paper
• GORK, a delayed outward rectifier expressed in guard cells of Arabidopsis thaliana, is a K+‐selective, K+‐sensing ion channel

  2000cited by this paper
• Induction of RAB18 gene expression and activation of K+ outward rectifying channels depend on an extracellular perception of ABA in Arabidopsis thaliana suspension cells.

  1999cited by this paper
• Membrane transport in stomatal guard cells: The importance of voltage control

  1992cited by this paper
• Potassium channel currents in intact stomatal guard cells: rapid enhancement by abscisic acid

  1990cited by this paper
• Voltage dependence of K channels in guard-cell protoplasts.

  1987cited by this paper

• A New Paradigm for the Stomatal Closures: ABA-Dependent Stomatal Closures and ABA-Independent Stomatal Closures

  2026cites this paper
• Function of key ion channels in abiotic stresses and stomatal dynamics.

  2025cites this paper
• Functions and Synthesis of Abscisic Acid (ABA) in Humans—Insights from Computational Approaches

  2025influential citation
• Morphological, Anatomical, and Physiological Characteristics of Heteroblastic Acacia melanoxylon Grown under Weak Light

  2024cites this paper
• Myosin-binding protein 13 mediates primary seed dormancy via abscisic acid biosynthesis and signaling in Arabidopsis.

  2024cites this paper
• Moonlighting Crypto-Enzymes and Domains as Ancient and Versatile Signaling Devices

  2024influential citation
• Genome-wide association mapping and transcriptomic analysis reveal key drought-responding genes in barley seedlings

  2023cites this paper
• Endogenous ion channels expressed in human embryonic kidney (HEK-293) cells

  2022cites this paper
• Abscisic acid (ABA) signaling: finding novel components off the beaten track

  2022cites this paper
• Melatonin as a regulator of plant ionic homeostasis: implications for abiotic stress tolerance.

  2022cites this paper
• Amino acid motifs for the identification of novel protein interactants

  2022cites this paper
• A distinct giant coat protein complex II vesicle population in Arabidopsis thaliana

  2021cites this paper
• A tandem motif-based and structural approach can identify hidden functional phosphodiesterases

  2021cites this paper
• Computational Identification of Functional Centers in Complex Proteins: A Step-by-Step Guide With Examples

  2021influential citation
• Moonlighting adenylyl cyclases in plants – an Arabidopsis thaliana 9-cis-epoxycarotenoid dioxygenase as point in case

  2021cites this paper
• Functional Crypto-Adenylate Cyclases Operate in Complex Plant Proteins

  2021cites this paper
• Identification and expression analysis of Shaker K+ channel genes in millet (Setaria italica) under abiotic stresses

  2021influential citation
• Gene Frequency Shift in Relict Abies pinsapo Forests Associated with Drought-Induced Mortality: Preliminary Evidence of Local-Scale Divergent Selection

  2021cites this paper
• Structural and Functional Insights into the Role of Guard Cell Ion Channels in Abiotic Stress-Induced Stomatal Closure

  2021cites this paper
• Bacillus subtilis and Pseudomonas fluorescens Trigger Common and Distinct Systemic Immune Responses in Arabidopsis thaliana Depending on the Pathogen Lifestyle

  2020cites this paper
• A natriuretic peptide from Arabidopsis thaliana (AtPNP-A) can modulate catalase 2 activity

  2020cites this paper
• Discovery of a Nitric Oxide-Responsive Protein in Arabidopsis thaliana

  2019cites this paper
• PlantMP: a database for moonlighting plant proteins

  2019cites this paper
• Seq3seq Fingerprint: Towards End-to-end Semi-supervised Deep Drug Discovery

  2018cites this paper
• GCPred: a web tool for guanylyl cyclase functional centre prediction from amino acid sequence

  2018cites this paper
• Discovery of Novel Functional Centers With Rationally Designed Amino Acid Motifs

  2018influential citation
• Bioinformatic analysis of nucleotide cyclase functional centers and development of ACpred webserver

  2018cites this paper
• Bioinformatic Analysis of Nucleotide Cyclase Functional Centers and Development of ACPred Webserver

  2018cites this paper
• Early Responses to Severe Drought Stress in the Arabidopsis thaliana Cell Suspension Culture Proteome

  2018cites this paper