ABSTRACT Intrahepatic cholestasis of pregnancy is an intrahepatic etiology of acute cholestasis commonly defined by pruritus and increased bile acids, liver transaminases, and, occasionally, bilirubin. Azathioprine is an immunosuppressive agent associated with various forms of hepatoxicity, ranging from transient rises in serum aminotransferase levels, acute cholestatic injury, and chronic hepatic injury. In this report, we present a 20-year-old pregnant woman who presented with cholestatic liver injury due to intrahepatic cholestasis of pregnancy with a clinical picture complicated by increased levels of azathioprine metabolites.
Atypical Intrahepatic Cholestasis of Pregnancy: A Red Herring
Blake H. Bentley,Alexa Cecil,William C. Lippert
Published 2024 in ACG Case Reports Journal
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- Publication year
2024
- Venue
ACG Case Reports Journal
- Publication date
2024-04-01
- Fields of study
Medicine
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Semantic Scholar, PubMed
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