透明质酸钠、皮质类固醇、自体富血小板血浆治疗原发性冻结肩的效果对比

目的 原发性冻结肩是一种严重影响患者生活质量的肩关节疾病，关节腔注射是治疗该疾病的常见方式。本研究旨在探究和比较透明质酸钠(sodium hyaluronate，SH)、皮质类固醇(corticosteroids，CS)、自体富血小板血浆(platelet-rich plasma，PRP)对原发性冻结肩的治疗效果。 方法 回顾性纳入2020年1月1日至2022年12月31日在中南大学湘雅三医院确诊为原发性冻结肩并在B超引导下进行盂肱关节单次注射SH、CS或PRP的117例患者，分为SH组、CS组和PRP组。收集治疗前和治疗1、3、6个月时患者的患肩疼痛视觉模拟量表(Visual Analogue Scale，VAS)评分、活动范围、Constant评分和上肢功能障碍(Disabilities of Arm, Shoulder, and Hand，DASH)评分等临床资料，比较这3种关节腔注射治疗方法对原发性冻结肩的疗效。 结果 与治疗前相比，SH组、CS组、PRP组在治疗6个月时均能改善肩关节VAS疼痛评分、活动范围、Constant评分和DASH评分(均P<0.05)。与SH组和PRP组相比，CS组在治疗1个月时的VAS疼痛评分、活动范围、Constant评分和DASH评分均更好(均P<0.05)，而PRP组在治疗6个月时的VAS疼痛评分、Constant评分和DASH评分均优于SH组和CS组(均P<0.05)。 结论 B超引导下盂肱关节单次注射SH、CS或PRP均能明显改善原发性冻结肩患者的疼痛程度、活动范围及关节功能。这3种注射治疗方法中，CS可能有更好的早期疗效，而PRP的长期疗效可能更好。

• Publication year

  2024

• Venue

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

• Publication date

  2024-08-28

• Fields of study

  Not labeled

• Identifiers
  DOI 10.11817/j.issn.1672-7347.2024.240219PMID 39788515PMCID 11628216
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Adhesive Capsulitis.

  2023cited by this paper
• Effect of proprioceptive neuromuscular facilitation technique on the treatment of frozen shoulder: a pilot randomized controlled trial

  2022cited by this paper
• Rehabilitative treatments in adhesive capsulitis: a systematic review.

  2022cited by this paper
• The Effect of Intra-articular Injection of Hyaluronic Acid in Frozen Shoulder: a Systematic Review and Meta-analysis of Randomized Controlled Trials

  2022cited by this paper
• Efficacy of platelet-rich plasma injections in patients with adhesive capsulitis of the shoulder

  2020cited by this paper
• Comparison of Treatments for Frozen Shoulder

  2020cited by this paper
• Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory

  2019cited by this paper
• Treatment of Adhesive Capsulitis of the Shoulder.

  2019cited by this paper
• The Effect of Corticosteroid Injection Into Rotator Interval for Early Frozen Shoulder: A Randomized Controlled Trial

  2018cited by this paper
• Shoulder adhesive capsulitis: epidemiology and predictors of surgery.

  2018cited by this paper
• Platelet-rich plasma and the shoulder: clinical indications and outcomes

  2018cited by this paper
• Rheological study of hyaluronic acid derivatives

  2017cited by this paper
• Comparative Efficacy of Platelet Rich Plasma Injection, Corticosteroid Injection and Ultrasonic Therapy in the Treatment of Periarthritis Shoulder.

  2017cited by this paper
• Platelet-Released Growth Factors Modulate the Secretion of Cytokines in Synoviocytes under Inflammatory Joint Disease

  2017cited by this paper
• The effect of intra-articular hyaluronate and tramadol injection on patients with adhesive capsulitis of the shoulder

  2017cited by this paper
• Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis

  2017cited by this paper
• Adhesive capsulitis of the shoulder, treatment with corticosteroid, corticosteroid with distension or treatment-as-usual; a randomised controlled trial in primary care

  2016cited by this paper
• Ultrasound-guided intra-articular and rotator interval corticosteroid injections in adhesive capsulitis of the shoulder: a double-blind, sham-controlled randomized study

  2015cited by this paper
• Frozen shoulder: A systematic review of therapeutic options.

  2015cited by this paper
• Conservative integrated treatment of adhesive capsulitis of the shoulder.

  2014cited by this paper
• The effectiveness of physiotherapeutic interventions in treatment of frozen shoulder/adhesive capsulitis: A systematic review

  2014cited by this paper
• Comparison of manipulation and arthroscopic capsular release for adhesive capsulitis: a systematic review.

  2013cited by this paper
• Platelet-rich plasma: a milieu of bioactive factors.

  2012cited by this paper
• Adhesive Capsulitis of the Shoulder

  2011cited by this paper
• Adhesive capsulitis: a review.

  2011cited by this paper
• Nonoperative management of adhesive capsulitis of the shoulder: oral cortisone application versus intra-articular cortisone injections.

  2010cited by this paper
• Frozen shoulder: the effectiveness of conservative and surgical interventions—systematic review

  2010cited by this paper
• Long-term outcome of frozen shoulder.

  2008cited by this paper
• The pathology of frozen shoulder.

  2007cited by this paper

• No citing papers are available for this paper.