3D printed bioabsorbable composite scaffolds of poly (lactic acid)-tricalcium phosphate-ceria with osteogenic property for bone regeneration

S. Harb,Elayaraja Kolanthai,A. S. Pugazhendhi,C. G. Beatrice,L. A. Pinto,Craig J. Neal,E. H. Backes,Ana Carolina C Nunes,Heloisa S. Selistre-de-Araujo,L. C. Costa,Melanie J. Coathup,Sudipta Seal,L. Pessan

Published 2023 in Biomaterials and Biosystems

ABSTRACT

Highlights • The extrusion of filaments produced homogeneous PLA-TCP-CeO2 nanocomposites.• The nanocomposite filament can be stored in ready-to-use composition.• Porous scaffolds were obtained by additive manufacturing.• CeO2 nanoparticles stimulated cell proliferation and differentiation.• Osteogenic PLA-TCP-CeO2 scaffolds are an excellent alternative for bone repair.

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