Transport of β-amyloid from brain to eye causes retinal degeneration in Alzheimer’s disease

Qiuchen Cao,Shige Yang,Xiaowei Wang,Huaiqing Sun,Weijie Chen,Yuliang Wang,Junying Gao,Yanchi Wu,Qiuhua Yang,Xue Chen,Songtao Yuan,Ming Xiao,M. Nedergaard,Yuqing Huo,Qinghuai Liu

Published 2024 in Journal of Experimental Medicine

ABSTRACT

The article identifies a direct connection between the brain and the eyes where Aβ from the brain can be transported to the eyes via the brain–eye pathway, leading to Alzheimer’s disease retinopathy.

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