Structural domains of interleukin-2 receptor beta critical for signal transduction: kinase association and nuclear complex-formation.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Biochemical Journal

• Publication date

  1995-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ3060217PMID 7532397PMCID PMC1136504
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2

  1994cited by this paper
• Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells

  1994cited by this paper
• Association of transcription factor APRF and protein kinase Jak1 with the interleukin-6 signal transducer gp130.

  1994cited by this paper
• Multiple tyrosine protein kinases in rat hippocampal neurons: isolation of Ptk-3, a receptor expressed in proliferative zones of the developing brain.

  1994cited by this paper
• Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components.

  1994cited by this paper
• Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes.

  1994cited by this paper
• Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors.

  1994cited by this paper
• Activation of receptor-associated tyrosine kinase JAK2 by prolactin.

  1994cited by this paper
• Identification of interleukin-2 receptor-associated tyrosine kinase p116 as novel leukocyte-specific Janus kinase.

  1994cited by this paper
• Mutational analysis of the intracellular domain of the human growth hormone receptor.

  1993cited by this paper
• Interferon-induced nuclear signalling by Jak protein tyrosine kinases

  1993cited by this paper
• Tyrosine phosphorylation of DNA binding proteins by multiple cytokines.

  1993cited by this paper
• Interleukin-2 induces tyrosine phosphorylation of the vav proto-oncogene product in human T cells: lack of requirement for the tyrosine kinase lck.

  1993cited by this paper
• Protein tyrosine kinases couple the interleukin‐2 receptor to p21ras

  1993cited by this paper
• Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte colony-stimulating factor receptor.

  1993cited by this paper
• Novel protein kinases expressed in human breast cancer

  1993cited by this paper
• Association of p56lck with IL‐2 receptor beta chain is critical for the IL‐2‐induced activation of p56lck.

  1993cited by this paper
• Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit.

  1993cited by this paper
• The proline-rich motif (PRM): a novel feature of the cytokine/hematopoietin receptor superfamily.

  1993cited by this paper
• Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4.

  1993cited by this paper
• Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.

  1993cited by this paper
• Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor.

  1993cited by this paper
• Signal transduction by the high‐affinity GM‐CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling.

  1993cited by this paper
• Human interleukin‐4 receptor signaling requires sequences contained within two cytoplasmic regions

  1993cited by this paper
• The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction.

  1993cited by this paper
• Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line.

  1993cited by this paper
• Inactivation of erythropoietin receptor function by point mutations in a region having homology with other cytokine receptors

  1993cited by this paper
• JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin.

  1993cited by this paper
• Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

  1993cited by this paper
• Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase.

  1993cited by this paper
• Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins

  1993cited by this paper
• Cloning of the gamma chain of the human IL-2 receptor.

  1992cited by this paper
• T-lymphocyte proliferation: tyrosine kinases in interleukin 2 signal transduction.

  1992cited by this paper
• Interleukin-2 (IL-2) induces tyrosine kinase-dependent translocation of active raf-1 from the IL-2 receptor into the cytosol.

  1992cited by this paper
• itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2.

  1992cited by this paper
• Interleukin 2 regulates the activity of the lyn protein-tyrosine kinase in a B-cell line.

  1992cited by this paper
• Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor.

  1992cited by this paper
• Interleukin (IL)-2 and IL-3 induce distinct but overlapping responses in murine IL-3-dependent 32D cells transduced with human IL-2 receptor beta chain: involvement of tyrosine kinase(s) other than p56lck.

  1992cited by this paper
• Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells.

  1992cited by this paper
• Characterization of a tyrosine kinase activity associated with the high-affinity interleukin 2 receptor complex.

  1992cited by this paper
• Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

  1991cited by this paper
• Transmembrane signalling by interleukin 2.

  1991cited by this paper
• A tyrosine kinase physically associates with the beta-subunit of the human IL-2 receptor.

  1991cited by this paper
• Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.

  1991cited by this paper
• Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.

  1991cited by this paper
• A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization.

  1989cited by this paper
• Two-dimensional analysis of interleukin 2-regulated tyrosine kinase activation mediated by the p70-75 beta subunit of the interleukin 2 receptor.

  1989cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• rapamycin survival and acts synergistically with cyclosporine but additively with Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft

  2013cites this paper
• to migrate CXCR3 and CXCR5 expressing lymphocytes and immature dendritic cells Autoantigens signal through chemokine receptors: uveitis antigens induce

  2013cites this paper
• Protein Phosphatase 2A Regulates Interleukin-2 Receptor Complex Formation and JAK3/STAT5 Activation*

  2009cites this paper
• Identification of a novel G245R polymorphism in the IL-2 receptor β membrane proximal domain associated with human visceral leishmaniasis

  2007cites this paper
• Activation of mitogen-activated protein kinase kinase (MEK)/extracellular signal regulated kinase (ERK) signaling pathway is involved in myeloid lineage commitment.

  2007cites this paper
• The Mannich Base NC1153 Promotes Long-Term Allograft Survival and Spares the Recipient from Multiple Toxicities1

  2005cites this paper
• Variants of CCR5, which are permissive for HIV-1 infection, show distinct functional responses to CCL3, CCL4 and CCL5

  2005cites this paper
• Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.

  2005cites this paper
• Identification of the Binding Domain of Signal-Transduction-Related Proteins on c-Mpl

  2003cites this paper
• Alternate signalling pathways from the interleukin-2 receptor.

  2002cites this paper
• Signaling through the Jak-Stat pathway: Regulation of tyrosine kinase activity

  2002cites this paper
• Histidyl–tRNA Synthetase and Asparaginyl–tRNA Synthetase, Autoantigens in Myositis, Activate Chemokine Receptors on T Lymphocytes and Immature Dendritic Cells

  2002cites this paper
• The role of parallel signaling pathways in maintaining lymphoid cell survival

  2002cites this paper
• Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.

  2002cites this paper
• Naturally Occurring CCR5 Extracellular and Transmembrane Domain Variants Affect HIV-1 Co-receptor and Ligand Binding Function*

  1999cites this paper
• JAK3, STAT, and MAPK signaling pathways as novel molecular targets for the tyrphostin AG-490 regulation of IL-2-mediated T cell response.

  1999cites this paper
• Inhibition of in vitro and in vivo HIV replication by a distamycin analogue that interferes with chemokine receptor function: a candidate for chemotherapeutic and microbicidal application.

  1998cites this paper
• Monocyte Chemotactic Protein-2 Activates CCR5 and Blocks CD4/CCR5-mediated HIV-1 Entry/Replication*

  1998cites this paper
• Small molecule inhibitor of HIV‐1 cell fusion blocks chemokine receptor‐mediated function

  1998cites this paper
• Mechanisms of cytokine signal transduction: IL-2, IL-4 and prolactin as hematopoietin receptor models.

  1998cites this paper
• Nitric oxide and thiol redox regulation of Janus kinase activity.

  1998cites this paper
• Cytokine Signaling and Mitogenic Responsiveness of B Cell Precursor Acute Lymphoblastic Leukemia

  1998cites this paper
• Two Discrete Regions of Interleukin-2 (IL2) Receptor β Independently Mediate IL2 Activation of a PD98059/Rapamycin/Wortmannin-insensitive Stat5a/b Serine Kinase*

  1997cites this paper
• Role of Kinases in HTLV-I Transformation

  1996cites this paper
• Excitatory sodium currents of NH15-CA2 neuroblastoma x glioma hybrid cells are differently affected by interleukin-2 and interleukin-1β

  1996cites this paper
• Activation of JAK3, but not JAK1, is critical for IL-2-induced proliferation and STAT5 recruitment by a COOH-terminal region of the IL-2 receptor beta-chain.

  1995cites this paper