Implication for health policy/practice/research/medical education:Congo red negative nodular deposition of an amorphous, eosinophilic material is the most common pathologic finding in light chain deposition disease in light microscopy. The nodules are a mixture of light chain and mesangial protein and the picture is reminiscent of diabetic nephropathy. Immunoflurescent microscopy usually demonstrates the presence of monotypic kappa light chain. It seems that serum creatinine level greater than 4 mg/dl is a poor prognosis sign for future progress to end stage renal disease in this disease. Therefore, early diagnosis is important.
Light chain deposition disease; there are reasons for confusion
Published 2013 in Journal of Renal Injury Prevention
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- Publication year
2013
- Venue
Journal of Renal Injury Prevention
- Publication date
2013-10-10
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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