Beyond the Microbiome: The Role of the Metabolome and Diet in Antitumor Immunity.

N. Dizman,M. Roberts,Jennifer McQuade

Published 2025 in European Urology Focus

ABSTRACT

Microbiome-derived or -modulated metabolites (short-chain fatty acids, bile acids, and amino acids) could mediate antitumor immunity. Diet offers an actionable route for manipulating both the microbiome and the metabolome. Diet- and microbiome-directed trials with robust translational correlates are eagerly awaited.

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