Protracted Course of Staphylococcus lugdunensis Septic Arthritis in Native Knee Joint

Staphylococcus lugdunensis is a coagulase-negative bacteria of the Staphylococcus family. It is a highly invasive organism with similar virulence to Staphylococcus aureus. It is commonly associated with bacteremia and infections of the skin, soft tissues, joints, and bones. Those with indwelling medical devices are at the highest risk of infection due to biofilm formation. Instances of native joint infections are exceedingly rare. We describe a case of a 72-year-old female with multiple comorbidities presenting with native right knee joint septic arthritis from S. lugdunensis. Due to treatment noncompliance secondary to latent social determinants of health, she faced a complicated and protracted clinical course that was treated with inpatient intravenous antibiotics and outpatient oral doxycycline. Few cases of native joint infections with S. lugdunensis have been documented, and to our knowledge, the impact of treatment noncompliance on the sequelae of septic arthritis with this organism has not been reported. Socioeconomic factors and comorbidities have been shown to increase a patient’s risk for an extended joint infection with S. lugdunensis.

• Publication year

  2024

• Venue

  Cureus

• Publication date

  2024-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.7759/cureus.66848PMID 39280560PMCID 11395931
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bloodstream Infection Due to Coagulase-Negative Staphylococci: Impact of Species on Prevalence of Infective Endocarditis

  2023influential reference
• Characteristics and outcomes in adult patients with Staphylococcus lugdunensis bacteremia compared to patients with Staphylococcus epidermidis and Staphylococcus aureus bacteremia: a retrospective study in a 16-year period at the university hospital, Japan

  2023cited by this paper
• High-Grade Staphylococcus lugdunensis Bacteremia in a Patient on Home Hemodialysis.

  2023cited by this paper
• The Impact of Social Determinants of Health on Medication Adherence: a Systematic Review and Meta-analysis

  2021cited by this paper
• Staphylococcus lugdunensis Septic Arthritis following Arthroscopic Anterior Cruciate Ligament Reconstruction

  2020cited by this paper
• Staphylococcus lugdunensis: a Skin Commensal with Invasive Pathogenic Potential

  2020cited by this paper
• Staphylococcus lugdunensis: Review of Epidemiology, Complications, and Treatment

  2020cited by this paper
• Septic arthritis of native hip joint by Staphylococcus lugdunensis: a case report.

  2018cited by this paper
• Poverty, Transportation Access, and Medication Nonadherence

  2018cited by this paper
• S. lugdunensis Native-Joint Septic Arthritis: Case Report and Review of the Literature

  2017cited by this paper
• Staphylococcus lugdunensis Septic Arthritis of a Native Knee A Case Report.

  2016cited by this paper
• Staphylococcus lugdunensis septic arthritis and epidural abscess in a patient with rheumatoid arthritis receiving anti-tumour necrosis factor therapy.

  2014cited by this paper
• Staphylococcus lugdunensis: the coagulase-negative staphylococcus you don’t want to ignore

  2011cited by this paper
• Septic arthritis due to Staphylococcus lugdunensis in a native joint

  2010cited by this paper
• [Septic arthritis caused by Staphylococcus lugdunensis].

  2009cited by this paper
• From Clinical Microbiology to Infection Pathogenesis: How Daring To Be Different Works for Staphylococcus lugdunensis

  2008cited by this paper
• Development of antimicrobial resistance in Staphylococcus lugdunensis during treatment-report of a case of bacterial arthritis, vertebral osteomyelitis and infective endocarditis.

  2000cited by this paper

• No citing papers are available for this paper.