Linking pregnancy- and birth-related risk factors to a multivariate fusion of child cortical structure

Significance Early life stages, including pregnancy and birth circumstances, are critically important for a wide range of real-life outcomes for the child. In this study, we linked maternal complications during pregnancy and low birth weight and prematurity to globally reduced cortical surface area, and low birth weight and prematurity, in addition to pregnancy and birth complications, to complex cortical structural patterns later in late childhood. Our findings underscore the importance of providing support to mothers and children during these crucial phases, helping to ensure optimal conditions for healthy child development.

• Publication year

  2025

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2025-06-17

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1073/pnas.2422281122PMID 40526716PMCID 12207422
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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