Cell death proteins play a central role in host immune signaling during sepsis. These interconnected mechanisms trigger cell demise via apoptosis, necroptosis, and pyroptosis while also driving inflammatory signaling. Targeting cell death mediators with novel therapies may correct the dysregulated inflammation seen during sepsis and improve outcomes for septic patients.
Cell death proteins in sepsis: key players and modern therapeutic approaches
Chloe Yang,C. Coopersmith,John D Lyons
Published 2024 in Frontiers in Immunology
ABSTRACT
PUBLICATION RECORD
- Publication year
2024
- Venue
Frontiers in Immunology
- Publication date
2024-01-11
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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