Opioid μ‐receptors in the rostral medullary raphe modulate hypoxia‐induced hyperpnea in unanesthetized rats

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Acta Physiologica

• Publication date

  2012-03-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1111/j.1748-1716.2011.02345.xPMID 21827637
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• PreBötzinger Complex Neurokinin-1 Receptor-Expressing Neurons Mediate Opioid-Induced Respiratory Depression

  2011cited by this paper
• Ionotropic glutamatergic receptors in the rostral medullary raphe modulate hypoxia and hypercapnia-induced hyperpnea.

  2011cited by this paper
• Role of locus coeruleus noradrenergic neurons in cardiorespiratory and thermal control during hypoxia.

  2010cited by this paper
• Clinically relevant infusion rates of mu-opioid agonist remifentanil cause bradypnea in decerebrate dogs but not via direct effects in the pre-Bötzinger complex region.

  2010cited by this paper
• Central chemoreception is a complex system function that involves multiple brain stem sites.

  2009cited by this paper
• Micro-opioid receptor agonist injections into the presumed pre-Botzinger complex and the surrounding region of awake goats do not alter eupneic breathing.

  2009cited by this paper
• Role of preoptic opioid receptors in the body temperature reduction during hypoxia.

  2009cited by this paper
• Opioid mu-receptors in medullary raphe region affect the hypoxic ventilation in anesthetized rats.

  2009influential reference
• Activation of opioid micro-receptors in medullary raphe depresses sighs.

  2009influential reference
• 5‐HT1A, but not 5‐HT2 and 5‐HT7, receptors in the nucleus raphe magnus modulate hypoxia‐induced hyperpnoea

  2008cited by this paper
• Focal CO2 dialysis in raphe obscurus does not stimulate ventilation but enhances the response to focal CO2 dialysis in the retrotrapezoid nucleus.

  2008cited by this paper
• Activation of Opioid &mgr; Receptors in Caudal Medullary Raphe Region Inhibits the Ventilatory Response to Hypercapnia in Anesthetized Rats

  2007cited by this paper
• Serotoninergic receptors in the anteroventral preoptic region modulates the hypoxic ventilatory response

  2006cited by this paper
• A Novel Molecule with Peripheral Opioid Properties: The Effects on Hypercarbic and Hypoxic Ventilation at Steady-State Compared with Morphine and Placebo

  2006cited by this paper
• Involvement of serotoninergic receptors in the anteroventral preoptic region on hypoxia-induced hypothermia.

  2005cited by this paper
• Hypoxic activation of arterial chemoreceptors inhibits sympathetic outflow to brown adipose tissue in rats

  2005cited by this paper
• Both kappa and mu opioid agonists inhibit glutamatergic input to ventral tegmental area neurons.

  2005cited by this paper
• Hypocapnia decreases the amount of rapid eye movement sleep in cats.

  2004cited by this paper
• Opioid modulation of GABA release in the rat inferior colliculus

  2004cited by this paper
• Nitric oxide pathway in the nucleus raphe magnus modulates hypoxic ventilatory response but not anapyrexia in rats.

  2004cited by this paper
• Pharmacodynamic Effect of Morphine-6-glucuronide versus Morphine on Hypoxic and Hypercapnic Breathing in Healthy Volunteers

  2003cited by this paper
• Mu-opioid receptor agonist effects on medullary respiratory neurons in the cat: evidence for involvement in certain types of ventilatory disturbances.

  2003cited by this paper
• The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor*

  2003cited by this paper
• Hypocapnia decreases the amount of rapid eye movement sleep in cats.

  2003cited by this paper
• The nucleus raphe magnus modulates hypoxia-induced hyperventilation but not anapyrexia in rats.

  2003cited by this paper
• Hypoxia-induced anapyrexia: implications and putative mediators.

  2002cited by this paper
• Effects of intrathecal morphine on the ventilatory response to hypoxia.

  2000cited by this paper
• Cortical activation states in sleep and anesthesia. II: respiratory reflexes.

  1998cited by this paper
• Immunohistochemical localization of mu-opioid receptors in the central nervous system of the rat.

  1996cited by this paper
• Endogenous opioid modulation of hypercapnic-stimulated respiration in the rat.

  1994cited by this paper
• Potential adaptations to acute hypoxia: Hct, stress proteins, and set point for temperature regulation.

  1994cited by this paper
• Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: An in situ hybridization study

  1994cited by this paper
• Ventilatory and metabolic responses to cold and CO2 in intact and carotid body-denervated awake rats.

  1993cited by this paper
• Ventilatory and metabolic responses to cold and hypoxia in intact and carotid body-denervated rats.

  1992cited by this paper
• Opioid receptors and endogenous opioid peptides

  1991cited by this paper
• Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depression.

  1990cited by this paper
• Opioids and respiration.

  1989cited by this paper
• Opioids and breathing.

  1985cited by this paper
• Naloxone does not affect ventilatory responses to hypoxia and hypercapnia in rats.

  1984influential reference
• Anesthesia and Stimulation of Pituitary β-Endorphin Release in Rats

  1984cited by this paper
• Classification of opioid receptors.

  1983cited by this paper
• The rat brain in stereotaxic coordinates: Authors: George Paxinos & Charles Watson Academic Press Australia, 1982 Softback, 154 pages (including 71 plates), 35.00 Aust $

  1983influential reference
• EFFECTS OF URETHANE‐CHLORALOSE ANAESTHESIA ON RESPIRATION IN THE RAT

  1982cited by this paper
• Naloxone enhances respiratory output in cats.

  1979cited by this paper
• Effects of morphine on ventilatory response to exercise.

  1979cited by this paper
• Opiate analgesics inhibit substance P release from rat trigeminal nucleus

  1977cited by this paper
• Principles of comparative respiratory physiology

  1976cited by this paper
• Effect of meperidine on occlusion pressure responses to hypercapnia and hypoxia with and without external inspiratory resistance.

  1976cited by this paper
• Diminished ventilatory response to hypoxia and hypercapnia after morphine in normal man.

  1975cited by this paper
• Ventilation measured by body plethysmography in hibernating mammals and in poikilotherms.

  1973cited by this paper
• Control of breathing in experimental anemia.

  1970cited by this paper
• Effects of morphine and meperidine on the central respiratory mechanisms in the cat; the action of levallorphan in antagonizing these effects.

  1961cited by this paper
• On Cats

  1890cited by this paper
• IMMUNOHISTOCHEMICAL LOCALIZATION OF THE MU OPIOID RECEPTORS

  year unknowncited by this paper

• Opioid-induced respiratory depression: clinical aspects and pathophysiology of the respiratory network effects.

  2024cites this paper
• Contribution of the caudal medullary raphe to opioid induced respiratory depression.

  2022cites this paper
• Modulation of Cough Reflex by Gaba-Ergic Inhibition in Medullary Raphé of the Cat.

  2020cites this paper
• Systemic Oxygen Transport with Rest, Exercise, and Hypoxia: A Comparison of Humans, Rats, and Mice.

  2018cites this paper
• A Subregion of the Parabrachial Nucleus Partially Mediates Respiratory Rate Depression from Intravenous Remifentanil in Young and Adult Rabbits

  2017cites this paper
• The exocytotic machinery

  2014cites this paper
• Control of coughing by medullary raphé.

  2014cites this paper
• CrossTalk opposing view: The pre‐Bötzinger complex is not essential for respiratory depression following systemic administration of opioid analgesics

  2014cites this paper
• Participation of the dorsal periaqueductal grey matter in the hypoxic ventilatory response in unanaesthetized rats

  2014cites this paper
• Endogenous opiates and behavior: 2012.

  2013cites this paper
• Control and sensation of breathing during cycling exercise in hypoxia under naloxone: a randomised controlled crossover trial

  2013cites this paper
• Remifentanil reversibly abolished phrenic long term facilitation in rats subjected to acute intermittent hypoxia.

  2013cites this paper
• Opioid-senstive brainstem neurons seperately modulate pain and respiration

  2012cites this paper
• Pain-facilitating medullary neurons contribute to opioid-induced respiratory depression.

  2012cites this paper