Slower speed of blood pressure recovery after standing is associated with accelerated brain aging: Evidence from The Irish Longitudinal Study on Ageing (TILDA)

Morgana A. Shirsath,J. O’Connor,R. Boyle,L. Newman,S. Knight,B. Hernández,R. Whelan,James F M Meaney,R. Kenny

Published 2024 in Cerebral Circulation - Cognition and Behavior

ABSTRACT

Highlights • Impaired recovery of systolic and diastolic blood pressure after standing is associated with accelerated brain ageing, determined using the BrainPAD model.• No association was found between heart rate recovery and brain age acceleration.• Evaluation of the response of blood pressure to active standing may be an indicator of brain health, and accelerated brain ageing.

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