Glial Cell–Derived Cytokines Attenuate the Breakdown of Vascular Integrity in Diabetic Retinopathy

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Diabetes

• Publication date

  2007-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2337/db06-1431PMID 17470563
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

  2006cited by this paper
• VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis

  2006cited by this paper
• Glyceraldehyde-derived advanced glycation end-products preferentially induce VEGF expression and reduce GDNF expression in human astrocytes.

  2005cited by this paper
• Expression of the Retinoic Acid-Metabolizing Enzyme CYP26A1 Limits Programmed Cell Death

  2005cited by this paper
• Glial cell line-derived neurotrophic factor in the vitreous of patients with proliferative diabetic retinopathy.

  2005cited by this paper
• Nonsteroid Nuclear Receptors : What Are Genetic Studies Telling Us about Their Role in Real Life ? Review

  2004cited by this paper
• Transcription factors having impact on vascular endothelial growth factor (VEGF) gene expression in angiogenesis.

  2004cited by this paper
• Pharmacotherapy for diabetic retinopathy

  2004cited by this paper
• Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling

  2004cited by this paper
• Enhanced gene activation by Notch and BMP signaling cross-talk.

  2003cited by this paper
• Tight junctions and human diseases

  2003cited by this paper
• The GDNF family: Signalling, biological functions and therapeutic value

  2002cited by this paper
• Signaling crosstalk underlying synergistic induction of astrocyte differentiation by BMPs and IL‐6 family of cytokines

  2001cited by this paper
• [Diabetic retinopathy].

  2001cited by this paper
• Expression of GFRalpha-1, receptor for GDNF, in rat brain capillary during postnatal development of the BBB.

  2000cited by this paper
• Regulation of Glial Cell Line-Derived Neurotrophic Factor Responsiveness in Developing Rat Sympathetic Neurons by Retinoic Acid and Bone Morphogenetic Protein-2

  2000influential reference
• Expression of receptors for glial cell line-derived neurotrophic factor (GDNF) and neurturin in the inner blood-retinal barrier of rats.

  2000cited by this paper
• Activation of retinoic acid receptor alpha is sufficient for full induction of retinoid responses in SK-BR-3 and T47D human breast cancer cells.

  2000cited by this paper
• Glial cell line-derived neurotrophic factor induces barrier function of endothelial cells forming the blood-brain barrier.

  1999cited by this paper
• GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF.

  1996cited by this paper
• Localization of 7H6 tight junction-associated antigen along the cell border of vascular endothelial cells correlates with paracellular barrier function against ions, large molecules, and cancer cells.

  1996cited by this paper
• The relation between expression of vascular endothelial growth factor and breakdown of the blood-retinal barrier in diabetic rat retinas.

  1996cited by this paper
• Characterization of a multicomponent receptor for GDNF

  1996cited by this paper
• GDNF–Induced Activation of the Ret Protein Tyrosine Kinase Is Mediated by GDNFR-α, a Novel Receptor for GDNF

  1996cited by this paper
• The RXR heterodimers and orphan receptors.

  1995cited by this paper
• Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization.

  1995cited by this paper
• Diabetic retinopathy

  1995cited by this paper
• Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

  1995cited by this paper
• Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life?

  1995cited by this paper
• Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders.

  1994cited by this paper
• GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle.

  1994cited by this paper
• The Retinoids : biology, chemistry, and medicine

  1994cited by this paper
• GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons.

  1993cited by this paper
• Selective high affinity retinoic acid receptor alpha or beta-gamma ligands.

  1991cited by this paper
• Tumor cells secrete a vascular permeability factor that promotes accumulation of ascites fluid.

  1983cited by this paper
• The induction of differentiation in teratocarcinoma stem cells by retinoic acid.

  1978cited by this paper

• L-DOPA treatment promotes sustained neurovascular and synaptic homeostasis in the diabetic retina

  2026cites this paper
• Diabetic Retinopathy, a Comprehensive Overview on Pathophysiology and Relevant Experimental Models

  2025cites this paper
• The Breakdown of Neurovascular Barriers: Molecular Mechanisms of Tight Junction Dysfunction

  2025cites this paper
• Crosstalk Between Neuronal and Glial Cells in Diabetic Retinopathy: Mechanisms and Implications for Neurodegeneration

  2025cites this paper
• Müller cells trophism and pathology as the next therapeutic targets for retinal diseases.

  2025cites this paper
• Association of inflammatory cytokines with type 2 diabetes mellitus and diabetic nephropathy: a bidirectional Mendelian randomization study

  2024cites this paper
• IL‐10‐induced modulation of macrophage polarization suppresses outer‐blood‐retinal barrier disruption in the streptozotocin‐induced early diabetic retinopathy mouse model

  2024cites this paper
• Association of circulating inflammatory proteins with type 2 diabetes mellitus and its complications: a bidirectional Mendelian randomization study

  2024cites this paper
• Lactylation-driven FTO targets CDK2 to aggravate microvascular anomalies in diabetic retinopathy

  2024cites this paper
• Unexpected and Synergistical Effects of All-Trans Retinoic Acid and TGF-β2 on Biological Aspects of 2D and 3D Cultured ARPE19 Cells

  2024cites this paper
• Lactylation-driven FTO-mediated m6A modification of CDK2 aggravates diabetic microvascular anomalies

  2023cites this paper
• Automated Measurement of Transepithelial Electrical Resistance (TEER) in 96-Well Transwells using ECIS TEER96: Single and Multiple Time Point Assessments.

  2023cites this paper
• The Role of Cytokines in the Pathogenesis of Diabetic Macular Edema

  2023cites this paper
• All Trans-Retinoic Acids Facilitate the Remodeling of 2D and 3D Cultured Human Conjunctival Fibroblasts

  2022cites this paper
• Retinoid signaling regulates angiogenesis and blood‐retinal barrier integrity in neonatal mouse retina

  2022cites this paper
• Genetic Modification as a New Approach to Ameliorate the Therapeutic Efficacy of Stem Cells in Diabetic Retinopathy

  2022cites this paper
• Comprehensive assessment of growth factors, inflammatory mediators, and cytokines in vitreous from patients with proliferative diabetic retinopathy.

  2022cites this paper
• All-trans Retinoic Acids Synergistically and Beneficially Affect In Vitro Glaucomatous Trabecular Meshwork (TM) Models Using 2D and 3D Cell Cultures of Human TM Cells

  2022cites this paper
• Microglia-derived TNF-α mediates Müller cell activation by activating the TNFR1-NF-κB pathway.

  2021cites this paper
• Serum levels of glial cell line-derived neurotrophic factor as a biomarker for mood disorders and lithium response.

  2021cites this paper
• Eyeing the Extracellular Matrix in Vascular Development and Microvascular Diseases and Bridging the Divide between Vascular Mechanics and Function

  2020cites this paper
• Association Between Pathophysiological Mechanisms of Diabetic Retinopathy and Parkinson’s Disease

  2020cites this paper
• Clinical Strategies in the Management of Diabetic Retinopathy

  2019cites this paper
• Vitreous IL-8 and VEGF levels in diabetic macular edema with or without subretinal fluid

  2019cites this paper
• Development and characterization of an in vitro system of the human retina using cultured cell lines

  2019cites this paper
• The role of the retinal pigment epithelium and Müller cells secretome in neovascular retinal pathologies.

  2018cites this paper
• Retinoic acid signaling is essential for maintenance of the blood‐retinal barrier

  2018cites this paper
• Diabetic Macular Edema

  2018cites this paper
• Interaction between microglia and retinal pigment epithelial cells determines the integrity of outer blood‐retinal barrier in diabetic retinopathy

  2018cites this paper
• Ranibizumab in the Treatment of Diabetic Macular Edema: A Review of the Current Status, Unmet Needs, and Emerging Challenges

  2017cites this paper
• Diabetic Macular Edema

  2017cites this paper
• Role of glial cell line-derived neurotrophic factor in the pathogenesis and treatment of mood disorders

  2017cites this paper
• Cellular retinoic acid bioavailability in various pathologies and its therapeutic implication

  2017cites this paper
• Neurotrophin receptor agonists and antagonists as therapeutic agents: An evolving paradigm.

  2017cites this paper
• Neurotrophic factors (BDNF and GDNF) and the serotonergic system of the brain

  2017cites this paper
• Diabetes Impairs the Aldehyde Detoxifying Capacity of the Retina.

  2016cites this paper
• The importance of glial cells in the homeostasis of the retinal microenvironment and their pivotal role in the course of diabetic retinopathy.

  2016cites this paper
• LOCAL AND SYSTEMIC VEGF-А PRODUCTION IN COMPLICATED PROLIFERATIVE DIABETIC RETINOPATHY

  2016cites this paper
• Pharmakotherapie und Humanpharmakologische Untersuchungen bei Patienten mit DME (Diabetisches Makulaödem) und PDR (Proliferative Diabetische Retinopathie) anhand klinischer Parameter und inflammatorischer Biomarker

  2016cites this paper
• Vasoregression: A Shared Vascular Pathology Underlying Macrovascular And Microvascular Pathologies?

  2015cites this paper
• The clinical utility of aflibercept for diabetic macular edema

  2015cites this paper
• Pathophysiology of Macular Edema: Results from Basic Research

  2015cites this paper
• The Blood-Retinal Barrier

  2015cites this paper
• Role of Reactive Gliosis and Neuroinflammation in Experimental Glaucoma

  2015cites this paper
• Targets and Therapy The clinical utility of aflibercept for diabetic macular edema

  2015cites this paper
• Diabetes and Retinal Vascular Dysfunction

  2014cites this paper
• Neuropeptides, trophic factors, and other substances providing morphofunctional and metabolic protection in experimental models of diabetic retinopathy.

  2014cites this paper
• MACULAR HYPOTROPHY AFTER INTERNAL LIMITING MEMBRANE REMOVAL FOR DIABETIC MACULAR EDEMA

  2014cites this paper
• GDNF is Involved in the Barrier-Inducing Effect of Enteric Glial Cells on Intestinal Epithelial Cells Under Acute Ischemia Reperfusion Stimulation

  2014cites this paper
• Mesenchymal Stem Cells: New Players in Retinopathy Therapy

  2014cites this paper
• Human Retinal Transmitochondrial Cybrids with J or H mtDNA Haplogroups Respond Differently to Ultraviolet Radiation: Implications for Retinal Diseases

  2014cites this paper
• Role of microRNAs in the modulation of diabetic retinopathy.

  2014cites this paper
• Anti-VEGF Therapy for the Management of Diabetic Macular Edema

  2013cites this paper
• Adeno-Associated Virus Mediated Delivery of a Non-Membrane Targeted Human Soluble CD59 Attenuates Some Aspects of Diabetic Retinopathy in Mice

  2013cites this paper
• AAV-Mediated, Optogenetic Ablation of Müller Glia Leads to Structural and Functional Changes in the Mouse Retina

  2013cites this paper
• Vascular endothelial growth factor trap-eye (Aflibercept) for the management of diabetic macular edema.

  2013cites this paper
• Tight junction‐related human diseases

  2013cites this paper
• Chapter 17 – Cell Biology of the Müller Cell

  2013cites this paper
• Neuroretinal activation in diabetes mellitus

  2013cites this paper
• Current and new concepts in the diagnosis and management of diabetic macular oedema

  2013cites this paper
• New functions of Müller cells

  2013cites this paper
• Tamibarotene: a candidate retinoid drug for Alzheimer's disease.

  2012cites this paper
• Glial Cell–Derived Cytokines and Vascular Integrity in Diabetic Retinopathy

  2012cites this paper
• Inflammation and Angiogenesis in Diabetic Retinopathy 165 types in the retina in diabetes

  2012cites this paper
• Expression of Glial Cell Line‐Derived Neurotrophic Factor and its Receptors in Cultured Retinal Müller Cells Under High Glucose Circumstance

  2012cites this paper
• Reduction of experimental diabetic vascular leakage and pericyte apoptosis in mice by delivery of αA-crystallin with a recombinant adenovirus

  2012cites this paper
• Pericyte-derived Glial Cell Line-derived Neurotrophic Factor Increase the Expression of Claudin-5 in the Blood–brain Barrier and the Blood-nerve Barrier

  2012cites this paper
• Inflammation and Angiogenesis in Diabetic Retinopathy

  2012cites this paper
• Resveratrol blocks diabetes‐induced early vascular lesions and vascular endothelial growth factor induction in mouse retinas

  2012cites this paper
• The DA VINCI Study: phase 2 primary results of VEGF Trap-Eye in patients with diabetic macular edema.

  2011cites this paper
• Carotenoids and Alzheimer's disease: an insight into therapeutic role of retinoids in animal models.

  2011cites this paper
• Advanced glycation end products and diabetic retinopathy

  2011cites this paper
• Müller Glial Cells in Retinal Disease

  2011cites this paper
• Amelioration of Oxidative Stress in Mouse Model of Diabetic Retinopathy by Arnebia benthamii

  2011cites this paper
• Integrating pathway analysis and genetics of gene expression for genome-wide association studies.

  2010cites this paper
• Validation of structural and functional lesions of diabetic retinopathy in mice

  2010cites this paper
• Emerging novel treatment strategies for diabetic eye diseases.

  2010cites this paper
• Treatment‐induced diabetic neuropathy: A reversible painful autonomic neuropathy

  2010cites this paper
• Diabetic Macular Edema

  2010cites this paper
• Longitudinal in vivo imaging of retinal gliosis in a diabetic mouse model.

  2010cites this paper
• Diabetic macular edema: pathogenesis and treatment.

  2009influential citation
• Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embryonic stem cells in a rat model of retinal degeneration

  2009cites this paper
• Towards Retinoid Therapy for Alzheimer’s Disease

  2009cites this paper
• Current literature in diabetes

  2008cites this paper
• Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9

  2008cites this paper
• Trophic factors and neuronal interactions regulate the cell cycle and Pax6 expression in Müller stem cells

  2008cites this paper
• Transmembrane proteins of tight junctions.

  2008cites this paper
• Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy

  2008cites this paper
• World Journal of Stem Cells

  year unknowncites this paper