The FGF6 amplification mutation plays an important role in the progression and treatment of malignant meningioma

Ruihao Liang,Binhua Tan,Kai Lei,Ke Xu,Jialu Liang,Jing Huang,Yicheng Liang,Jintao Huang,Liwen Zhang,Xiaoliang Shi,Zhi‐qiang Lv,Huayue Lin,Minghui Wang

Published 2024 in Translational Oncology

ABSTRACT

Highlights • A rare case of primary mediastinal malignant meningioma was reported.• Gene sequencing and clonal evolution analysis can help to find suitable therapeutic targets.• FGF6 amplification mutation can promote the progression of malignant meningioma.• FGF6 gene amplification may be a target for using anlotinib.

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