Gastric Infusion of Short-Chain Fatty Acids Improves Health via Enhance Liver and Intestinal Immune Response and Antioxidant Capacity in Goats

Simple Summary The gastrointestinal tract digests, absorbs, and metabolizes dietary nutrients and is considered a major immune organ in the body, with more than 70% of its immune cells. Short-chain fatty acids, including acetate, propionate, and butyrate, account for more than 70% of 75% of energy sources and can increase feed intake and body weight of ruminants as well as have anti-inflammatory, antioxidant, and antimicrobial effects. In this study, gastric infusion of short-chain fatty acids (acetate, propionate, and butyrate) in goats increased antioxidant enzyme activity, anti-inflammatory cytokines, and intestinal tight-junction protein expression. These results may contribute to improving goat intestinal health and productivity by boosting antioxidant capacity and modulating cytokines, and pro-inflammatory and anti-inflammatory cytokines.

• Publication year

  2025

• Venue

  Veterinary Sciences

• Publication date

  2025-04-22

• Fields of study

  Agricultural and Food Sciences, Medicine

• Identifiers
  DOI 10.3390/vetsci12050395PMID 40431488PMCID 12115894
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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