Coagulation Factors and White Matter Hyperintensities in Middle‐Aged Women With and Without Migraine and Ischemic Stroke

Mariam Ali,N. Weerd,H. J. A. Os,Annelise E Wilms,Ghislaine Holswilder,Katie M. Linstra,Thijs W. Harten,S. Cannegieter,B. Siegerink,B. J. M. Vlijmen,L. Ruhaak,N. Kruyt,M. Kruit,A. Brink,G. Terwindt,M. Wermer

Published 2025 in European Journal of Neurology

ABSTRACT

Migraine increases the risk of ischemic stroke and white matter hyperintensities (WMH), especially in women. Underlying shared mechanisms may include endothelial activation and hypercoagulability. We assessed these markers in middle‐aged women with and without migraine and ischemic stroke to explore their role in WMH development.

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