The Role of Vasodilator-stimulated Phosphoproteins in the Development of Malignant Tumors

Vasodilator-stimulated phosphoprotein (VASP) is an actin-binding protein that includes three structural domains: Enabled/VASP homolog1 (EVH1), EVH2, and proline-rich (PRR). VASP plays an important role in various cellular behaviors related to cytoskeletal regulation. More importantly, VASP plays a key role in the progression of several malignant tumors and is associated with malignant cell proliferation, invasion, and metastasis. Here, we have summarized current studies on the impact of VASP on the development of several malignant tumors and their mechanisms. This study provides a new theoretical basis for clinical molecular diagnosis and molecular targeted therapy.

• Publication year

  2023

• Venue

  Current Cancer Drug Targets

• Publication date

  2023-11-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2174/0115680096262439231023110106PMID 37962042PMCID 11092557
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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