Modified ganglioside as a possible modulator of transmembrane signaling mechanism through growth factor receptors: a preliminary note.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1987-08-31

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0006-291X(87)80096-7PMID 3498483
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of protein kinase C activity by gangliosides.

  1987cited by this paper
• Lysosphingolipids inhibit protein kinase C: implications for the sphingolipidoses.

  1987cited by this paper
• Ganglioside-modulated protein phosphorylation in myelin.

  1987cited by this paper
• Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.

  1986cited by this paper
• Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

  1986cited by this paper
• Synthesis of lysogangliosides.

  1985cited by this paper
• Effect of Triton X-100 on insulin and epidermal growth factor receptor binding and autophosphorylation in Golgi fractions and partially purified receptors from rat liver.

  1985cited by this paper
• Preparation of GM1 ganglioside molecular species having homogeneous fatty acid and long chain base moieties.

  1985cited by this paper
• Ganglioside-mediated modulation of cell growth, growth factor binding, and receptor phosphorylation.

  1984cited by this paper
• Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes.

  1983cited by this paper
• GM3 ganglioside induces hamster fibroblast growth inhibition in chemically-defined medium: ganglioside may regulate growth factor receptor function.

  1982cited by this paper
• Simple micro-method for the isolation of gangliosides by reversed-phase chromatography

  1981cited by this paper
• Detection of phosphotyrosine-containing 34,000-dalton protein in the framework of cells transformed with Rous sarcoma virus.

  1981cited by this paper
• Glycosphingolipids in cellular interaction, differentiation, and oncogenesis.

  1981cited by this paper
• Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431.

  1978cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Preparation of lysohematoside from hematoside of equine erythrocyte and its chemical and hemolytic properties.

  1970cited by this paper
• IMMUNOCHEMICAL STUDIES OF LIPIDS. I. PREPARATION AND IMMUNOLOGICAL PROPERTIES OF SYNTHETIC PSYCHOSINE-PROTEIN ANTIGENS.

  1963cited by this paper
• CHROMATOGRAPHlC SEPARATION OF HUMAN BRAIN GANGLIOSIDES *

  1963cited by this paper
• Isolation of brain strandin, a new type of large molecule tissue component.

  1951cited by this paper

• Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute.

  2018cites this paper
• Hypothesis: Hypoxia induces de novo synthesis of NeuGc gangliosides in humans through CMAH domain substitute

  2017cites this paper
• Regulation of Growth Factor Receptors by Glycosphingolipids

  2016cites this paper
• GM3 and cancer

  2015cites this paper
• An Antibody to De-N-Acetyl Sialic Acid Containing-Polysialic Acid Identifies an Intracellular Antigen and Induces Apoptosis in Human Cancer Cell Lines

  2011cites this paper
• Ganglioside GM 3 Inhibits the Proliferation ot Cultured Keratinocytes

  2010cites this paper
• Lyso-GM3, its dimer, and multimer: their synthesis, and their effect on epidermal growth factor-induced receptor tyrosine kinase

  2007cites this paper
• Modification of pyrimidine derivatives from antiviral agents to antitumor agents.

  2006cites this paper
• Exogenous Ganglioside GD1a Enhances Epidermal Growth Factor Receptor Binding and Dimerization*

  2004cites this paper
• Benzamides and benzamidines as specific inhibitors of epidermal growth factor receptor and v-Src protein tyrosine kinases.

  2004cites this paper
• Regulation of Growth Factor Receptors by Gangliosides

  2002cites this paper
• Characterization of the reversible nature of the reaction catalyzed by sphingolipid ceramide N-deacylase. A novel form of reverse hydrolysis reaction.

  2001cites this paper
• Sporostatin, a novel and specific inhibitor of EGF receptor kinase.

  1999cites this paper
• Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A431.

  1999cites this paper
• Line , A 431 Factor Receptor Activity in an Epidermoid Carcinoma Cell Sialidase Gene Transfection Enhances Epidermal Growth

  1998cites this paper
• Growth Factor Receptors as Targets for Therapy in Pediatric Brain Tumors

  1998cites this paper
• Functional Roles of Glycosphingolipids and Sphingolipids in Signal Transduction

  1997cites this paper
• A Paradigm Case for the Merging of Glycal and Enzymatic Assembly Methods in Glycoconjugate Synthesis: A Highly Efficient Chemo‐Enzymatic Synthesis of GM3

  1996cites this paper
• GM2 ganglioside and pyramidal neuron dendritogenesis

  1995cites this paper
• Formation of lyso-glycosphingolipids by Streptomyces sp.

  1995cites this paper
• Sphingosine inhibits the synthesis of RNA primers by primase in vitro.

  1994cites this paper
• Total synthesis of a modified ganglioside, de-N-acetyl GM2.

  1994cites this paper
• Sphingolipid breakdown products: anti-proliferative and tumor-suppressor lipids.

  1993cites this paper
• Variable subcellular localization of glycosphingolipids.

  1993cites this paper
• TRENDS IN GLYCOSPHINGOLIPIDS CHANGE DURING GROWTH AND DIFFERENTIATION OF RAT RENAL GLOMERULAR EPITHELIAL CELLS, SGE1, IN VITRO

  1993cites this paper
• Ganglioside GM3 inhibits the proliferation of cultured keratinocytes.

  1993cites this paper
• Ceramide-mediated growth inhibition and CAPP are conserved in Saccharomyces cerevisiae.

  1993cites this paper
• Inhibition of tyrosylprotein sulfotransferase by sphingosine and its reversal by acidic phospholipids.

  1993cites this paper
• Exogenous gangliosides modulate calcium fluxes in cultured neuronal cells

  1992cites this paper
• Ganglioside composition and its relation to clinical data in brain tumors.

  1992cites this paper
• Tumor necrosis factor α stimulates sphingomyelinase through the 55 kDa receptor in HL‐60 cells

  1992cites this paper
• Total synthesis of the modified ganglioside de-N-acetyl-GM3 and some analogs.

  1992cites this paper
• Association of glycosphingolipids with intermediate filaments of mesenchymal, epithelial, glial, and muscle cells.

  1992cites this paper
• Gangliosides as modulators of cell function.

  1992cites this paper
• Tumor necrosis factor alpha stimulates sphingomyelinase through the 55 kDa receptor in HL-60 cells.

  1992cites this paper
• Sphingosine synergistically stimulates tumor necrosis factor alpha- induced prostaglandin E2 production in human fibroblasts

  1991cites this paper
• Cell regulation by sphingosine and more complex sphingolipids

  1991cites this paper
• Lipid modulators of epidermal proliferation and differentiation.

  1991cites this paper
• Apical and basal Forssman antigen in MDCK II cells: a morphological and quantitative study.

  1991cites this paper
• Murine Peritoneal Macrophage Gangliosides Inhibit Lymphocyte Proliferation

  1991cites this paper
• Galactocerebroside and sulfatide independently mediate Ca2+ responses in oligodendrocytes

  1991cites this paper
• Effects of gangliosides GM3 and De-N-acetyl GM3 on epidermal growth factor receptor kinase activity and cell growth.

  1991cites this paper
• Ligand-independent tyrosine phosphorylation of the receptor encoded by the c-neu oncogene.

  1991cites this paper
• Association of glycosphingolipids with intermediate filaments of human umbilical vein endothelial cells.

  1991cites this paper
• The role(s) of gangliosides in neural differentiation and repair: a perspective.

  1990cites this paper
• Density-dependent expression of ganglioside GM3 by human skin fibroblasts in an all-or-none fashion, as a possible modulator of cell growth in vitro.

  1990cites this paper
• A specific enhancing effect of N,N-dimethylsphingosine on epidermal growth factor receptor autophosphorylation. Demonstration of its endogenous occurrence (and the virtual absence of unsubstituted sphingosine) in human epidermoid carcinoma A431 cells.

  1990cites this paper
• Biosynthesis, Metabolism, and Biological Effects of Gangliosides

  1989cites this paper
• Differential inhibitory effects of TGF‐β on EGF‐, PDGF‐, and HBGF‐1‐stimulated MG63 human osteosarcoma cell growth: Possible involvement of growth factor interactions at the receptor and postreceptor levels

  1989cites this paper
• Enzymatic quantification of sphingosine in the picomole range in cultured cells.

  1989cites this paper
• Functions of sphingolipids and sphingolipid breakdown products in cellular regulation.

  1989cites this paper
• Synthesis and characterization of ganglioside GM3 derivatives: lyso-GM3, de-N-acetyl-GM3, and other compounds.

  1989cites this paper
• Early events in the antiproliferative action of tumor necrosis factor are similar to the early events in epidermal growth factor growth stimulation

  1989cites this paper
• Glycolipids and gliomas. A review.

  1988cites this paper
• Gangliosides in neuroblastomas.

  1988cites this paper
• Regulation of proliferation by the cholera toxin B subunit in FRTL-5 cells may involve a mechanism independent from the modulation of membrane receptor function.

  1988cites this paper
• Protein kinase C regulation by sphingosine/lysosphingolipids.

  1988cites this paper
• Gangliosides and energy substrates in brown adipose tissue of cold-acclimated rat.

  1988cites this paper
• A novel ganglioside, de-N-acetyl-GM3 (II3NeuNH2LacCer), acting as a strong promoter for epidermal growth factor receptor kinase and as a stimulator for cell growth.

  1988cites this paper
• Sialidase activities of cultured human fibroblasts and the metabolism of GM3 ganglioside.

  1988cites this paper
• Growth control of human foreskin fibroblasts and inhibition of extracellular sialidase activity by 2-deoxy-2,3-dehydro-N-acetylneuraminic acid.

  1988cites this paper
• Synthesis and characterization of lyso-GM3 (II3Neu5Ac Lactosyl sphingosine), de-N-acetyl-GM3 (II3NeuNH2 lactosyl Cer), and related compounds.

  1988cites this paper
• Activation of the epidermal growth factor receptor tyrosine protein kinase in the absence of receptor oligomerization.

  1988cites this paper
• Promotion of survival and neurite outgrowth of cultured peripheral neurons by exogenous lipids and detergents.

  1988cites this paper