Orthologous metabonomic qualification of a rodent model combined with magnetic resonance imaging for an integrated evaluation of the toxicity of Hypochoeris radicata.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Chemical Research in Toxicology

• Publication date

  2008-09-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1021/tx800159xPMID 18783252
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Stringhalt associated with a pasture infested with Hypochoeris radicata

  2010cited by this paper
• Alterations of striatal glutamate transmission in rotenone-treated mice: MRI/MRS in vivo studies.

  2008cited by this paper
• N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology.

  2007cited by this paper
• Effect of pH on 1H-NMR spectroscopy of mouse urine.

  2007cited by this paper
• Application of metabonomics in a comparative profiling study reveals N-acetylfelinine excretion as a biomarker for inhibition of the farnesyl pathway by bisphosphonates.

  2007cited by this paper
• Elevated brain scyllo‐inositol concentrations in patients with Alzheimer's disease

  2007cited by this paper
• Properties of scyllo–inositol as a therapeutic treatment of AD-like pathology

  2007cited by this paper
• Beyond blood sugar: the potential of NMR-based metabonomics for type 2 human diabetes, and the horse as a possible model

  2007cited by this paper
• Sexual dimorphism in liver mitochondrial oxidative capacity is conserved under caloric restriction conditions.

  2007cited by this paper
• The application of NMR-based metabonomics in neurological disorders

  2006cited by this paper
• Down‐regulation of vesicular glutamate transporters precedes cell loss and pathology in Alzheimer's disease

  2006cited by this paper
• Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

  2006cited by this paper
• Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

  2005cited by this paper
• High Resolution 1H NMR-based Metabolomics Indicates a Neurotransmitter Cycling Deficit in Cerebral Tissue from a Mouse Model of Batten Disease*

  2005cited by this paper
• The metabonomics of aging and development in the rat: an investigation into the effect of age on the profile of endogenous metabolites in the urine of male rats using 1H NMR and HPLC-TOF MS.

  2005cited by this paper
• Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics.

  2005cited by this paper
• Protective Mechanisms of Inosine in Platelet Activation and Cerebral Ischemic Damage

  2005cited by this paper
• Magnetic resonance spectroscopy in cognitive research.

  2004cited by this paper
• Studying rat brain neurochemistry using nanoprobe NMR spectroscopy: a metabonomics approach.

  2004cited by this paper
• Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification.

  2004cited by this paper
• Sex differences in the vulnerability to drug abuse: a review of preclinical studies.

  2004cited by this paper
• High cerebral scyllo-inositol: a new marker of brain metabolism disturbances induced by chronic alcoholism

  2004cited by this paper
• So what's the deal with metabonomics?

  2003cited by this paper
• Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

  2003cited by this paper
• N‐acetyl aspartate estimation: a potential method for determining neuronal loss in the transmissible spongiform encephalopathies

  2003cited by this paper
• NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats.

  2003cited by this paper
• Gliomatosis cerebri: clinical, neurochemical and neuroradiological response to temozolomide administration.

  2003cited by this paper
• Influence of dietary arginine on sexual dimorphism of arginine metabolism in mice.

  2003cited by this paper
• Widespread inosine‐containing mRNA in lymphocytes regulated by ADAR1 in response to inflammation

  2003cited by this paper
• NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate.

  2002cited by this paper
• Aberrant Expression of the Glutamate Transporter Excitatory Amino Acid Transporter 1 (EAAT1) in Alzheimer's Disease

  2002cited by this paper
• Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance

  2002cited by this paper
• Metabonomic assessment of physiological disruptions using 1H-13C HMBC-NMR spectroscopy combined with pattern recognition procedures performed on filtered variables.

  2002cited by this paper
• Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

  2002cited by this paper
• Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS‐DA

  2002cited by this paper
• Choline is increased in pre-lesional normal appearing white matter in multiple sclerosis

  2002cited by this paper
• Inositol monophosphatase activity in normal, Down syndrome and dementia of the Alzheimer type CSF.

  2002cited by this paper
• Metabonomics: a platform for studying drug toxicity and gene function

  2002cited by this paper
• Glutamate uptake.

  2001cited by this paper
• Magnetic resonance spectroscopy of the human brain

  2001cited by this paper
• Accumulation of N‐Acetyl‐L‐Aspartate in the Brain of the Tremor Rat, a Mutant Exhibiting Absence‐Like Seizure and Spongiform Degeneration in the Central Nervous System

  2000cited by this paper
• An NMR‐based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

  2000cited by this paper
• 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data.

  1999cited by this paper
• Effects of myo-inositol ingestion on human brain myo-inositol levels: a proton magnetic resonance spectroscopic imaging study.

  1999cited by this paper
• Toward an in vivo neurochemical profile: quantification of 18 metabolites in short-echo-time (1)H NMR spectra of the rat brain.

  1999cited by this paper
• In Vivo 1 H NMR Spectroscopy of Rat Brain at 1 ms

  1999cited by this paper
• Inosine and guanosine preserve neuronal and glial cell viability in mouse spinal cord cultures during chemical hypoxia.

  1999cited by this paper
• In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time

  1999cited by this paper
• Effect of diet on the urinary excretion of hippuric acid and other dietary-derived aromatics in rat. A complex interaction between diet, gut microflora and substrate specificity.

  1998cited by this paper
• Brain biochemistry in Duchenne muscular dystrophy: a 1H magnetic resonance and neuropsychological study.

  1998cited by this paper
• Outbreaks of stringhalt in southern Chile

  1998cited by this paper
• Proton‐Decoupled 31P Magnetic Resonance Spectroscopy Reveals Osmotic and Metabolic Disturbances in Human Hepatic Encephalopathy

  1998cited by this paper
• Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder.

  1997cited by this paper
• Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease.

  1996cited by this paper
• Regional gray and white matter metabolite differences in subjects with AD, with subcortical ischemic vascular dementia, and elderly controls with 1H magnetic resonance spectroscopic imaging.

  1996cited by this paper
• Natural course of diabetic peripheral neuropathy in spontaneous-onset diabetic Chinese hamsters.

  1995cited by this paper
• Proton MRS of Gadolinium‐enhancing MS Plaques and Metabolic Changes in Normal‐Appearing White Matter

  1995cited by this paper
• Serial proton magnetic resonance spectroscopy in acute multiple sclerosis lesions.

  1994cited by this paper
• Hypochoeris-associated stringhalt in North America.

  1993cited by this paper
• The proton NMR spectrum in acute EAE: The significance of the change in the Cho:Cr ratio

  1993cited by this paper
• Pathological aspects of Australian Stringhalt.

  1992cited by this paper
• Stringhalt--current thoughts on aetiology and pathogenesis.

  1992cited by this paper
• LOCALIZED H-1-NMR SPECTROSCOPY IN CANAVANS DISEASE - A REPORT OF 2 CASES

  1991cited by this paper
• Localized 1H NMR spectroscopy in Canavan's Disease: A report of two cases

  1991cited by this paper
• Phospholipases in biology and medicine.

  1990cited by this paper
• In vivo assessment of N-acetylaspartate in brain in spongy degeneration (Canavan's disease) by proton spectroscopy.

  1990cited by this paper
• Methylamine and polyol responses to salt loading in renal inner medulla.

  1989cited by this paper
• Australian Stringhalt--epidemiological, clinical and neurological investigations.

  1989cited by this paper
• STRINGHALT IN HORSES: A DISTAL AXONOPATHY

  1986cited by this paper
• An unusual incidence of neurological disease affecting horses during a drought.

  1985cited by this paper
• Reduced myo-inositol levels in cerebrospinal fluid from patients with affective disorder.

  1978cited by this paper
• The identification of myo-inosose-2 and scyllo-inositol in mammalian tissues.

  1968cited by this paper
• The measurement of myo-inositol, myo-inosose-2 and scyllo-inositol in mammalian tissues.

  1968cited by this paper
• [Urinary elimination of mesoinositol in relation to the alimentary system].

  1957cited by this paper
• Preparation of lipide extracts from brain tissue.

  1951cited by this paper
• [Presence of scyllitol and other polyhydric cyclic alcohols in the urine].

  1951cited by this paper

• Movement Disorders and Cerebellar Abiotrophy.

  2022cites this paper
• Shivering and Stringhalt in horses.

  2022cites this paper
• Metabolomics using Fourier transform mass spectrometry

  2019cites this paper
• AssociAtion From the President : Changing the industry ’ s medication culture

  2019cites this paper
• Pasture‐associated stringhalt: Contemporary appraisal of an enigmatic syndrome

  2019cites this paper
• Current neurological investigations : Advantages and limits of routinely used approaches and techniques

  2017influential citation
• : contemporary appraisal of an enigmatic syndrome

  2017cites this paper
• On Combining Wavelets Expansion and Sparse Linear Models for Regression on Metabolomic Data and Biomarker Selection

  2016influential citation
• Dolphin 1D: Improving Automation of Targeted Metabolomics in Multi-matrix Datasets of ^1 1 H-NMR Spectra

  2015cites this paper
• Stringhalt , Shivers , and Other Hard-to-Classify Movement Disorders

  2015cites this paper
• Application de la métabolomique à l’étude du lien entre les expositions environnementales aux pesticides pendant la grossesse et le développement de l’enfant : approches épidémiologique et toxicologique

  2014cites this paper
• ON RECENT ADVANCES IN SUPERVISED RANKING FOR METABOLITE PROFILING

  2014cites this paper
• Mining the brain metabolome to understand behavioural disruptions induced in mouse fed Hypochoeris radicata (L.), a neurotoxic plant for horse.

  2013cites this paper
• Liquid Chromatography Coupled to Mass Spectrometry-Based Metabolomics and the Concept of Biomarker

  2013cites this paper
• Cytotoxic activity of extracts from Hypochaeris radicata.

  2013cites this paper
• Assessment of the health impact of GM plant diets in long-term and multigenerational animal feeding trials: a literature review.

  2012cites this paper
• The nutritive value of grasspea (Lathyrus sativus) and allied species, their toxicity to animals and the role of malnutrition in neurolathyrism.

  2011cites this paper
• Power of a Metabonomic Approach to Investigate an Unknown Nervous Disease

  2011influential citation
• Longitudinal study of Australian stringhalt cases in France.

  2010cites this paper
• Hahnentritt beim Pferd

  2009cites this paper
• Métabolomique, métabonomique et les préoccupations en matière de sécurité alimentaire et de protection de la santé des consommateurs

  2008cites this paper