Cultivation of immortalized human hepatocytes HepZ on macroporous CultiSpher G microcarriers.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Biotechnology and Bioengineering

• Publication date

  2000-04-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/(SICI)1097-0290(20000405)68:1<59::AID-BIT7>3.0.CO;2-NPMID 10699872
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Microcarrier cultivation of bovine aortic endothelial cells in spinner vessels and a membrane stirred bioreactor

  2004cited by this paper
• Scale up cultivation of primary human umbilical vein endothelial cells on microcarriers from spinner vessels to bioreactor fermentation

  2004cited by this paper
• Optimization of serum-free fermentation processes for antibody production

  2004cited by this paper
• Evaluation of a novel bioartificial liver in rats with complete liver ischemia: treatment efficacy and species-specific alpha-GST detection to monitor hepatocyte viability.

  1999cited by this paper
• Infection of human cells by an endogenous retrovirus of pigs

  1997cited by this paper
• Functional recovery of porcine hepatocytes after hypothermic or cryogenic preservation for liver support systems.

  1997cited by this paper
• Improvement of serum amino acid profile in hepatic failure with the bioartificial liver using multicellular hepatocyte spheroids

  1996cited by this paper
• Development of a Hybrid Liver Support System: A Review

  1996cited by this paper
• Use of mammalian liver cells for artificial liver support.

  1996cited by this paper
• Establishment of a human hepatocyte line derived from primary culture in a collagen gel sandwich culture system.

  1995cited by this paper
• Hybrid liver support system in a short term application on hepatectomized pigs

  1994cited by this paper
• Is the biological artificial liver clinically applicable? A historic review of biological artificial liver support systems.

  1994cited by this paper
• Isolated hepatocytes in a bioartificial liver: A single group view and experience

  1994cited by this paper
• Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver.

  1994cited by this paper
• Extracorporeal liver support. Application to fulminant hepatic failure.

  1994cited by this paper
• Immunologic considerations in the use of cultured porcine hepatocytes as a hybrid artificial liver. Anti-porcine hepatocyte human serum.

  1993cited by this paper
• Evaluation of a hepatocyte‐entrapment hollow fiber bioreactor: A potential bioartificial liver

  1993cited by this paper
• Development of a Hybrid Bioartificial Liver

  1993cited by this paper
• Use of a novel bioartificial liver in a patient with acute liver insufficiency.

  1993cited by this paper
• Performance of plasma-perfused, microencapsulated hepatocytes: prospects for extracorporeal liver support.

  1993cited by this paper
• Microcarrier culture of hepatocytes in whole plasma for use in liver support bioreactors.

  1992cited by this paper
• Hepatocyte function in a hollow fiber bioreactor: a potential bioartificial liver.

  1992cited by this paper
• Assessment of Artificial Liver Support Technology

  1992cited by this paper
• Reversal of fulminant hepatic failure using an extracorporeal liver assist device

  1992cited by this paper
• Microcarrier culture of hepatocytes in whole plasma for use in liver support bioreactors.

  1992cited by this paper
• Cellular immortalization--an essential step or merely a risk factor in DNA virus-induced transformation?

  1990cited by this paper
• Lignocaine metabolite formation as a measure of pre-transplant liver function.

  1989cited by this paper
• Bubble free cell culture aeration with porous moving membranes.

  1987cited by this paper
• Monoethylglycinexylidide Formation Kinetics: A Novel Approach to Assessment of Liver Function

  1987cited by this paper
• Preparation of rat liver cells. 3. Enzymatic requirements for tissue dispersion.

  1973cited by this paper
• A low-viscosity epoxy resin embedding medium for electron microscopy.

  1969cited by this paper
• THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

  1963cited by this paper

• Towards Biomanufacturing of Cell-Derived Matrices

  2021cites this paper
• A Critical Perspective on 3D Liver Models for Drug Metabolism and Toxicology Studies

  2021cites this paper
• Hepatic tissue engineering

  2020cites this paper
• Liver Tissue Engineering

  2020cites this paper
• Fabrication and in vitro evaluation of a packed-bed bioreactor based on an optimum two-stage culture strategy.

  2019cites this paper
• Expansion of Transdifferentiated Human Hepatocytes in a Serum-Free Microcarrier Culture System

  2019cites this paper
• Liver Tissue Engineering

  2018cites this paper
• Organic-polymeric radial flow biorreactor for liver models

  2016cites this paper
• Complex Assessment of Functional Activity of Chang Liver Cell Culture in blood serum of Patients with Liver Diseases of Various Etiology

  2015cites this paper
• Development and characterization of a new human hepatic cell line

  2015cites this paper
• Complex Assessment of Functional Activity of Chang liver Cell Culture in Blood Serum of Patients with Liver Diseases of Various Etiology

  2015cites this paper
• Strategies for immortalization of primary hepatocytes.

  2014cites this paper
• Evolution of BiorEactors for ExtracorporEal livEr support

  2014cites this paper
• Evaluation of macroporous and microporous carriers for CHO-K1 cell growth and monoclonal antibody production.

  2013cites this paper
• Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering.

  2013cites this paper
• Attachment of Embryonic Stem Cells-derived Cardiomyocytes in Cultispher-S Microcarriers by using Spinner flask

  2012cites this paper
• Use of decellularized porcine liver for engineering humanized liver organ.

  2012cites this paper
• Proliferative human cell sources applied as biocomponent in bioartificial livers: a review

  2012cites this paper
• Key challenges to the development of extracorporeal bioartificial liver support systems.

  2012cites this paper
• The Continuum of Health Risk Assessments

  2012cites this paper
• UvA-DARE ( Digital Academic Repository ) Human liver cell lines for the AMC-bioartificial liver

  2012cites this paper
• Human liver cell lines for the AMC-bioartificial liver

  2012cites this paper
• Molecular and Cellular Mechanisms of the Angiogenic Effect of Poly(methacrylic acid-co-methyl methacrylate) Beads

  2012cites this paper
• Porous Poly(Lactic-Co-Glycolic Acid) Microsphere as Cell Culture Substrate and Cell Transplantation Vehicle

  2012cites this paper
• New Models for the In Vitro Study of Liver Toxicity: 3D Culture Systems and the Role of Bioreactors

  2012cites this paper
• Cell expansion of human articular chondrocytes on macroporous gelatine scaffolds—impact of microcarrier selection on cell proliferation

  2011cites this paper
• Effectiveness factor and diffusion limitations in collagen gel modules containing HepG2 cells

  2011influential citation
• Cell microcarriers and microcapsules of stimuli-responsive polymers.

  2011cites this paper
• Factors effects the Gr owth of Chinese Hamster Ovary (CHO) cell on Microcarriers Culture

  2010cites this paper
• Microcarriers and Their Potential in Tissue Regeneration

  2010cites this paper
• Bioartificial liver support systems.

  2010cites this paper
• Hepatic Maturation of Human Fetal Hepatocytes in Four-Compartment Three-Dimensional Perfusion Culture

  2009cites this paper
• Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood‐derived biological glues in vitro

  2009cites this paper
• Porous Poly(Lactic-Co-Glycolic Acid) Microsphere as Cell Culture Substrate and Cell Transplantation Vehicle for Adipose Tissue Engineering

  2008cites this paper
• Cell Attachment to Microcarriers Affects Growth, Metabolic Activity, and Culture Productivity in Bioreactor Culture

  2008cites this paper
• Towards application of a human liver cell line for use in the AMC bioartificial liver

  2007cites this paper
• Functional and morphological comparison of three primary liver cell types cultured in the AMC bioartificial liver

  2007cites this paper
• Employing human keratinocytes cultured on macroporous gelatin spheres to treat full thickness-wounds: an in vivo study on athymic rats.

  2007cites this paper
• Metabolic rate does not scale with body mass in cultured mammalian cells.

  2007cites this paper
• 12 – Cellular Transplants for Liver Diseases

  2007cites this paper
• Oxygen transport within a hepatic hollow fiber bioreactor

  2007cites this paper
• In vitro and in vivo studies on biodegradable matrices for autotransplantation

  2006cites this paper
• Oncostatin M stimulates proliferation and functions of mouse fetal liver cells in three‐dimensional cultures

  2005cites this paper
• Neue Anwendungsmethoden der Durchflusszytometrie in der Biotechnologie

  2005cites this paper
• Porcine acute liver failure model established by two-phase surgery and treated with hollow fiber bioartificial liver support system.

  2005cites this paper
• Cell-based models to study hepatic drug metabolism and enzyme induction in humans

  2005cites this paper
• Cell culture technology for pharmaceutical and cell-based therapies

  2005cites this paper
• Development of a Microbiosensor Based on Fish Chromatophores Immobilized on Ferromagnetic Gelatin Beads

  2005cites this paper
• Three-dimensional high-density culture of HepG2 cells in a 5-ml radial-flow bioreactor for construction of artificial liver.

  2005cites this paper
• Cellular therapies for liver replacement.

  2004cites this paper
• Extracorporeal Liver Support: Waiting for the Deciding Vote

  2003cites this paper
• Using PC12 Cells To Evaluate Poly(caprolactone) and Collagenous Microcarriers for Applications in Nerve Guide Fabrication

  2003cites this paper
• Animal Cell Types, Liver Cells

  2003cites this paper
• Using PC12 cells and rat cortical neurons to evaluate poly(caprolactone) and collagenous microcarriers for applications in nerve guide fabrication

  2003cites this paper
• In Vitro Expansion of Human Hepatocytes is Restricted by Telomere-Dependent Replicative Aging

  2003cites this paper
• Recent Developments on Human Cell Lines for the Bioartificial Liver

  2002cites this paper
• Bioreactor developments for tissue engineering applications by the example of the bioartificial liver.

  2002cites this paper
• Improving the next generation of bioartificial liver devices.

  2002cites this paper
• Design and development of a novel textile composite scaffold bioreactor for application as bioartificial liver support device

  2002cites this paper
• Optical waveguide lightmode spectroscopy (OWLS) to monitor cell proliferation quantitatively.

  2002cites this paper
• Engineering Liver Therapies for the Future

  2002cites this paper
• Obtenção de antígeno viral a partir de culturas de células vero em microcarregadores porosos

  2001cites this paper
• Advances in bioartificial liver devices

  2001cites this paper
• Cellular Physiology Cellular Physiology Cellular Physiology Cellular Physiology Cellular Physiology Entrapment of Embryonic Stem Cells-derived Cardiomyocytes in Macroporous Biodegradable Microspheres: Preparation and Characterization Contributed Equally to the Study and Thus Share First Authorship K

  year unknowncites this paper