Multiomics analysis reveals the genetic and epigenetic features of high-risk NK cell–type chronic active EBV infection

Key Points • We identified a high-risk subtype of NK cell–type CAEBV characterized by a high CpG island methylation pattern.• 5-Azacytidine is effective against this subtype of NK cell–type CAEBV in vitro and in vivo, suggesting it is a novel potential therapy.

• Publication year

  2025

• Venue

  Blood

• Publication date

  2025-07-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/blood.2024026805PMID 40737598PMCID 12824651
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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