Preliminary X-ray diffraction and ligand-binding analyses of the N-terminal domain of hypothetical protein Rv1421 from Mycobacterium tuberculosis H37Rv

A crystal of the N-terminal domain of hypothetical protein Rv1421 from Mycobacterium tuberculosis H37Rv (MtRv1421-NTD) diffracted to 1.7 Å resolution. MtRv1421-NTD, which contains a Walker A/B-like motif, can bind uridine diphosphate (UDP) and UDP-N-acetylglucosamine, indicating that the presence of a UDP moiety on the ligand may be essential for its interaction.

• Publication year

  2024

• Venue

  Acta Crystallographica Section F Structural Biology Communications

• Publication date

  2024-06-27

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1107/S2053230X24005831PMID 38935514PMCID 11229554
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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