Guanylyl cyclase signaling in AFD neurons regulates systemic stress resilience in Caenorhabditis elegans

No abstract is available for this paper.

• Publication year

  2025

• Venue

  bioRxiv

• Publication date

  2025-07-11

• Fields of study

  Biology, Environmental Science

• Identifiers
  DOI 10.1101/2025.07.08.663649
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• The Thermal Stress Coping Network of the Nematode Caenorhabditis elegans

  2022cited by this paper
• Temperature-Dependent Regulation of Proteostasis and Longevity

  2022cited by this paper
• The Caenorhabditis elegans 12‐kDa small heat shock proteins with little in vitro chaperone activity play crucial roles for its dauer formation, longevity, and reproduction

  2021cited by this paper
• Transcription factors and chaperone proteins play a role in launching a faster response to heat stress and aggregation

  2021cited by this paper
• Chaperone biomarkers of lifespan and penetrance track the dosages of many other proteins

  2019cited by this paper
• Caenorhabditis elegans Genes Affecting Interindividual Variation in Life-span Biomarker Gene Expression

  2017cited by this paper
• Genetic interaction with temperature is an important determinant of nematode longevity

  2017cited by this paper
• Receptor-type Guanylyl Cyclases Confer Thermosensory Responses in C. elegans.

  2016influential reference
• OASIS 2: online application for survival analysis 2 with features for the analysis of maximal lifespan and healthspan in aging research

  2016cited by this paper
• Using measures of single‐cell physiology and physiological state to understand organismic aging

  2015cited by this paper
• A first line of stress defense: small heat shock proteins and their function in protein homeostasis.

  2015cited by this paper
• Triggers the Heat Shock Response in C . elegans in the Absence of Temperature Increase

  2014cited by this paper
• Chaperone function and mechanism of small heat-shock proteins.

  2014cited by this paper
• Integrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1

  2014cited by this paper
• Ciliopathy proteins establish a bipartite signaling compartment in a C. elegans thermosensory neuron

  2014cited by this paper
• Predicting longevity in C. elegans: fertility, mobility and gene expression.

  2013cited by this paper
• XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity.

  2013cited by this paper
• A Neuronal GPCR is Critical for the Induction of the Heat Shock Response in the Nematode C. elegans

  2013cited by this paper
• GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis

  2013cited by this paper
• Small heat-shock proteins protect from heat-stroke-associated neurodegeneration

  2012cited by this paper
• Temperature- and Touch-Sensitive Neurons Couple CNG and TRPV Channel Activities to Control Heat Avoidance in Caenorhabditis elegans

  2012cited by this paper
• Expression of a single-copy hsp-16.2 reporter predicts life span.

  2012cited by this paper
• Fiji: an open-source platform for biological-image analysis

  2012cited by this paper
• The heat shock response: systems biology of proteotoxic stress in aging and disease.

  2011cited by this paper
• Longevity and stress in Caenorhabditis elegans

  2011cited by this paper
• Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins

  2011cited by this paper
• Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila.

  2010cited by this paper
• The heat shock response: life on the verge of death.

  2010cited by this paper
• Regulation of the Cellular Heat Shock Response in Caenorhabditis elegans by Thermosensory Neurons

  2008cited by this paper
• Bidirectional temperature-sensing by a single thermosensory neuron in C. elegans

  2008cited by this paper
• The sensory cilia of Caenorhabditis elegans.

  2007cited by this paper
• The AFD Sensory Neurons Encode Multiple Functions Underlying Thermotactic Behavior in Caenorhabditis elegans

  2006cited by this paper
• Identification of Guanylyl Cyclases That Function in Thermosensory Neurons of Caenorhabditis elegans

  2006influential reference
• A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans

  2005cited by this paper
• Neuronal substrates of complex behaviors in C. elegans.

  2005cited by this paper
• Tissue‐specific expression, heat inducibility, and biological roles of two hsp16 genes in Caenorhabditis elegans

  2003cited by this paper
• Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

  2003cited by this paper
• Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

  2003cited by this paper
• Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones.

  2003cited by this paper
• Association of several small heat-shock proteins with reproductive tissues in the nematode Caenorhabditis elegans.

  2000cited by this paper
• Functional reconstitution of a heteromeric cyclic nucleotide-gated channel of Caenorhabditis elegans in cultured cells.

  1999cited by this paper
• Genetics of chemotaxis and thermotaxis in the nematode Caenorhabditis elegans.

  1999cited by this paper
• Role of Heat Shock Proteins in Protection from and Pathogenesis of Infectious Diseases

  1999cited by this paper
• Thermal avoidance in Caenorhabditis elegans: an approach to the study of nociception.

  1999cited by this paper
• Direct observation of stress response in Caenorhabditis elegans using a reporter transgene.

  1999cited by this paper
• Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators.

  1998cited by this paper
• The heat-shock response: regulation and function of heat-shock proteins and molecular chaperones.

  1997cited by this paper
• Unique Structural Features of a Novel Class of Small Heat Shock Proteins*

  1997cited by this paper
• A putative cyclic nucleotide-gated channel is required for sensory development and function in C. elegans.

  1996cited by this paper
• Mutations in a cyclic nucleotide-gated channel lead to abnormal thermosensation and chemosensation in C. elegans.

  1996cited by this paper
• Thermotolerance of a long-lived mutant of Caenorhabditis elegans.

  1994cited by this paper
• [Genetics of Caenorhabditis elegans].

  1989cited by this paper
• The Caenorhabditis elegans hsp70 gene family: a molecular genetic characterization.

  1988cited by this paper
• Normal and mutant thermotaxis in the nematode Caenorhabditis elegans.

  1975cited by this paper

• No citing papers are available for this paper.