Neurodevelopmental Vulnerability in Alzheimer's Disease and Frontotemporal Dementia

Neurodevelopmental disorders (NDDs) may influence the course of Alzheimer's disease (AD) and frontotemporal dementia (FTD). However, prior studies have focused on specific pairs of NDDs and variants of AD/FTD. Adopting a dimensional approach to NDDs and considering the heterogeneity of AD/FTD, we investigated the association between a neurodevelopmental vulnerability (DV) and the clinical presentation and age at onset of AD/FTD.

• Publication year

  2025

• Venue

  European Journal of Neurology

• Publication date

  2025-08-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/ene.70322PMID 40757649PMCID 12319707
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Dissociable spatial topography of cortical atrophy in early‐onset and late‐onset Alzheimer's disease: A head‐to‐head comparison of the LEADS and ADNI cohorts

  2025cited by this paper
• The High Rates of Comorbidity among Neurodevelopmental Disorders: Reconsidering the Clinical Utility of Distinct Diagnostic Categories

  2024cited by this paper
• Adult Attention Deficit-Hyperactivity Disorder is associated with Lewy Body Disease and Cognitive Impairment: A prospective cohort Study With 15-year Follow-Up.

  2024cited by this paper
• Factors Affecting Resilience and Prevention of Alzheimer's Disease and Related Dementias

  2024cited by this paper
• Clinical recognition of frontotemporal dementia with right anterior temporal predominance: A multicenter retrospective cohort study

  2024cited by this paper
• Can neurodevelopmental disorders influence the course of neurodegenerative diseases? A scoping review.

  2024cited by this paper
• Diagnosed Developmental Disabilities in Children Aged 3-17 Years: United States, 2019-2021.

  2023influential reference
• Timing of lifespan influences on brain and cognition.

  2023cited by this paper
• Suspected neurodevelopmental disorders in adult patients of memory clinics: Start at the beginning. GREDEV proposals for clinical practice.

  2022cited by this paper
• Investigation of the Association Between History of Learning Disabilities and Primary Progressive Aphasia in Brazilian Portuguese Speakers

  2022cited by this paper
• Current state of knowledge on the prevalence of neurodevelopmental disorders in childhood according to the DSM-5: a systematic review in accordance with the PRISMA criteria

  2022cited by this paper
• A framework for concepts of reserve and resilience in aging.

  2022cited by this paper
• Neurodevelopmental effects of genetic frontotemporal dementia in young adult mutation carriers.

  2022cited by this paper
• The relationship between executive function, neurodevelopmental disorder traits, and academic achievement in university students

  2022cited by this paper
• The World Federation of ADHD International Consensus Statement: 208 Evidence-based Conclusions about the Disorder.

  2021cited by this paper
• The prevalence and incidence of early‐onset dementia among adults with autism spectrum disorder

  2021cited by this paper
• Neurodevelopmental and Neurodegenerative Similarities and Interactions: A Point of View About Lifelong Neurocognitive Trajectories

  2021cited by this paper
• Attention‐deficit/hyperactivity disorder and Alzheimer's disease and any dementia: A multi‐generation cohort study in Sweden

  2021cited by this paper
• An Integrative Literature Review on the Nomenclature and Definition of Dementia at a Young Age

  2021cited by this paper
• Dementia prevention, intervention, and care: 2020 report of the Lancet Commission

  2020cited by this paper
• Exploring the causal effects of genetic liability to ADHD and Autism on Alzheimer’s disease

  2020cited by this paper
• Considering learning disabilities and attention-deficit hyperactivity disorder when assessing for neurodegenerative disease.

  2019cited by this paper
• Sex differences in neurodevelopmental disorders.

  2019cited by this paper
• Prevalence of Mathematical and Visuospatial Learning Disabilities in Patients With Posterior Cortical Atrophy

  2018cited by this paper
• Neurodevelopmental disorders.

  2017cited by this paper
• Imaging and rare APOE alleles

  2016cited by this paper
• Sex/Gender Differences and Autism: Setting the Scene for Future Research

  2015cited by this paper
• Normative data for the Rey-Osterrieth and the Taylor complex figure tests in Quebec-French people.

  2015cited by this paper
• Lifelong Reading Disorder and Mild Cognitive Impairment: Implications for Diagnosis

  2015cited by this paper
• Handbook of Cluster Analysis

  2015cited by this paper
• Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria.

  2014cited by this paper
• Association between the prevalence of learning disabilities and primary progressive aphasia.

  2014cited by this paper
• Developmental dyslexia in adults: behavioural manifestations and cognitive correlates.

  2014cited by this paper
• Primary progressive aphasia and the language network

  2013cited by this paper
• Neurodevelopmental disorders

  2013cited by this paper
• Handedness and language learning disability differentially distribute in progressive aphasia variants.

  2013cited by this paper
• La batterie d'évaluation des connaissances sémantiques du GRECO (BECS-GRECO) : validation et données normatives

  2011cited by this paper
• Classification of primary progressive aphasia and its variants

  2011cited by this paper
• Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.

  2011cited by this paper
• MatchIt: Nonparametric Preprocessing for Parametric Causal Inference

  2011cited by this paper
• The COSMIN checklist for assessing the methodological quality of studies on measurement properties of health status measurement instruments: an international Delphi study

  2010cited by this paper
• FactoMineR: An R Package for Multivariate Analysis

  2008cited by this paper
• Increased frequency of learning disability in patients with primary progressive aphasia and their first-degree relatives.

  2008cited by this paper
• The significance of dyslexia screening for the assessment of dementia in older people

  2008cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders

  2008cited by this paper
• Incidence and prevalence of dementia in elderly adults with mental retardation without down syndrome.

  2004cited by this paper
• Standardisation et étalonnage français du Mini Mental State (MMS) version GRÉCO

  2003cited by this paper
• The FAB: A frontal assessment battery at bedside

  2001cited by this paper
• The FAB: A frontal assessment battery at bedside

  2000cited by this paper

• Neurodevelopmental origins of age-related neurodegenerative diseases

  2026cites this paper
• The dopaminergic system in neurodevelopment: preclinical models of neurodevelopmental disorders and susceptibility to neurodegeneration

  2026cites this paper