A generic model of human lifetime exposure to persistent organic contaminants: development and application to PCB-101.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Environmental Pollution

• Publication date

  2000-11-01

• Fields of study

  Medicine, Environmental Science

• Identifiers
  DOI 10.1016/S0269-7491(99)00298-5PMID 15092840
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Clearance of PCDD/Fs via the gastrointestinal tract in occupationally exposed persons.

  1999cited by this paper
• Effects of environmental exposure to polychlorinated biphenyls and dioxins on cognitive abilities in Dutch children at 42 months of age.

  1999cited by this paper
• Methods for the analysis of PCBs in human food, faeces and serum.

  1999cited by this paper
• Input−Output Balance of Polychlorinated Biphenyls in a Long-Term Study of Lactating Dairy Cows

  1999cited by this paper
• PCDD/PCDF: human background data for Germany, a 10-year experience.

  1998cited by this paper
• Temporal trends of organochlorines in Northern Europe, 1967-1995. Relation to global fractionation, leakage from sediments and international measures.

  1998cited by this paper
• Polychlorinated Naphthalenes and Other Organochlorine Contaminants in Swedish Human Milk, 1972–1992

  1998cited by this paper
• Dioxin-like PCBs in the environment-human exposure and the significance of sources.

  1998cited by this paper
• Organochlorine pesticides and polychlorinated biphenyls in human milk of mothers living in northern Germany: current extent of contamination, time trend from 1986 to 1997 and factors that influence the levels of contamination.

  1998cited by this paper
• Digestive tract absorption of PCDD/Fs, PCBs, and HCB in humans: mass balances and mechanistic considerations.

  1998cited by this paper
• Derivation and Field Testing of Air−Milk and Feed−Milk Transfer Factors for PCBs

  1998cited by this paper
• Air-pasture transfer of PCBs.

  1998cited by this paper
• OBSERVATIONS ON PAH, PCB, AND PCDD/F TRENDS IN UK URBAN AIR, 1991-1995

  1997cited by this paper
• Depositional time trends and remobilization of PCBs in lake sediments

  1997cited by this paper
• Food control surveys of polychlorinated dibenzo-p-dioxins and dibenzofurans and intake estimates.

  1997cited by this paper
• 2,3,7,8-Tetrachlorodibenzo-p -dioxin (TCDD) and congeners in infants. A toxicokinetic model of human lifetime body burden by TCDD with special emphasis on its uptake by nutrition

  1997cited by this paper
• A pharmacokinetic analysis of interspecies extrapolation in dioxin risk assessment.

  1997cited by this paper
• Concentrations of blood and hair mercury and serum PCBs in an Ojibwa population that consumes Great Lakes region fish.

  1997cited by this paper
• Polychlorinated biphenyls in UK and Norwegian soils: spatial and temporal trends

  1997cited by this paper
• A generic toxicokinetic model for persistent lipophilic compounds in humans: an application to TCDD.

  1996cited by this paper
• Dioxins in the Environment: A Review of Trend Data

  1996cited by this paper
• Factors that influence the level of contamination of human milk with poly-chlorinated organic compounds

  1996cited by this paper
• PCDDs, PCDFs, and PCBs in human milk from different parts of Norway and Lithuania.

  1995cited by this paper
• The influence of multiple sewage sludge amendments on the PCB content of an agricultural soil over time

  1995cited by this paper
• Mono-ortho- and non-ortho-substituted polychlorinated biphenyls in human milk from Mohawk and control women: Effects of maternal factors and previous lactation

  1994cited by this paper
• Determination of PCB Metabolic, Excretion, and Accumulation Rates for Use as Indicators of Biological Response and Relative Risk.

  1994cited by this paper
• PCBs and other organochlorines in human tissue samples from the Welsh population: I--Adipose.

  1994cited by this paper
• PCDD and PCDF exposure and levels in humans in Germany.

  1994cited by this paper
• Modeling long-term exposure of the whole population to chemicals in food.

  1993cited by this paper
• Dioxins in the Environment

  1985cited by this paper
• Organochlorine pesticide residues in human fat in the United Kingdom 1976-7.

  1972cited by this paper
• Agriculture, Fisheries and Food

  1962cited by this paper

• A simplified model for simulating lifetime accumulation of persistent organic pollutants in humans with steady-state identification.

  2025cites this paper
• Organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in adipose tissue of women from Grand Tunis and their association with demographic factors and dietary habits.

  2023cites this paper
• Multi residue analysis of organochlorine pesticides in fish, milk, egg and their feed by GC-MS/MS and their impact assessment on consumers health in Bangladesh

  2022cites this paper
• Persistent pollutants in fresh and abandoned eggs of Common Tern (Sterna hirundo) and Arctic Tern (Sterna paradisaea) in Ireland.

  2021cites this paper
• Impact of sociodemographic profile, generation and bioaccumulation on lifetime dietary and internal exposures to PCBs.

  2021cites this paper
• Dietary risk assessment methodology: how to deal with changes through life

  2020cites this paper
• A Two-Step Gas Chromatography-Tandem Mass Spectrometry Method for Measurement of Multiple Environmental Pollutants in Human Plasma

  2020cites this paper
• Dynamics of PCB exposure in the past 50 years and recent high concentrations in human breast milk: Analysis of influencing factors using a physiologically based pharmacokinetic model.

  2019cites this paper
• Persistent Organic Pollutants and Breast Cancer: A Systematic Review and Critical Appraisal of the Literature

  2019cites this paper
• Mechanistically Modeling Human Exposure to Persistent Organic Pollutants

  2019cites this paper
• A nested case‐control study of polychlorinated biphenyls, organochlorine pesticides, and thyroid cancer in the Janus Serum Bank cohort

  2018cites this paper
• Risk assessment of some residues in milk and some dairy products

  2018cites this paper
• Predicting human plasma concentrations of persistent organic pollutants from dietary intake and socio-demographic information in the Norwegian Women and Cancer study.

  2018cites this paper
• Revisiting the Contributions of Far- and Near-Field Routes to Aggregate Human Exposure to Polychlorinated Biphenyls (PCBs).

  2018cites this paper
• Draft Mechanistic modeling of persistent organic pollutant exposure among Indigenous Arctic populations : motivations , challenges , and benefits

  2017cites this paper
• Temporal trends of polychlorinated biphenyls serum levels in subjects living in a highly polluted area from 2003 to 2015: a follow-up study.

  2017cites this paper
• Mechanistic modeling of persistent organic pollutant exposure among indigenous Arctic populations: motivations, challenges, and benefits

  2017cites this paper
• Perspective on pre- and post-natal agro-food exposure to persistent organic pollutants and their effects on quality of life.

  2017cites this paper
• Historical human exposure to perfluoroalkyl acids in the United States and Australia reconstructed from biomonitoring data using population-based pharmacokinetic modelling.

  2017cites this paper
• The impacts of emission trends of POPs on human concentration dynamics: Lessons learned from a longitudinal study in Norway (1979-2007).

  2017influential citation
• PAPER I Maternal serum concentrations of per- and polyfluoroalkyl substances and their predictors in years with reduced production and use

  2016cites this paper
• Modelling ecological and human exposure to POPs in Venice lagoon. Part I - Application of MERLIN-Expo tool for integrated exposure assessment.

  2016cites this paper
• Niveles de plaguicidas organoclorados en suero sanguíneo comparados con la concentración de lípidos sanguíneos

  2015cites this paper
• Combining plasma measurements and mechanistic modeling to explore the effect of POPs on type 2 diabetes mellitus in Norwegian women.

  2015cites this paper
• Estimating Time-Varying PCB Exposures Using Person-Specific Predictions to Supplement Measured Values: A Comparison of Observed and Predicted Values in Two Cohorts of Norwegian Women

  2015cites this paper
• Estimated daily intake of organochlorine pesticides from dairy products in Brazil

  2015cites this paper
• The use of biomonitoring equivalents for interpreting blood concentrations in population studies: a case for polychlorinated biphenyls

  2015cites this paper
• Historical intake and elimination of polychlorinated biphenyls and organochlorine pesticides by the Australian population reconstructed from biomonitoring data.

  2015influential citation
• Current trends and projections in the utilisation rates of hip and knee replacement in New Zealand from 2001 to 2026.

  2014cites this paper
• Estimated infant intake of persistent organic pollutants through breast milk in New Zealand.

  2014cites this paper
• Priority persistent contaminants in people dwelling in critical areas of Campania Region, Italy (SEBIOREC biomonitoring study).

  2014cites this paper
• Enhanced elimination of perfluorooctane sulfonic acid by menstruating women: evidence from population-based pharmacokinetic modeling.

  2014cites this paper
• Maternal serum concentrations of per- and polyfluoroalkyl substances and their predictors in years with reduced production and use.

  2014cites this paper
• Improving our Understanding of Bioaccumulation in Humans, Fish and Surrogate Lipid Systems

  2013influential citation
• Estimation of health risk by using toxicokinetic modelling: a case study of polychlorinated biphenyl PCB153.

  2013cites this paper
• Bounding uncertainties in intrinsic human elimination half-lives and intake of polybrominated diphenyl ethers in the North American population.

  2013cites this paper
• Incidencia de la dieta y factores socio-demográficos sobre los niveles de contaminantes orgánicos persistentes (COPs) en leche materna de poblaciones urbanas y rurales de Argentina

  2013cites this paper
• Analysis of human milk to assess exposure to PAHs, PCBs and organochlorine pesticides in the vicinity Mediterranean city Mersin, Turkey.

  2012cites this paper
• Estimation of human body concentrations of DDT from indoor residual spraying for malaria control.

  2012cites this paper
• Interpreting PCB levels in breast milk using a physiologically based pharmacokinetic model to reconstruct the dynamic exposure of Italian women

  2012cites this paper
• Understanding Differences in the Body Burden–Age Relationships of Bioaccumulating Contaminants Based on Population Cross Sections versus Individuals

  2012cites this paper
• Investigating Intergenerational Differences in Human PCB Exposure due to Variable Emissions and Reproductive Behaviors

  2010influential citation
• Integrated analysis of halogenated organic pollutants in sub-millilitre volumes of venous and umbilical cord blood sera

  2010cites this paper
• Intrinsic Human Elimination Half-Lives of Polychlorinated Biphenyls Derived from the Temporal Evolution of Cross-Sectional Biomonitoring Data from the United Kingdom

  2010cites this paper
• A Multi-Individual Pharmacokinetic Model Framework for Interpreting Time Trends of Persistent Chemicals in Human Populations: Application to a Postban Situation

  2009cites this paper
• Dichlorodiphenyldichloroethane and Polychlorinated Biphenyls: Intraindividual Changes, Correlations, and Predictors in Healthy Women from the Southeastern United States

  2008cites this paper
• Environmental Science Computing

  2008cites this paper
• Serum persistent organic pollutants and prostate cancer risk

  2008cites this paper
• Evaluation of human exposure to arsenic due to rice ingestion in the vicinity of abandoned Myungbong Au–Ag mine site, Korea

  2008cites this paper
• Measuring transfer of 14C-PCB from maternal diet to milk in a goat model using an accelerator mass spectrometer (AMS)

  2007cites this paper
• Risk Assessment of Heavy Metals in the Vicinity of the Abandoned Metal Mine Areas

  2007cites this paper
• In utero and post-natal accumulation of organochlorine compounds in children under different environmental conditions.

  2007cites this paper
• DDE and PCBs: Intra-individual changes, correlations, predictors and role in timing of menopause

  2007cites this paper
• Assessment of polychlorinated biphenyls (PCBs) in cheese from Rio Grande do Sul, Brazil.

  2006cites this paper
• Body burden of dioxins and dioxin-like polychlorinated biphenyls in pregnant women residing in a contaminated area.

  2006cites this paper
• Human risk assessment of As, Cd, Cu and Zn in the abandoned metal mine site

  2005cites this paper
• Direct observation of organic contaminant uptake, storage, and metabolism within plant roots.

  2005cites this paper
• Alkyl Phenols and Diethylhexyl Phthalate in Tissues of Sheep Grazing Pastures Fertilized with Sewage Sludge or Inorganic Fertilizer

  2005cites this paper
• Environmental health impacts: occurrence, exposure and significance, Lancaster University, UK, 9-10 September 2003.

  2004cites this paper
• Some Considerations About Bioindicators in Environmental Monitoring

  2004cites this paper
• Organochlorine Exposure and Colorectal Cancer Risk

  2004cites this paper
• Relationship Between Age and Levels of Organochlorine Contaminants in Human Serum of a Belgian Population

  2002cites this paper
• An input-output balance study for PCBs in humans.

  2002cites this paper
• The global distribution of PCBs and organochlorine pesticides in butter.

  2001cites this paper
• Human exposure to PCDD/Fs in the UK: the development of a modelling approach to give historical and future perspectives.

  2000cites this paper