Disruption of Rpn4-Induced Proteasome Expression in Saccharomyces cerevisiae Reduces Cell Viability Under Stressed Conditions

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Genetics

• Publication date

  2008-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1534/genetics.108.094524PMID 18832351PMCID PMC2600933
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• [A cryptic protease couples deubiquitination and degradation by the proteasome].

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  2000cited by this paper
• Physical association of ubiquitin ligases and the 26S proteasome.

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• The 26S proteasome: a molecular machine designed for controlled proteolysis.

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• Subcellular Localization, Stoichiometry, and Protein Levels of 26 S Proteasome Subunits in Yeast*

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• Son1p is a component of the 26S proteasome of the yeast Saccharomyces cerevisiae

  1998cited by this paper
• Evidence that mating by the Saccharomyces cerevisiae gpa1Val50 mutant occurs through the default mating pathway and a suggestion of a role for ubiquitin-mediated proteolysis.

  1997cited by this paper
• Copyright © 1998, American Society for Microbiology The Regulatory Particle of the Saccharomyces cerevisiae Proteasome

  1997cited by this paper
• A Proteolytic Pathway That Recognizes Ubiquitin as a Degradation Signal (*)

  1995cited by this paper
• S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase

  1993influential reference

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