Introduction In March 2023, a Marburg Virus Disease (MVD) outbreak was declared in Kagera region, Northwestern Tanzania. This was the first MVD outbreak in the country. We describe the epidemiological characteristics of MVD cases and contacts. Methods The Ministry of Health activated an outbreak response team. Outbreak investigation methods were applied to cases identified through MVD standard case definitions and confirmed through reverse-transcriptase polymerase chain reaction (RT PCR). All identified case contacts were added into the contact listing form and followed up in-person daily for any signs or symptoms for 21 days. Data collected from various forms was managed and analyzed using Excel and QGIS software for mapping. Results A total of nine MVD cases were reported with eight laboratory-confirmed and one probable. Two of the reported cases were frontline healthcare workers and seven were family related members. Cases were children and adults between 1–59 years of age with a median age of 34 years. Six were males. Six cases died equivalent to a case fatality rate (CFR) of 66.7%. A total of 212 individuals were identified as contacts and two (2) became cases. The outbreak was localized in two geo-administrative wards (Maruku and Kanyangereko) of Bukoba District Council. Conclusion Transmission during this outbreak occurred among family members and healthcare workers who provided care to the cases. The delay in detection aggravated the spread and possibly the consequent fatality but once confirmed the swift response stemmed further transmission containing the disease at the epicenter wards. The outbreak lasted for 72 days but as the origin is still unknown, further research is required to explore the source of this outbreak.
Epidemiological description of Marburg virus disease outbreak in Kagera region, Northwestern Tanzania
Vida Mmbaga,George Mrema,Danstan Ngenzi,Welema Magoge,Emmanuel Mwakapasa,Frank Jacob,H. Matimba,Medard Beyanga,Angela Samweli,Michael Kiremeji,M. Kitambi,Erasto Sylvanus,Ernest Kyungu,Gerald Manase,Joseph Hokororo,Christer Kanyankole,Martin Rwabilimbo,Issessanda Kaniki,G. Kauki,M. E. Kelly,William Mwengee,Gabriel Ayeni,Faraja Msemwa,G. Saguti,George S. Mgomella,Kokuhabwa Mukurasi,Marcelina Mponela,E. Kapyolo,Jonathan Mcharo,Mary T Mayige,W. Gatei,I. Conteh,P. Mala,Maheshi Swaminathan,P. Horumpende,Paschal Ruggajo,G. Magembe,Z. Yoti,E. Kwesi,Tumaini Nagu
Published 2024 in PLoS ONE
ABSTRACT
PUBLICATION RECORD
- Publication year
2024
- Venue
PLoS ONE
- Publication date
2024-09-05
- Fields of study
Medicine, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
CITATION MAP
EXTRACTION MAP
CLAIMS
- No claims are published for this paper.
CONCEPTS
- No concepts are published for this paper.
REFERENCES
Showing 1-22 of 22 references · Page 1 of 1
CITED BY
Showing 1-15 of 15 citing papers · Page 1 of 1