The Association of Insomnia with Febrile Neutropenia, Leucopenia, and Infection in Women Receiving Adjuvant Chemotherapy for Breast Cancer

Simple Summary Insomnia can affect the immune system. Cancer chemotherapy can also affect the immune system. This study evaluated whether there was an association between insomnia and immune dysfunction (neutropenia, leucopenia, and the occurrence of infections) in women treated with chemotherapy after breast cancer surgery. Insomnia was associated with febrile neutropenia, a serious consequence of immune dysfunction in patients receiving chemotherapy. This association remained significant after adjusting for confounders. In addition, chemotherapy dose reductions (often necessary to manage adverse effects) were more common in women with insomnia.

• Publication year

  2025

• Venue

  Cancers

• Publication date

  2025-05-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.3390/cancers17111838PMID 40507319PMCID 12153840
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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