Improving the outcome of high-risk myeloma (HRMM) is a key therapeutic aim for the next decade. To achieve this aim, it is necessary to understand in detail the genetic drivers underlying this clinical behavior and to target its biology therapeutically. Advances have already been made, with a focus on consensus guidance and the application of novel immunotherapeutic approaches. Cases of HRMM are likely to have impaired prognosis even with novel strategies. However, if disease eradication and minimal disease states are achieved, then cure may be possible.
Approach to High-Risk Multiple Myeloma.
Xiaoyi Chen,Gaurav Varma,Faith Davies,Gareth J Morgan
Published 2024 in Hematology/Oncology Clinics of North America
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- Publication year
2024
- Venue
Hematology/Oncology Clinics of North America
- Publication date
2024-01-01
- Fields of study
Medicine
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- External record
- Source metadata
Semantic Scholar, PubMed
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