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The Nucleic Acid Knowledgebase: a new portal for 3D structural information about nucleic acids

Catherine L. Lawson,Helen M Berman,Li Chen,Brinda K. Vallat,Craig L. Zirbel

Published 2023 in Nucleic Acids Research

ABSTRACT

Abstract The Nucleic Acid Knowledgebase (nakb.org) is a new data resource, updated weekly, for experimentally determined 3D structures containing DNA and/or RNA nucleic acid polymers and their biological assemblies. NAKB indexes nucleic acid-containing structures derived from all major structure determination methods (X-ray, NMR and EM), including all held by the Protein Data Bank (PDB). As the planned successor to the Nucleic Acid Database (NDB), NAKB’s design preserves all functionality of the NDB and provides novel nucleic acid-centric content, including structural and functional annotations, as well as annotations from and links to external resources. A variety of custom interactive tools have been developed to enable rapid exploration and drill-down of NAKB’s content.

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