Sex‐dependent vascular effects of transient receptor potential (TRP) channels and sex dimorphism in migraine are not yet fully characterized. We investigated the differential vasoactive effects of TRP ankyrin 1 (TRPA1), TRP melastatin 3 (TRPM3) and TRP vanilloid 1 (TRPV1) channels, their pharmacological mechanism(s), and localization and expression in human isolated blood vessels.
Sex differences in the vasoactive effect of transient receptor potential channels: TRPM3 as a new therapeutic target for (neuro)vascular disorders
Eduardo Rivera-Mancilla,Usha M. Musterd-Bhaggoe,Dennis Schutter,Antoon J. van den Bogaerdt,Arnaud Vincent,Carlos M Villalón,A. Danser,A. Maassenvandenbrink
Published 2025 in British Journal of Pharmacology
ABSTRACT
PUBLICATION RECORD
- Publication year
2025
- Venue
British Journal of Pharmacology
- Publication date
2025-02-16
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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