Incidence, Species Distribution, and Antifungal Susceptibility of Candida Bloodstream Infections in a Tertiary Algerian Hospital

Assia Meradji,S. Ranque,Fayza Bachtarzi,Nabil Mosbah,Tayeb Moulahem

Published 2023 in ECM 2023

ABSTRACT

: Candida infections are the most frequent invasive fungal diseases. To date, few studies have been conducted on candidemia in Algeria. The aim of this study was to assess the incidence, species distribution, and antifungal susceptibility for Candida bloodstream infections. This prospective, monocentric study covered all cases of candidemia diagnosed in the ICU at Setif hospital in Algeria. Yeast isolates were identified using MALDI TOF. Antifungal susceptibility testing was performed using Sensititre YeastOne. The incidence rate was 7.03 cases per admission in the ICU. Five Candida species were isolated: C. albicans , C. glabrata , C. parapsilosis , C. tropicalis and C. pelliculosa . Overall, 78.6% of isolates were sensitive to all antifungals.

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