Predicting Surfactant Need at Birth: Failed Validation of a Bedside Method Using Gastric Aspirates

C. Heiring,Porntiva Poorisrisak,N. Breindahl,G. Zachariassen,Maria-Christina Eckardt,A. Viuff,Lars Bender,Peter Agergaard,L. Aunsholt,Tine Brink Henriksen

Published 2025 in Acta paediatrica

ABSTRACT

To validate a prototype point‐of‐care (POC) test for the lecithin/sphingomyelin (L/S) ratio by identifying the optimal L/S cut‐off for predicting surfactant need in preterm infants < 30 weeks' gestation using gastric aspirates (GAS) sampled at birth and to assess clinical feasibility.

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